Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Diabetes_collapsed.gct |
| Phenotype | NGT |
| GeneSet | C2.symbols.gmt#SA_CASPASE_CASCADE |
| Enrichment Score (ES) | 0.40606114 |
| Normalized Enrichment Score (NES) | 1.2398442 |
| Nominal p-value | 0.19026549 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BIRC3 | BIRC3 StanfordSource, GeneCards | baculoviral IAP repeat-containing 3 | 1130 | 0.261 | 0.0706 | Yes |
| 2 | SREBF1 | SREBF1 StanfordSource, GeneCards | sterol regulatory element binding transcription factor 1 | 1404 | 0.241 | 0.1867 | Yes |
| 3 | SCAP | SCAP StanfordSource, GeneCards | SREBP CLEAVAGE-ACTIVATING PROTEIN | 1984 | 0.204 | 0.2621 | Yes |
| 4 | DFFA | DFFA StanfordSource, GeneCards | DNA fragmentation factor, 45kDa, alpha polypeptide | 3327 | 0.144 | 0.2529 | Yes |
| 5 | CASP9 | CASP9 StanfordSource, GeneCards | caspase 9, apoptosis-related cysteine protease | 3920 | 0.121 | 0.2808 | Yes |
| 6 | CASP3 | CASP3 StanfordSource, GeneCards | caspase 3, apoptosis-related cysteine protease | 4260 | 0.109 | 0.3189 | Yes |
| 7 | BIRC2 | BIRC2 StanfordSource, GeneCards | baculoviral IAP repeat-containing 2 | 4313 | 0.107 | 0.3751 | Yes |
| 8 | TNFSF6 | TNFSF6 StanfordSource, GeneCards | tumor necrosis factor (ligand) superfamily, member 6 | 4776 | 0.093 | 0.3960 | Yes |
| 9 | BIRC4 | BIRC4 StanfordSource, GeneCards | baculoviral IAP repeat-containing 4 | 5274 | 0.077 | 0.4061 | Yes |
| 10 | PRF1 | PRF1 StanfordSource, GeneCards | perforin 1 (pore forming protein) | 6765 | 0.034 | 0.3262 | No |
| 11 | APAF1 | APAF1 StanfordSource, GeneCards | apoptotic protease activating factor | 7671 | 0.009 | 0.2711 | No |
| 12 | DFFB | DFFB StanfordSource, GeneCards | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 7715 | 0.008 | 0.2725 | No |
| 13 | GZMB | GZMB StanfordSource, GeneCards | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 8141 | -0.005 | 0.2469 | No |
| 14 | CASP8 | CASP8 StanfordSource, GeneCards | caspase 8, apoptosis-related cysteine protease | 8427 | -0.013 | 0.2350 | No |
| 15 | CASP7 | CASP7 StanfordSource, GeneCards | caspase 7, apoptosis-related cysteine protease | 9626 | -0.049 | 0.1824 | No |
| 16 | TNFRSF6 | TNFRSF6 StanfordSource, GeneCards | tumor necrosis factor receptor superfamily, member 6 | 9754 | -0.052 | 0.2030 | No |
| 17 | SREBF2 | SREBF2 StanfordSource, GeneCards | sterol regulatory element binding transcription factor 2 | 11119 | -0.099 | 0.1677 | No |
| 18 | CASP10 | CASP10 StanfordSource, GeneCards | caspase 10, apoptosis-related cysteine protease | 12737 | -0.169 | 0.1541 | No |
