Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Diabetes_collapsed.gct |
| Phenotype | DMT |
| GeneSet | C2.symbols.gmt#mcalpainPathway |
| Enrichment Score (ES) | -0.44719297 |
| Normalized Enrichment Score (NES) | -1.4121084 |
| Nominal p-value | 0.09418838 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.988 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HRAS | HRAS StanfordSource, GeneCards | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 2096 | 0.198 | -0.0749 | No |
| 2 | PRKAR2B | PRKAR2B StanfordSource, GeneCards | protein kinase, cAMP-dependent, regulatory, type II, beta | 3875 | 0.122 | -0.1533 | No |
| 3 | CAPN2 | CAPN2 StanfordSource, GeneCards | calpain 2, (m/II) large subunit | 3955 | 0.120 | -0.1194 | No |
| 4 | PRKAR2A | PRKAR2A StanfordSource, GeneCards | protein kinase, cAMP-dependent, regulatory, type II, alpha | 5264 | 0.078 | -0.1811 | No |
| 5 | PXN | PXN StanfordSource, GeneCards | paxillin | 5875 | 0.060 | -0.2020 | No |
| 6 | PRKACG | PRKACG StanfordSource, GeneCards | protein kinase, cAMP-dependent, catalytic, gamma | 6040 | 0.054 | -0.1952 | No |
| 7 | EGFR | EGFR StanfordSource, GeneCards | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 6563 | 0.040 | -0.2169 | No |
| 8 | MYLK | MYLK StanfordSource, GeneCards | myosin, light polypeptide kinase | 6674 | 0.037 | -0.2123 | No |
| 9 | PRKACB | PRKACB StanfordSource, GeneCards | protein kinase, cAMP-dependent, catalytic, beta | 6699 | 0.036 | -0.2021 | No |
| 10 | TLN1 | TLN1 StanfordSource, GeneCards | talin 1 | 6940 | 0.029 | -0.2084 | No |
| 11 | EGF | EGF StanfordSource, GeneCards | epidermal growth factor (beta-urogastrone) | 7258 | 0.020 | -0.2228 | No |
| 12 | PTK2 | PTK2 StanfordSource, GeneCards | PTK2 protein tyrosine kinase 2 | 9236 | -0.037 | -0.3422 | No |
| 13 | CXCR3 | CXCR3 StanfordSource, GeneCards | chemokine (C-X-C motif) receptor 3 | 10539 | -0.080 | -0.4029 | No |
| 14 | PRKAR1B | PRKAR1B StanfordSource, GeneCards | protein kinase, cAMP-dependent, regulatory, type I, beta | 11080 | -0.098 | -0.4067 | No |
| 15 | VIL2 | VIL2 StanfordSource, GeneCards | villin 2 (ezrin) | 11689 | -0.120 | -0.4079 | Yes |
| 16 | ACTA1 | ACTA1 StanfordSource, GeneCards | actin, alpha 1, skeletal muscle | 12042 | -0.134 | -0.3874 | Yes |
| 17 | MYL2 | MYL2 StanfordSource, GeneCards | myosin, light polypeptide 2, regulatory, cardiac, slow | 12243 | -0.145 | -0.3535 | Yes |
| 18 | ITGB1 | ITGB1 StanfordSource, GeneCards | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 12853 | -0.175 | -0.3369 | Yes |
| 19 | CAPN1 | CAPN1 StanfordSource, GeneCards | calpain 1, (mu/I) large subunit | 13166 | -0.194 | -0.2942 | Yes |
| 20 | MAPK1 | MAPK1 StanfordSource, GeneCards | mitogen-activated protein kinase 1 | 13258 | -0.200 | -0.2350 | Yes |
| 21 | MAPK3 | MAPK3 StanfordSource, GeneCards | mitogen-activated protein kinase 3 | 13499 | -0.216 | -0.1805 | Yes |
| 22 | PRKAR1A | PRKAR1A StanfordSource, GeneCards | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 14947 | -0.432 | -0.1355 | Yes |
| 23 | CAPNS1 | CAPNS1 StanfordSource, GeneCards | calpain, small subunit 1 | 14955 | -0.437 | 0.0067 | Yes |
