Details for gene set chr21[GSEA]

Table: GSEA Results Summary

Dataset	Gender_collapsed.gct
Phenotype	MALE
GeneSet	C1.symbols.gmt#chr21
Enrichment Score (ES)	0.29621306
Normalized Enrichment Score (NES)	1.1967243
Nominal p-value	0.21052632
FDR q-value	1.0
FWER p-Value	0.947

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RES	CORE_ENRICHMENT
1	TMPRSS3	TMPRSS3 StanfordSource, GeneCards	transmembrane protease, serine 3	150	0.430	0.0128	Yes
2	TIAM1	TIAM1 StanfordSource, GeneCards	T-cell lymphoma invasion and metastasis 1	200	0.409	0.0313	Yes
3	C21orf62	C21orf62 StanfordSource, GeneCards	chromosome 21 open reading frame 62	393	0.357	0.0374	Yes
4	COL6A1	COL6A1 StanfordSource, GeneCards	collagen, type VI, alpha 1	420	0.352	0.0544	Yes
5	C21orf55	C21orf55 StanfordSource, GeneCards	chromosome 21 open reading frame 55	567	0.326	0.0620	Yes
6	BAGE	BAGE StanfordSource, GeneCards	B melanoma antigen	580	0.323	0.0783	Yes
7	C21orf25	C21orf25 StanfordSource, GeneCards	chromosome 21 open reading frame 25	599	0.319	0.0941	Yes
8	S100B	S100B StanfordSource, GeneCards	S100 calcium binding protein, beta (neural)	745	0.301	0.1004	Yes
9	IFP38	IFP38 StanfordSource, GeneCards	IFP38	908	0.283	0.1046	Yes
10	TPTE	TPTE StanfordSource, GeneCards	transmembrane phosphatase with tensin homology	940	0.279	0.1174	Yes
11	BACH1	BACH1 StanfordSource, GeneCards	BTB and CNC homology 1, basic leucine zipper transcription factor 1	1017	0.273	0.1268	Yes
12	AIRE	AIRE StanfordSource, GeneCards	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	1030	0.271	0.1404	Yes
13	HLCS	HLCS StanfordSource, GeneCards	holocarboxylase synthetase (biotin-[proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)	1056	0.269	0.1531	Yes
14	ITSN1	ITSN1 StanfordSource, GeneCards	intersectin 1 (SH3 domain protein)	1073	0.268	0.1662	Yes
15	RUNX1	RUNX1 StanfordSource, GeneCards	runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)	1163	0.258	0.1740	Yes
16	C21orf107	C21orf107 StanfordSource, GeneCards	chromosome 21 open reading frame 107	1170	0.257	0.1873	Yes
17	C21orf7	C21orf7 StanfordSource, GeneCards	chromosome 21 open reading frame 7	1253	0.250	0.1951	Yes
18	CRYZL1	CRYZL1 StanfordSource, GeneCards	crystallin, zeta (quinone reductase)-like 1	1592	0.227	0.1846	Yes
19	C21orf18	C21orf18 StanfordSource, GeneCards	chromosome 21 open reading frame 18	1740	0.219	0.1863	Yes
20	C21orf2	C21orf2 StanfordSource, GeneCards	chromosome 21 open reading frame 2	1778	0.217	0.1954	Yes
21	KCNJ15	KCNJ15 StanfordSource, GeneCards	potassium inwardly-rectifying channel, subfamily J, member 15	1826	0.214	0.2036	Yes
22	CLDN8	CLDN8 StanfordSource, GeneCards	claudin 8	1833	0.213	0.2146	Yes
23	ADARB1	ADARB1 StanfordSource, GeneCards	adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)	1857	0.212	0.2243	Yes
24	C21orf5	C21orf5 StanfordSource, GeneCards	chromosome 21 open reading frame 5	1874	0.211	0.2345	Yes
25	CXADR	CXADR StanfordSource, GeneCards	coxsackie virus and adenovirus receptor	1927	0.208	0.2421	Yes
26	DSCR5	DSCR5 StanfordSource, GeneCards	Down syndrome critical region gene 5	1949	0.207	0.2516	Yes
27	WRB	WRB StanfordSource, GeneCards	tryptophan rich basic protein	2084	0.199	0.2533	Yes
28	C21orf6	C21orf6 StanfordSource, GeneCards	chromosome 21 open reading frame 6	2297	0.190	0.2492	Yes
29	TFF1	TFF1 StanfordSource, GeneCards	trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in)	2494	0.180	0.2456	Yes
30	C21orf45	C21orf45 StanfordSource, GeneCards	chromosome 21 open reading frame 45	2628	0.175	0.2460	Yes
31	KCNJ6	KCNJ6 StanfordSource, GeneCards	potassium inwardly-rectifying channel, subfamily J, member 6	2657	0.173	0.2533	Yes
32	CLDN14	CLDN14 StanfordSource, GeneCards	claudin 14	2697	0.171	0.2598	Yes
33	DONSON	DONSON StanfordSource, GeneCards	downstream neighbor of SON	2777	0.168	0.2634	Yes
34	ADAMTS5	ADAMTS5 StanfordSource, GeneCards	a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)	2975	0.159	0.2587	Yes
35	CHAF1B	CHAF1B StanfordSource, GeneCards	chromatin assembly factor 1, subunit B (p60)	2981	0.159	0.2669	Yes
36	MRPS6	MRPS6 StanfordSource, GeneCards	mitochondrial ribosomal protein S6	3092	0.154	0.2677	Yes
37	SAMSN1	SAMSN1 StanfordSource, GeneCards	SAM domain, SH3 domain and nuclear localisation signals, 1	3104	0.154	0.2751	Yes
38	WDR4	WDR4 StanfordSource, GeneCards	WD repeat domain 4	3298	0.145	0.2700	Yes
39	C21orf33	C21orf33 StanfordSource, GeneCards	chromosome 21 open reading frame 33	3325	0.145	0.2759	Yes
40	B3GALT5	B3GALT5 StanfordSource, GeneCards	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5	3372	0.143	0.2804	Yes
41	IFNAR2	IFNAR2 StanfordSource, GeneCards	interferon (alpha, beta and omega) receptor 2	3398	0.141	0.2863	Yes
42	D21S2056E	D21S2056E StanfordSource, GeneCards	DNA segment on chromosome 21 (unique) 2056 expressed sequence	3545	0.136	0.2837	Yes
43	TTC3	TTC3 StanfordSource, GeneCards	tetratricopeptide repeat domain 3	3582	0.134	0.2884	Yes
44	COL18A1	COL18A1 StanfordSource, GeneCards	collagen, type XVIII, alpha 1	3814	0.125	0.2796	Yes
45	C21orf108	C21orf108 StanfordSource, GeneCards	chromosome 21 open reading frame 108	3835	0.124	0.2849	Yes
46	COL6A2	COL6A2 StanfordSource, GeneCards	collagen, type VI, alpha 2	3879	0.123	0.2886	Yes
47	GRIK1	GRIK1 StanfordSource, GeneCards	glutamate receptor, ionotropic, kainate 1	3901	0.122	0.2936	Yes
48	SH3BGR	SH3BGR StanfordSource, GeneCards	SH3 domain binding glutamic acid-rich protein	3958	0.119	0.2962	Yes
49	DSCAM	DSCAM StanfordSource, GeneCards	Down syndrome cell adhesion molecule	4224	0.110	0.2843	No
50	CSTB	CSTB StanfordSource, GeneCards	cystatin B (stefin B)	4279	0.108	0.2865	No
51	SYNJ1	SYNJ1 StanfordSource, GeneCards	synaptojanin 1	4538	0.100	0.2745	No
52	CRYAA	CRYAA StanfordSource, GeneCards	crystallin, alpha A	4619	0.098	0.2743	No
53	MCM3APAS	MCM3APAS StanfordSource, GeneCards	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein, antisense	4931	0.088	0.2582	No
54	KCNE1	KCNE1 StanfordSource, GeneCards	potassium voltage-gated channel, Isk-related family, member 1	4963	0.087	0.2607	No
55	LSS	LSS StanfordSource, GeneCards	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	5179	0.080	0.2506	No
56	PRSS7	PRSS7 StanfordSource, GeneCards	protease, serine, 7 (enterokinase)	5227	0.079	0.2516	No
57	ZCWCC3	ZCWCC3 StanfordSource, GeneCards	zinc finger, CW-type with coiled-coil domain 3	5276	0.077	0.2525	No
58	KCNE2	KCNE2 StanfordSource, GeneCards	potassium voltage-gated channel, Isk-related family, member 2	5473	0.070	0.2431	No
59	ETS2	ETS2 StanfordSource, GeneCards	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	5524	0.068	0.2434	No
60	DSCR6	DSCR6 StanfordSource, GeneCards	Down syndrome critical region gene 6	5904	0.058	0.2210	No
61	DYRK1A	DYRK1A StanfordSource, GeneCards	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	6054	0.054	0.2139	No
62	HRMT1L1	HRMT1L1 StanfordSource, GeneCards	HMT1 hnRNP methyltransferase-like 1 (S. cerevisiae)	6065	0.053	0.2161	No
63	USP16	USP16 StanfordSource, GeneCards	ubiquitin specific protease 16	6075	0.053	0.2183	No
64	IFNGR2	IFNGR2 StanfordSource, GeneCards	interferon gamma receptor 2 (interferon gamma transducer 1)	6347	0.045	0.2026	No
65	AGPAT3	AGPAT3 StanfordSource, GeneCards	1-acylglycerol-3-phosphate O-acyltransferase 3	6478	0.041	0.1961	No
66	CHODL	CHODL StanfordSource, GeneCards	chondrolectin	6610	0.037	0.1893	No
67	TMPRSS2	TMPRSS2 StanfordSource, GeneCards	transmembrane protease, serine 2	6612	0.037	0.1912	No
68	C21orf59	C21orf59 StanfordSource, GeneCards	chromosome 21 open reading frame 59	6871	0.030	0.1755	No
69	HUNK	HUNK StanfordSource, GeneCards	hormonally upregulated Neu-associated kinase	6889	0.029	0.1759	No
70	NCAM2	NCAM2 StanfordSource, GeneCards	neural cell adhesion molecule 2	6955	0.028	0.1730	No
71	BTG3	BTG3 StanfordSource, GeneCards	BTG family, member 3	7144	0.022	0.1616	No
72	PCP4	PCP4 StanfordSource, GeneCards	Purkinje cell protein 4	7185	0.021	0.1600	No
73	CBR1	CBR1 StanfordSource, GeneCards	carbonyl reductase 1	7263	0.018	0.1558	No
74	HSF2BP	HSF2BP StanfordSource, GeneCards	heat shock transcription factor 2 binding protein	7293	0.017	0.1548	No
75	PCNT2	PCNT2 StanfordSource, GeneCards	pericentrin 2 (kendrin)	7340	0.016	0.1526	No
76	CLDN11	CLDN11 StanfordSource, GeneCards	claudin 11 (oligodendrocyte transmembrane protein)	7466	0.012	0.1448	No
77	PFKL	PFKL StanfordSource, GeneCards	phosphofructokinase, liver	7613	0.008	0.1354	No
78	TFF2	TFF2 StanfordSource, GeneCards	trefoil factor 2 (spasmolytic protein 1)	7635	0.007	0.1344	No
79	SOD1	SOD1 StanfordSource, GeneCards	superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))	7677	0.006	0.1320	No
80	ABCG1	ABCG1 StanfordSource, GeneCards	ATP-binding cassette, sub-family G (WHITE), member 1	7818	0.001	0.1226	No
81	PWP2H	PWP2H StanfordSource, GeneCards	PWP2 periodic tryptophan protein homolog (yeast)	8027	-0.005	0.1089	No
82	OLIG2	OLIG2 StanfordSource, GeneCards	oligodendrocyte lineage transcription factor 2	8029	-0.005	0.1091	No
83	DSCR3	DSCR3 StanfordSource, GeneCards	Down syndrome critical region gene 3	8045	-0.005	0.1084	No
84	SLC19A1	SLC19A1 StanfordSource, GeneCards	solute carrier family 19 (folate transporter), member 1	8402	-0.015	0.0853	No
85	MCM3AP	MCM3AP StanfordSource, GeneCards	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein	8406	-0.015	0.0859	No
86	ITGB2	ITGB2 StanfordSource, GeneCards	integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)	8505	-0.018	0.0803	No
87	ZNF294	ZNF294 StanfordSource, GeneCards	zinc finger protein 294	8601	-0.020	0.0750	No
88	TCF8	TCF8 StanfordSource, GeneCards	transcription factor 8 (represses interleukin 2 expression)	8802	-0.025	0.0629	No
89	DSCR1	DSCR1 StanfordSource, GeneCards	Down syndrome critical region gene 1	8957	-0.030	0.0542	No
90	C21orf66	C21orf66 StanfordSource, GeneCards	chromosome 21 open reading frame 66	9011	-0.031	0.0523	No
91	PDE9A	PDE9A StanfordSource, GeneCards	phosphodiesterase 9A	9256	-0.038	0.0380	No
92	JAM2	JAM2 StanfordSource, GeneCards	junctional adhesion molecule 2	9261	-0.038	0.0397	No
93	IFNAR1	IFNAR1 StanfordSource, GeneCards	interferon (alpha, beta and omega) receptor 1	9446	-0.044	0.0298	No
94	PDXK	PDXK StanfordSource, GeneCards	pyridoxal (pyridoxine, vitamin B6) kinase	9527	-0.047	0.0269	No
95	PTTG1IP	PTTG1IP StanfordSource, GeneCards	pituitary tumor-transforming 1 interacting protein	9596	-0.049	0.0249	No
96	PPIA	PPIA StanfordSource, GeneCards	peptidylprolyl isomerase A (cyclophilin A)	9872	-0.057	0.0095	No
97	BACE2	BACE2 StanfordSource, GeneCards	beta-site APP-cleaving enzyme 2	9902	-0.058	0.0107	No
98	APP	APP StanfordSource, GeneCards	amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease)	9960	-0.060	0.0100	No
99	TMEM1	TMEM1 StanfordSource, GeneCards	transmembrane protein 1	9966	-0.060	0.0128	No
100	DNMT3L	DNMT3L StanfordSource, GeneCards	DNA (cytosine-5-)-methyltransferase 3-like	10026	-0.062	0.0122	No
101	STCH	STCH StanfordSource, GeneCards	stress 70 protein chaperone, microsome-associated, 60kDa	10225	-0.067	0.0025	No
102	HMGN1	HMGN1 StanfordSource, GeneCards	high-mobility group nucleosome binding domain 1	10491	-0.076	-0.0112	No
103	KIAA0179	KIAA0179 StanfordSource, GeneCards	KIAA0179	10681	-0.083	-0.0195	No
104	C21orf91	C21orf91 StanfordSource, GeneCards	chromosome 21 open reading frame 91	11136	-0.098	-0.0447	No
105	H2BFS	H2BFS StanfordSource, GeneCards	H2B histone family, member S	11390	-0.107	-0.0559	No
106	MX1	MX1 StanfordSource, GeneCards	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	11665	-0.117	-0.0681	No
107	USP25	USP25 StanfordSource, GeneCards	ubiquitin specific protease 25	11844	-0.123	-0.0735	No
108	NRIP1	NRIP1 StanfordSource, GeneCards	nuclear receptor interacting protein 1	11858	-0.123	-0.0678	No
109	U2AF1	U2AF1 StanfordSource, GeneCards	U2(RNU2) small nuclear RNA auxiliary factor 1	11954	-0.128	-0.0673	No
110	LRRC3	LRRC3 StanfordSource, GeneCards	leucine rich repeat containing 3	12031	-0.131	-0.0655	No
111	SON	SON StanfordSource, GeneCards	SON DNA binding protein	12149	-0.135	-0.0661	No
112	ATP5O	ATP5O StanfordSource, GeneCards	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)	12394	-0.145	-0.0748	No
113	SLC37A1	SLC37A1 StanfordSource, GeneCards	solute carrier family 37 (glycerol-3-phosphate transporter), member 1	12404	-0.146	-0.0676	No
114	ATP5J	ATP5J StanfordSource, GeneCards	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6	12597	-0.154	-0.0723	No
115	PCBP3	PCBP3 StanfordSource, GeneCards	poly(rC) binding protein 3	12888	-0.167	-0.0828	No
116	MRPL39	MRPL39 StanfordSource, GeneCards	mitochondrial ribosomal protein L39	13078	-0.176	-0.0861	No
117	GABPA	GABPA StanfordSource, GeneCards	GA binding protein transcription factor, alpha subunit 60kDa	13225	-0.184	-0.0861	No
118	TFF3	TFF3 StanfordSource, GeneCards	trefoil factor 3 (intestinal)	13271	-0.186	-0.0792	No
119	GART	GART StanfordSource, GeneCards	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	13282	-0.187	-0.0699	No
120	C21orf4	C21orf4 StanfordSource, GeneCards	chromosome 21 open reading frame 4	13525	-0.202	-0.0754	No
121	PKNOX1	PKNOX1 StanfordSource, GeneCards	PBX/knotted 1 homeobox 1	13556	-0.204	-0.0665	No
122	UBASH3A	UBASH3A StanfordSource, GeneCards	ubiquitin associated and SH3 domain containing, A	13580	-0.206	-0.0571	No
123	CBR3	CBR3 StanfordSource, GeneCards	carbonyl reductase 3	13711	-0.214	-0.0545	No
124	FTCD	FTCD StanfordSource, GeneCards	formiminotransferase cyclodeaminase	13978	-0.235	-0.0598	No
125	UBE2G2	UBE2G2 StanfordSource, GeneCards	ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)	14118	-0.245	-0.0561	No
126	DSCR4	DSCR4 StanfordSource, GeneCards	Down syndrome critical region gene 4	14141	-0.247	-0.0444	No
127	CLDN17	CLDN17 StanfordSource, GeneCards	claudin 17	14294	-0.262	-0.0406	No
128	ADAMTS1	ADAMTS1 StanfordSource, GeneCards	a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1	14362	-0.270	-0.0307	No
129	SIM2	SIM2 StanfordSource, GeneCards	single-minded homolog 2 (Drosophila)	14461	-0.283	-0.0223	No
130	DSCR2	DSCR2 StanfordSource, GeneCards	Down syndrome critical region gene 2	14561	-0.297	-0.0131	No
131	CCT8	CCT8 StanfordSource, GeneCards	chaperonin containing TCP1, subunit 8 (theta)	14854	-0.359	-0.0135	No
132	ERG	ERG StanfordSource, GeneCards	v-ets erythroblastosis virus E26 oncogene like (avian)	15034	-0.506	0.0014	No