Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Gender_collapsed.gct |
| Phenotype | MALE |
| GeneSet | C2.symbols.gmt#ANDROGEN_GENES_FROM_NETAFFX |
| Enrichment Score (ES) | 0.3213417 |
| Normalized Enrichment Score (NES) | 1.225019 |
| Nominal p-value | 0.17089678 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.97 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SULT2A1 | SULT2A1 StanfordSource, GeneCards | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1 | 7 | 0.753 | 0.0796 | Yes |
| 2 | TGFB1I1 | TGFB1I1 StanfordSource, GeneCards | transforming growth factor beta 1 induced transcript 1 | 139 | 0.437 | 0.1174 | Yes |
| 3 | AKR1C4 | AKR1C4 StanfordSource, GeneCards | aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) | 208 | 0.406 | 0.1561 | Yes |
| 4 | SCGB2A1 | SCGB2A1 StanfordSource, GeneCards | secretoglobin, family 2A, member 1 | 341 | 0.368 | 0.1864 | Yes |
| 5 | RDH5 | RDH5 StanfordSource, GeneCards | retinol dehydrogenase 5 (11-cis and 9-cis) | 592 | 0.320 | 0.2037 | Yes |
| 6 | ARSE | ARSE StanfordSource, GeneCards | arylsulfatase E (chondrodysplasia punctata 1) | 776 | 0.297 | 0.2231 | Yes |
| 7 | RODH | RODH StanfordSource, GeneCards | 3-hydroxysteroid epimerase | 1020 | 0.273 | 0.2359 | Yes |
| 8 | PPAP2A | PPAP2A StanfordSource, GeneCards | phosphatidic acid phosphatase type 2A | 1040 | 0.270 | 0.2633 | Yes |
| 9 | CYP11B2 | CYP11B2 StanfordSource, GeneCards | cytochrome P450, family 11, subfamily B, polypeptide 2 | 1268 | 0.249 | 0.2747 | Yes |
| 10 | UGT2B4 | UGT2B4 StanfordSource, GeneCards | UDP glycosyltransferase 2 family, polypeptide B4 | 1307 | 0.246 | 0.2984 | Yes |
| 11 | FGF8 | FGF8 StanfordSource, GeneCards | fibroblast growth factor 8 (androgen-induced) | 1469 | 0.235 | 0.3126 | Yes |
| 12 | AKR1D1 | AKR1D1 StanfordSource, GeneCards | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 1896 | 0.210 | 0.3065 | Yes |
| 13 | HSD11B1 | HSD11B1 StanfordSource, GeneCards | hydroxysteroid (11-beta) dehydrogenase 1 | 2142 | 0.197 | 0.3111 | Yes |
| 14 | NCOA4 | NCOA4 StanfordSource, GeneCards | nuclear receptor coactivator 4 | 2292 | 0.190 | 0.3213 | Yes |
| 15 | CYP11B1 | CYP11B1 StanfordSource, GeneCards | cytochrome P450, family 11, subfamily B, polypeptide 1 | 3282 | 0.146 | 0.2709 | No |
| 16 | SRD5A1 | SRD5A1 StanfordSource, GeneCards | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 3913 | 0.121 | 0.2418 | No |
| 17 | HSD17B3 | HSD17B3 StanfordSource, GeneCards | hydroxysteroid (17-beta) dehydrogenase 3 | 4022 | 0.117 | 0.2470 | No |
| 18 | UGT2B15 | UGT2B15 StanfordSource, GeneCards | UDP glycosyltransferase 2 family, polypeptide B15 | 4124 | 0.113 | 0.2523 | No |
| 19 | SHBG | SHBG StanfordSource, GeneCards | sex hormone-binding globulin | 4153 | 0.112 | 0.2624 | No |
| 20 | HSD17B2 | HSD17B2 StanfordSource, GeneCards | hydroxysteroid (17-beta) dehydrogenase 2 | 5038 | 0.085 | 0.2124 | No |
| 21 | TMEPAI | TMEPAI StanfordSource, GeneCards | transmembrane, prostate androgen induced RNA | 5149 | 0.081 | 0.2137 | No |
| 22 | PART1 | PART1 StanfordSource, GeneCards | prostate androgen-regulated transcript 1 | 5291 | 0.076 | 0.2124 | No |
| 23 | HSD17B8 | HSD17B8 StanfordSource, GeneCards | hydroxysteroid (17-beta) dehydrogenase 8 | 5410 | 0.072 | 0.2123 | No |
| 24 | HSD11B2 | HSD11B2 StanfordSource, GeneCards | hydroxysteroid (11-beta) dehydrogenase 2 | 5465 | 0.070 | 0.2161 | No |
| 25 | CRSP6 | CRSP6 StanfordSource, GeneCards | cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa | 5790 | 0.061 | 0.2010 | No |
| 26 | UGT2B28 | UGT2B28 StanfordSource, GeneCards | UDP glycosyltransferase 2 family, polypeptide B28 | 6016 | 0.055 | 0.1918 | No |
| 27 | VDRIP | VDRIP StanfordSource, GeneCards | vitamin D receptor interacting protein | 6099 | 0.052 | 0.1919 | No |
| 28 | GPX5 | GPX5 StanfordSource, GeneCards | glutathione peroxidase 5 (epididymal androgen-related protein) | 6123 | 0.052 | 0.1959 | No |
| 29 | APRIN | APRIN StanfordSource, GeneCards | androgen-induced proliferation inhibitor | 6165 | 0.051 | 0.1985 | No |
| 30 | TNRC11 | TNRC11 StanfordSource, GeneCards | trinucleotide repeat containing 11 (THR-associated protein, 230kDa subunit) | 6258 | 0.048 | 0.1975 | No |
| 31 | HSD3B2 | HSD3B2 StanfordSource, GeneCards | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 | 6289 | 0.047 | 0.2005 | No |
| 32 | TMPRSS2 | TMPRSS2 StanfordSource, GeneCards | transmembrane protease, serine 2 | 6612 | 0.037 | 0.1830 | No |
| 33 | CRISP1 | CRISP1 StanfordSource, GeneCards | cysteine-rich secretory protein 1 | 6885 | 0.029 | 0.1680 | No |
| 34 | KIAA1093 | KIAA1093 StanfordSource, GeneCards | KIAA1093 protein | 6902 | 0.029 | 0.1699 | No |
| 35 | UGT2B17 | UGT2B17 StanfordSource, GeneCards | UDP glycosyltransferase 2 family, polypeptide B17 | 7000 | 0.026 | 0.1663 | No |
| 36 | NSD1 | NSD1 StanfordSource, GeneCards | nuclear receptor binding SET domain protein 1 | 7322 | 0.016 | 0.1466 | No |
| 37 | SULT2B1 | SULT2B1 StanfordSource, GeneCards | sulfotransferase family, cytosolic, 2B, member 1 | 7345 | 0.016 | 0.1468 | No |
| 38 | RODH-4 | RODH-4 StanfordSource, GeneCards | microsomal NAD+-dependent retinol dehydrogenase 4 | 7886 | -0.001 | 0.1109 | No |
| 39 | NR3C1 | NR3C1 StanfordSource, GeneCards | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 8048 | -0.005 | 0.1007 | No |
| 40 | ARSD | ARSD StanfordSource, GeneCards | arylsulfatase D | 8982 | -0.030 | 0.0417 | No |
| 41 | FKBP5 | FKBP5 StanfordSource, GeneCards | FK506 binding protein 5 | 8994 | -0.030 | 0.0442 | No |
| 42 | C20orf14 | C20orf14 StanfordSource, GeneCards | chromosome 20 open reading frame 14 | 9085 | -0.033 | 0.0417 | No |
| 43 | NR1I3 | NR1I3 StanfordSource, GeneCards | nuclear receptor subfamily 1, group I, member 3 | 9619 | -0.049 | 0.0114 | No |
| 44 | RDH11 | RDH11 StanfordSource, GeneCards | retinol dehydrogenase 11 (all-trans and 9-cis) | 9770 | -0.053 | 0.0071 | No |
| 45 | C6orf105 | C6orf105 StanfordSource, GeneCards | chromosome 6 open reading frame 105 | 9893 | -0.058 | 0.0050 | No |
| 46 | FLJ21934 | FLJ21934 StanfordSource, GeneCards | hypothetical protein FLJ21934 | 10481 | -0.076 | -0.0260 | No |
| 47 | NR3C2 | NR3C2 StanfordSource, GeneCards | nuclear receptor subfamily 3, group C, member 2 | 10702 | -0.083 | -0.0318 | No |
| 48 | C18orf1 | C18orf1 StanfordSource, GeneCards | chromosome 18 open reading frame 1 | 10734 | -0.085 | -0.0249 | No |
| 49 | CYP19A1 | CYP19A1 StanfordSource, GeneCards | cytochrome P450, family 19, subfamily A, polypeptide 1 | 10830 | -0.087 | -0.0219 | No |
| 50 | RNF14 | RNF14 StanfordSource, GeneCards | ring finger protein 14 | 11049 | -0.095 | -0.0264 | No |
| 51 | SRD5A2 | SRD5A2 StanfordSource, GeneCards | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 11075 | -0.096 | -0.0179 | No |
| 52 | AR | AR StanfordSource, GeneCards | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 11277 | -0.103 | -0.0203 | No |
| 53 | PPARBP | PPARBP StanfordSource, GeneCards | PPAR binding protein | 11530 | -0.112 | -0.0251 | No |
| 54 | CRSP2 | CRSP2 StanfordSource, GeneCards | cofactor required for Sp1 transcriptional activation, subunit 2, 150kDa | 11821 | -0.122 | -0.0315 | No |
| 55 | FXR2 | FXR2 StanfordSource, GeneCards | fragile X mental retardation, autosomal homolog 2 | 12494 | -0.149 | -0.0604 | No |
| 56 | RWDD1 | RWDD1 StanfordSource, GeneCards | RWD domain containing 1 | 13472 | -0.199 | -0.1044 | No |
| 57 | ABHD2 | ABHD2 StanfordSource, GeneCards | abhydrolase domain containing 2 | 13791 | -0.219 | -0.1023 | No |
| 58 | HSD3B1 | HSD3B1 StanfordSource, GeneCards | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 13988 | -0.236 | -0.0903 | No |
| 59 | AKR1B10 | AKR1B10 StanfordSource, GeneCards | aldo-keto reductase family 1, member B10 (aldose reductase) | 14319 | -0.265 | -0.0841 | No |
| 60 | LCN7 | LCN7 StanfordSource, GeneCards | lipocalin 7 | 14337 | -0.267 | -0.0568 | No |
| 61 | RAN | RAN StanfordSource, GeneCards | RAN, member RAS oncogene family | 15009 | -0.457 | -0.0530 | No |
| 62 | STS | STS StanfordSource, GeneCards | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 15038 | -0.526 | 0.0011 | No |
