Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Gender_collapsed.gct |
| Phenotype | MALE |
| GeneSet | C2.symbols.gmt#EMT_DOWN |
| Enrichment Score (ES) | 0.38768905 |
| Normalized Enrichment Score (NES) | 1.2450788 |
| Nominal p-value | 0.16760564 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.964 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | JUP | JUP StanfordSource, GeneCards | junction plakoglobin | 189 | 0.413 | 0.0591 | Yes |
| 2 | TIAM1 | TIAM1 StanfordSource, GeneCards | T-cell lymphoma invasion and metastasis 1 | 200 | 0.409 | 0.1295 | Yes |
| 3 | ITPR1 | ITPR1 StanfordSource, GeneCards | inositol 1,4,5-triphosphate receptor, type 1 | 264 | 0.386 | 0.1924 | Yes |
| 4 | TACSTD1 | TACSTD1 StanfordSource, GeneCards | tumor-associated calcium signal transducer 1 | 452 | 0.345 | 0.2398 | Yes |
| 5 | IRF6 | IRF6 StanfordSource, GeneCards | interferon regulatory factor 6 | 652 | 0.311 | 0.2806 | Yes |
| 6 | CTGF | CTGF StanfordSource, GeneCards | connective tissue growth factor | 1031 | 0.271 | 0.3025 | Yes |
| 7 | TGFB3 | TGFB3 StanfordSource, GeneCards | transforming growth factor, beta 3 | 1366 | 0.242 | 0.3223 | Yes |
| 8 | KITLG | KITLG StanfordSource, GeneCards | KIT ligand | 1442 | 0.237 | 0.3584 | Yes |
| 9 | CDH1 | CDH1 StanfordSource, GeneCards | cadherin 1, type 1, E-cadherin (epithelial) | 1595 | 0.227 | 0.3877 | Yes |
| 10 | TIMP3 | TIMP3 StanfordSource, GeneCards | tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 2352 | 0.187 | 0.3698 | No |
| 11 | SGK | SGK StanfordSource, GeneCards | serum/glucocorticoid regulated kinase | 3356 | 0.143 | 0.3279 | No |
| 12 | TGM2 | TGM2 StanfordSource, GeneCards | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 4008 | 0.117 | 0.3050 | No |
| 13 | FLNA | FLNA StanfordSource, GeneCards | filamin A, alpha (actin binding protein 280) | 4375 | 0.105 | 0.2989 | No |
| 14 | THBS1 | THBS1 StanfordSource, GeneCards | thrombospondin 1 | 4489 | 0.101 | 0.3089 | No |
| 15 | FOSB | FOSB StanfordSource, GeneCards | FBJ murine osteosarcoma viral oncogene homolog B | 4575 | 0.099 | 0.3205 | No |
| 16 | BCL6 | BCL6 StanfordSource, GeneCards | B-cell CLL/lymphoma 6 (zinc finger protein 51) | 4773 | 0.093 | 0.3235 | No |
| 17 | F3 | F3 StanfordSource, GeneCards | coagulation factor III (thromboplastin, tissue factor) | 4946 | 0.088 | 0.3273 | No |
| 18 | KLF2 | KLF2 StanfordSource, GeneCards | Kruppel-like factor 2 (lung) | 5311 | 0.075 | 0.3161 | No |
| 19 | STAT5A | STAT5A StanfordSource, GeneCards | signal transducer and activator of transcription 5A | 5540 | 0.068 | 0.3127 | No |
| 20 | SERPINB5 | SERPINB5 StanfordSource, GeneCards | serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 | 7292 | 0.017 | 0.1991 | No |
| 21 | ITGB5 | ITGB5 StanfordSource, GeneCards | integrin, beta 5 | 7405 | 0.013 | 0.1940 | No |
| 22 | CTSH | CTSH StanfordSource, GeneCards | cathepsin H | 7430 | 0.013 | 0.1946 | No |
| 23 | NUMB | NUMB StanfordSource, GeneCards | numb homolog (Drosophila) | 7476 | 0.012 | 0.1936 | No |
| 24 | EGR2 | EGR2 StanfordSource, GeneCards | early growth response 2 (Krox-20 homolog, Drosophila) | 7832 | 0.000 | 0.1700 | No |
| 25 | FBP2 | FBP2 StanfordSource, GeneCards | fructose-1,6-bisphosphatase 2 | 8124 | -0.007 | 0.1519 | No |
| 26 | NNT | NNT StanfordSource, GeneCards | nicotinamide nucleotide transhydrogenase | 8537 | -0.018 | 0.1276 | No |
| 27 | PKP1 | PKP1 StanfordSource, GeneCards | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 8901 | -0.028 | 0.1083 | No |
| 28 | HMMR | HMMR StanfordSource, GeneCards | hyaluronan-mediated motility receptor (RHAMM) | 9050 | -0.032 | 0.1040 | No |
| 29 | MYH9 | MYH9 StanfordSource, GeneCards | myosin, heavy polypeptide 9, non-muscle | 9252 | -0.038 | 0.0973 | No |
| 30 | ARHGEF1 | ARHGEF1 StanfordSource, GeneCards | Rho guanine nucleotide exchange factor (GEF) 1 | 9869 | -0.057 | 0.0661 | No |
| 31 | DUSP1 | DUSP1 StanfordSource, GeneCards | dual specificity phosphatase 1 | 10917 | -0.090 | 0.0121 | No |
| 32 | PADI2 | PADI2 StanfordSource, GeneCards | peptidyl arginine deiminase, type II | 12067 | -0.132 | -0.0414 | No |
| 33 | ACTN4 | ACTN4 StanfordSource, GeneCards | actinin, alpha 4 | 12118 | -0.134 | -0.0216 | No |
| 34 | GRB7 | GRB7 StanfordSource, GeneCards | growth factor receptor-bound protein 7 | 12613 | -0.155 | -0.0276 | No |
| 35 | RARA | RARA StanfordSource, GeneCards | retinoic acid receptor, alpha | 12631 | -0.155 | -0.0018 | No |
| 36 | ATP1A1 | ATP1A1 StanfordSource, GeneCards | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 13158 | -0.180 | -0.0055 | No |
| 37 | ATF3 | ATF3 StanfordSource, GeneCards | activating transcription factor 3 | 14077 | -0.242 | -0.0246 | No |
| 38 | AMD1 | AMD1 StanfordSource, GeneCards | adenosylmethionine decarboxylase 1 | 14164 | -0.249 | 0.0129 | No |
| 39 | EGR1 | EGR1 StanfordSource, GeneCards | early growth response 1 | 14333 | -0.267 | 0.0481 | No |
