DatasetGender_collapsed.gct
PhenotypeFEMALE
GeneSetC2.symbols.gmt#LEU_DOWN
Enrichment Score (ES)-0.53680146
Normalized Enrichment Score (NES)-1.5197564
Nominal p-value0.116
FDR q-value0.8101136
FWER p-Value0.708
Table: GSEA Results Summary

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERESCORE_ENRICHMENT
1HBDHBD
StanfordSource,  GeneCards
hemoglobin, delta2820.383-0.0039No
2GGA2GGA2
StanfordSource,  GeneCards
golgi associated, gamma adaptin ear containing, ARF binding protein 212240.253-0.0572No
3SPINT2SPINT2
StanfordSource,  GeneCards
serine protease inhibitor, Kunitz type, 215460.230-0.0698No
4ALG8ALG8
StanfordSource,  GeneCards
asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase)15910.227-0.0639No
5POLGPOLG
StanfordSource,  GeneCards
polymerase (DNA directed), gamma17250.220-0.0642No
6EBPEBP
StanfordSource,  GeneCards
emopamil binding protein (sterol isomerase)19380.207-0.0703No
7TUBB5TUBB5
StanfordSource,  GeneCards
tubulin, beta, 520850.199-0.0723No
8NPNP
StanfordSource,  GeneCards
nucleoside phosphorylase23610.186-0.0835No
9XPO6XPO6
StanfordSource,  GeneCards
exportin 635020.137-0.1547No
10PFKMPFKM
StanfordSource,  GeneCards
phosphofructokinase, muscle36480.132-0.1593No
11PTPN6PTPN6
StanfordSource,  GeneCards
protein tyrosine phosphatase, non-receptor type 638620.123-0.1688No
12PSME4PSME4
StanfordSource,  GeneCards
proteasome (prosome, macropain) activator subunit 439460.119-0.1697No
13TGFB1TGFB1
StanfordSource,  GeneCards
transforming growth factor, beta 1 (Camurati-Engelmann disease)39630.119-0.1661No
14STK6STK6
StanfordSource,  GeneCards
serine/threonine kinase 641650.112-0.1752No
15DNAJB6DNAJB6
StanfordSource,  GeneCards
DnaJ (Hsp40) homolog, subfamily B, member 648760.090-0.2194No
16NUP98NUP98
StanfordSource,  GeneCards
nucleoporin 98kDa49560.087-0.2213No
17GCDHGCDH
StanfordSource,  GeneCards
glutaryl-Coenzyme A dehydrogenase54050.072-0.2485No
18RASSF2RASSF2
StanfordSource,  GeneCards
Ras association (RalGDS/AF-6) domain family 256070.066-0.2595No
19SQLESQLE
StanfordSource,  GeneCards
squalene epoxidase59060.058-0.2772No
20BYSLBYSL
StanfordSource,  GeneCards
bystin-like59080.058-0.2750No
21TOMM40TOMM40
StanfordSource,  GeneCards
translocase of outer mitochondrial membrane 40 homolog (yeast)59760.056-0.2773No
22SF3B4SF3B4
StanfordSource,  GeneCards
splicing factor 3b, subunit 4, 49kDa60020.055-0.2769No
23DYRK1ADYRK1A
StanfordSource,  GeneCards
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A60540.054-0.2782No
24RBM14RBM14
StanfordSource,  GeneCards
RNA binding motif protein 1461300.052-0.2812No
25EI24EI24
StanfordSource,  GeneCards
etoposide induced 2.4 mRNA63370.046-0.2933No
26FASNFASN
StanfordSource,  GeneCards
fatty acid synthase64420.042-0.2986No
27POLRMTPOLRMT
StanfordSource,  GeneCards
polymerase (RNA) mitochondrial (DNA directed)64720.042-0.2989No
28GLO1GLO1
StanfordSource,  GeneCards
glyoxalase I66640.036-0.3103No
29LIMK2LIMK2
StanfordSource,  GeneCards
LIM domain kinase 270800.024-0.3373No
30UNGUNG
StanfordSource,  GeneCards
uracil-DNA glycosylase71930.021-0.3440No
31OGFROGFR
StanfordSource,  GeneCards
opioid growth factor receptor72540.019-0.3473No
32ILF3ILF3
StanfordSource,  GeneCards
interleukin enhancer binding factor 3, 90kDa72780.018-0.3481No
33GSPT1GSPT1
StanfordSource,  GeneCards
G1 to S phase transition 172880.017-0.3480No
34PSMD11PSMD11
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1174600.012-0.3590No
35NMT1NMT1
StanfordSource,  GeneCards
N-myristoyltransferase 175500.010-0.3646No
36GARPGARP
StanfordSource,  GeneCards
glycoprotein A repetitions predominant76820.005-0.3732No
37SFRS2SFRS2
StanfordSource,  GeneCards
splicing factor, arginine/serine-rich 28158-0.008-0.4048No
38MRPL28MRPL28
StanfordSource,  GeneCards
mitochondrial ribosomal protein L288331-0.013-0.4159No
39BACHBACH
StanfordSource,  GeneCards
brain acyl-CoA hydrolase8453-0.016-0.4233No
40MAP2K3MAP2K3
StanfordSource,  GeneCards
mitogen-activated protein kinase kinase 38461-0.017-0.4232No
41DHCR24DHCR24
StanfordSource,  GeneCards
24-dehydrocholesterol reductase8642-0.021-0.4344No
42PSMB7PSMB7
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, beta type, 78655-0.022-0.4344No
43EIF2B4EIF2B4
StanfordSource,  GeneCards
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa8667-0.022-0.4343No
44EMP3EMP3
StanfordSource,  GeneCards
epithelial membrane protein 38704-0.023-0.4358No
45MLF2MLF2
StanfordSource,  GeneCards
myeloid leukemia factor 28728-0.023-0.4364No
46FDPSFDPS
StanfordSource,  GeneCards
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)8859-0.027-0.4441No
47IDI1IDI1
StanfordSource,  GeneCards
isopentenyl-diphosphate delta isomerase8875-0.027-0.4441No
48ERP70ERP70
StanfordSource,  GeneCards
protein disulfide isomerase related protein (calcium-binding protein, intestinal-related)8892-0.028-0.4441No
49CYC1CYC1
StanfordSource,  GeneCards
cytochrome c-19029-0.032-0.4520No
50CTSCCTSC
StanfordSource,  GeneCards
cathepsin C9099-0.033-0.4553No
51TCEB1TCEB1
StanfordSource,  GeneCards
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)9177-0.036-0.4591No
52TUBA1TUBA1
StanfordSource,  GeneCards
tubulin, alpha 1 (testis specific)9293-0.039-0.4653No
53WDR1WDR1
StanfordSource,  GeneCards
WD repeat domain 19352-0.041-0.4676No
54HPRT1HPRT1
StanfordSource,  GeneCards
hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)9583-0.048-0.4811No
55MMP15MMP15
StanfordSource,  GeneCards
matrix metalloproteinase 15 (membrane-inserted)9826-0.056-0.4952No
56MRPL12MRPL12
StanfordSource,  GeneCards
mitochondrial ribosomal protein L129894-0.058-0.4974No
57MTHFD1MTHFD1
StanfordSource,  GeneCards
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase9956-0.059-0.4992No
58COPB2COPB2
StanfordSource,  GeneCards
coatomer protein complex, subunit beta 2 (beta prime)10049-0.062-0.5030No
59PGK1PGK1
StanfordSource,  GeneCards
phosphoglycerate kinase 110199-0.067-0.5104No
60TK1TK1
StanfordSource,  GeneCards
thymidine kinase 1, soluble10219-0.067-0.5090No
61TCFL4TCFL4
StanfordSource,  GeneCards
transcription factor-like 410286-0.070-0.5107No
62FKBP2FKBP2
StanfordSource,  GeneCards
FK506 binding protein 2, 13kDa10295-0.070-0.5085No
63SCDSCD
StanfordSource,  GeneCards
stearoyl-CoA desaturase (delta-9-desaturase)10356-0.072-0.5097No
64CCT4CCT4
StanfordSource,  GeneCards
chaperonin containing TCP1, subunit 4 (delta)10376-0.073-0.5081No
65EMDEMD
StanfordSource,  GeneCards
emerin (Emery-Dreifuss muscular dystrophy)10381-0.073-0.5056No
66ME2ME2
StanfordSource,  GeneCards
malic enzyme 2, NAD(+)-dependent, mitochondrial10537-0.078-0.5129No
67PTMSPTMS
StanfordSource,  GeneCards
parathymosin10623-0.081-0.5155No
68KIAA0179KIAA0179
StanfordSource,  GeneCards
KIAA017910681-0.083-0.5161No
69NXF1NXF1
StanfordSource,  GeneCards
nuclear RNA export factor 110712-0.084-0.5148No
70AF1QAF1Q
StanfordSource,  GeneCards
ALL1-fused gene from chromosome 1q10902-0.090-0.5240No
71PAPOLAPAPOLA
StanfordSource,  GeneCards
poly(A) polymerase alpha10960-0.092-0.5242No
72CADCAD
StanfordSource,  GeneCards
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase11131-0.098-0.5318No
73BRD2BRD2
StanfordSource,  GeneCards
bromodomain containing 211152-0.099-0.5293No
74EIF4G1EIF4G1
StanfordSource,  GeneCards
eukaryotic translation initiation factor 4 gamma, 111170-0.100-0.5265No
75FKBP4FKBP4
StanfordSource,  GeneCards
FK506 binding protein 4, 59kDa11250-0.103-0.5278No
76HSPC111HSPC111
StanfordSource,  GeneCards
hypothetical protein HSPC11111308-0.105-0.5275No
77CCNB1CCNB1
StanfordSource,  GeneCards
cyclin B111384-0.107-0.5284No
78MRPS12MRPS12
StanfordSource,  GeneCards
mitochondrial ribosomal protein S1211404-0.108-0.5254No
79PGAM1PGAM1
StanfordSource,  GeneCards
phosphoglycerate mutase 1 (brain)11445-0.109-0.5238No
80CCT5CCT5
StanfordSource,  GeneCards
chaperonin containing TCP1, subunit 5 (epsilon)11470-0.110-0.5211No
81TNFRSF1ATNFRSF1A
StanfordSource,  GeneCards
tumor necrosis factor receptor superfamily, member 1A11546-0.113-0.5218No
82SLC29A1SLC29A1
StanfordSource,  GeneCards
solute carrier family 29 (nucleoside transporters), member 111639-0.116-0.5234No
83PSMA7PSMA7
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, alpha type, 711744-0.119-0.5257No
84DHX9DHX9
StanfordSource,  GeneCards
DEAH (Asp-Glu-Ala-His) box polypeptide 911910-0.126-0.5319Yes
85TIMM17ATIMM17A
StanfordSource,  GeneCards
translocase of inner mitochondrial membrane 17 homolog A (yeast)11913-0.126-0.5271Yes
86CHC1CHC1
StanfordSource,  GeneCards
chromosome condensation 111918-0.126-0.5224Yes
87CDC20CDC20
StanfordSource,  GeneCards
CDC20 cell division cycle 20 homolog (S. cerevisiae)11931-0.127-0.5183Yes
88SEC61BSEC61B
StanfordSource,  GeneCards
Sec61 beta subunit12091-0.133-0.5237Yes
89HSPA4HSPA4
StanfordSource,  GeneCards
heat shock 70kDa protein 412125-0.134-0.5207Yes
90DKFZP564F0522DKFZP564F0522
StanfordSource,  GeneCards
DKFZP564F0522 protein12171-0.136-0.5184Yes
91KIAA1055KIAA1055
StanfordSource,  GeneCards
KIAA1055 protein12197-0.137-0.5147Yes
92CCNA2CCNA2
StanfordSource,  GeneCards
cyclin A212219-0.138-0.5107Yes
93DHRS1DHRS1
StanfordSource,  GeneCards
dehydrogenase/reductase (SDR family) member 112318-0.142-0.5118Yes
94PSMF1PSMF1
StanfordSource,  GeneCards
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)12366-0.144-0.5093Yes
95PSMD14PSMD14
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1412552-0.152-0.5158Yes
96DOC-1RDOC-1R
StanfordSource,  GeneCards
tumor suppressor deleted in oral cancer-related 112575-0.153-0.5113Yes
97LDHBLDHB
StanfordSource,  GeneCards
lactate dehydrogenase B12590-0.153-0.5062Yes
98NBL1NBL1
StanfordSource,  GeneCards
neuroblastoma, suppression of tumorigenicity 112625-0.155-0.5024Yes
99SSBSSB
StanfordSource,  GeneCards
Sjogren syndrome antigen B (autoantigen La)12627-0.155-0.4964Yes
100NOL5ANOL5A
StanfordSource,  GeneCards
nucleolar protein 5A (56kDa with KKE/D repeat)12636-0.155-0.4909Yes
101TRIP13TRIP13
StanfordSource,  GeneCards
thyroid hormone receptor interactor 1312687-0.157-0.4881Yes
102UMPSUMPS
StanfordSource,  GeneCards
uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)12701-0.158-0.4828Yes
103TDGTDG
StanfordSource,  GeneCards
thymine-DNA glycosylase12742-0.160-0.4792Yes
104ACAT2ACAT2
StanfordSource,  GeneCards
acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)12756-0.161-0.4738Yes
105KIAA0152KIAA0152
StanfordSource,  GeneCards
KIAA0152 gene product12757-0.161-0.4675Yes
106VRK1VRK1
StanfordSource,  GeneCards
vaccinia related kinase 112779-0.162-0.4626Yes
107FLJ12443FLJ12443
StanfordSource,  GeneCards
hypothetical protein FLJ1244312917-0.168-0.4652Yes
108MGC5508MGC5508
StanfordSource,  GeneCards
hypothetical protein MGC550812998-0.172-0.4638Yes
109AHSA1AHSA1
StanfordSource,  GeneCards
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)13116-0.178-0.4647Yes
110CSE1LCSE1L
StanfordSource,  GeneCards
CSE1 chromosome segregation 1-like (yeast)13181-0.181-0.4619Yes
111NOL1NOL1
StanfordSource,  GeneCards
nucleolar protein 1, 120kDa13204-0.182-0.4563Yes
112TFRCTFRC
StanfordSource,  GeneCards
transferrin receptor (p90, CD71)13213-0.183-0.4497Yes
113GARTGART
StanfordSource,  GeneCards
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase13282-0.187-0.4469Yes
114PTBP1PTBP1
StanfordSource,  GeneCards
polypyrimidine tract binding protein 113295-0.188-0.4404Yes
115KIAA0117KIAA0117
StanfordSource,  GeneCards
KIAA0117 protein13317-0.189-0.4344Yes
116PIK3R3PIK3R3
StanfordSource,  GeneCards
phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)13337-0.190-0.4282Yes
117BST2BST2
StanfordSource,  GeneCards
bone marrow stromal cell antigen 213369-0.192-0.4228Yes
118HSPE1HSPE1
StanfordSource,  GeneCards
heat shock 10kDa protein 1 (chaperonin 10)13384-0.193-0.4161Yes
119EIF4G2EIF4G2
StanfordSource,  GeneCards
eukaryotic translation initiation factor 4 gamma, 213385-0.193-0.4086Yes
120VDAC1VDAC1
StanfordSource,  GeneCards
voltage-dependent anion channel 113447-0.198-0.4049Yes
121HUMGT198AHUMGT198A
StanfordSource,  GeneCards
GT198, complete ORF13482-0.200-0.3994Yes
122HSPCBHSPCB
StanfordSource,  GeneCards
heat shock 90kDa protein 1, beta13488-0.200-0.3919Yes
123SNRPA1SNRPA1
StanfordSource,  GeneCards
small nuclear ribonucleoprotein polypeptide A'13499-0.200-0.3847Yes
124HRMT1L2HRMT1L2
StanfordSource,  GeneCards
HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae)13585-0.206-0.3824Yes
125NUTF2NUTF2
StanfordSource,  GeneCards
nuclear transport factor 213615-0.208-0.3762Yes
126PPIBPPIB
StanfordSource,  GeneCards
peptidylprolyl isomerase B (cyclophilin B)13664-0.211-0.3712Yes
127NME2NME2
StanfordSource,  GeneCards
non-metastatic cells 2, protein (NM23B) expressed in13724-0.214-0.3667Yes
128TRIP15TRIP15
StanfordSource,  GeneCards
thyroid receptor interacting protein 1513774-0.218-0.3615Yes
129MRPL3MRPL3
StanfordSource,  GeneCards
mitochondrial ribosomal protein L313866-0.227-0.3587Yes
130EIF5EIF5
StanfordSource,  GeneCards
eukaryotic translation initiation factor 513902-0.229-0.3521Yes
131HSPCAHSPCA
StanfordSource,  GeneCards
heat shock 90kDa protein 1, alpha13977-0.235-0.3479Yes
132ARMETARMET
StanfordSource,  GeneCards
arginine-rich, mutated in early stage tumors14001-0.237-0.3402Yes
133UBCUBC
StanfordSource,  GeneCards
ubiquitin C14050-0.240-0.3340Yes
134KPNA2KPNA2
StanfordSource,  GeneCards
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)14067-0.241-0.3256Yes
135MCM4MCM4
StanfordSource,  GeneCards
MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)14127-0.246-0.3200Yes
136DDX21DDX21
StanfordSource,  GeneCards
DEAD (Asp-Glu-Ala-Asp) box polypeptide 2114142-0.247-0.3112Yes
137NCLNCL
StanfordSource,  GeneCards
nucleolin14155-0.248-0.3023Yes
138AMD1AMD1
StanfordSource,  GeneCards
adenosylmethionine decarboxylase 114164-0.249-0.2931Yes
139TCP1TCP1
StanfordSource,  GeneCards
t-complex 114190-0.251-0.2849Yes
140DDX1DDX1
StanfordSource,  GeneCards
DEAD (Asp-Glu-Ala-Asp) box polypeptide 114259-0.259-0.2794Yes
141PSMA5PSMA5
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, alpha type, 514278-0.261-0.2704Yes
142LDHALDHA
StanfordSource,  GeneCards
lactate dehydrogenase A14299-0.263-0.2614Yes
143ALDOAALDOA
StanfordSource,  GeneCards
aldolase A, fructose-bisphosphate14321-0.265-0.2525Yes
144TOP1TOP1
StanfordSource,  GeneCards
topoisomerase (DNA) I14346-0.268-0.2436Yes
145PDCD4PDCD4
StanfordSource,  GeneCards
programmed cell death 4 (neoplastic transformation inhibitor)14354-0.269-0.2335Yes
146PSMD2PSMD2
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 214368-0.271-0.2238Yes
147SRMSRM
StanfordSource,  GeneCards
spermidine synthase14372-0.272-0.2134Yes
148HSPA5HSPA5
StanfordSource,  GeneCards
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)14441-0.280-0.2070Yes
149HSPA8HSPA8
StanfordSource,  GeneCards
heat shock 70kDa protein 814487-0.286-0.1988Yes
150TEBPTEBP
StanfordSource,  GeneCards
unactive progesterone receptor, 23 kD14488-0.286-0.1876Yes
151CALRCALR
StanfordSource,  GeneCards
calreticulin14572-0.298-0.1815Yes
152ERHERH
StanfordSource,  GeneCards
enhancer of rudimentary homolog (Drosophila)14626-0.308-0.1730Yes
153ADRM1ADRM1
StanfordSource,  GeneCards
adhesion regulating molecule 114647-0.313-0.1621Yes
154PSMD1PSMD1
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 114698-0.323-0.1528Yes
155DNCL1DNCL1
StanfordSource,  GeneCards
dynein, cytoplasmic, light polypeptide 114700-0.323-0.1403Yes
156DNAJA1DNAJA1
StanfordSource,  GeneCards
DnaJ (Hsp40) homolog, subfamily A, member 114731-0.329-0.1294Yes
157CCT2CCT2
StanfordSource,  GeneCards
chaperonin containing TCP1, subunit 2 (beta)14738-0.331-0.1168Yes
158FNBP3FNBP3
StanfordSource,  GeneCards
formin binding protein 314762-0.337-0.1052Yes
159TRA1TRA1
StanfordSource,  GeneCards
tumor rejection antigen (gp96) 114814-0.347-0.0951Yes
160PSMD3PSMD3
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 314877-0.367-0.0849Yes
161RNF126RNF126
StanfordSource,  GeneCards
ring finger protein 12614886-0.369-0.0710Yes
162XRCC5XRCC5
StanfordSource,  GeneCards
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)14895-0.371-0.0570Yes
163CCT6ACCT6A
StanfordSource,  GeneCards
chaperonin containing TCP1, subunit 6A (zeta 1)14918-0.379-0.0436Yes
164CYCSCYCS
StanfordSource,  GeneCards
cytochrome c, somatic14975-0.416-0.0311Yes
165UBE2NUBE2N
StanfordSource,  GeneCards
ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)15004-0.448-0.0154Yes
166ETF1ETF1
StanfordSource,  GeneCards
eukaryotic translation termination factor 115022-0.4800.0022Yes
Table: GSEA details [plain text format]



Fig 1: GSEA_Results   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List



Fig 2: Gender_collapsed.gct   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: Null Distribution for LEU_DOWN   
Histogram of random enrichment scores (real ES = -0.53680146 )