DatasetGender_collapsed.gct
PhenotypeFEMALE
GeneSetC2.symbols.gmt#Proteasome_Degradation
Enrichment Score (ES)-0.64275146
Normalized Enrichment Score (NES)-1.4459488
Nominal p-value0.1222031
FDR q-value0.85332966
FWER p-Value0.804
Table: GSEA Results Summary

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERESCORE_ENRICHMENT
1UBE2D3UBE2D3
StanfordSource,  GeneCards
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)53750.073-0.3435No
2PSMC5PSMC5
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, ATPase, 556250.065-0.3473No
3PSMA1PSMA1
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, alpha type, 168880.029-0.4256No
4PSMD8PSMD8
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 88003-0.004-0.4990No
5PSMB7PSMB7
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, beta type, 78655-0.022-0.5381No
6UBE1LUBE1L
StanfordSource,  GeneCards
ubiquitin-activating enzyme E1-like8944-0.029-0.5516No
7UBE2D1UBE2D1
StanfordSource,  GeneCards
ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)8980-0.030-0.5481No
8PSMC6PSMC6
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, ATPase, 69812-0.055-0.5927No
9H2AFXH2AFX
StanfordSource,  GeneCards
H2A histone family, member X10308-0.070-0.6119No
10UBE2D2UBE2D2
StanfordSource,  GeneCards
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)10518-0.077-0.6108No
11PSMB6PSMB6
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, beta type, 610726-0.084-0.6082No
12UBA52UBA52
StanfordSource,  GeneCards
ubiquitin A-52 residue ribosomal protein fusion product 110820-0.087-0.5974No
13PSMA6PSMA6
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, alpha type, 611032-0.094-0.5931No
14PSMA7PSMA7
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, alpha type, 711744-0.119-0.6172No
15PSMD4PSMD4
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 412129-0.134-0.6166Yes
16MKI67MKI67
StanfordSource,  GeneCards
antigen identified by monoclonal antibody Ki-6712289-0.141-0.5998Yes
17PSMA4PSMA4
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, alpha type, 412453-0.148-0.5819Yes
18PSMC1PSMC1
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, ATPase, 112655-0.156-0.5648Yes
19PSME2PSME2
StanfordSource,  GeneCards
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)13221-0.184-0.5666Yes
20PSMD5PSMD5
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 513452-0.198-0.5434Yes
21UBCUBC
StanfordSource,  GeneCards
ubiquitin C14050-0.240-0.5364Yes
22PSMC4PSMC4
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, ATPase, 414137-0.247-0.4940Yes
23PSMB9PSMB9
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2)14172-0.250-0.4477Yes
24PSMC2PSMC2
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, ATPase, 214230-0.256-0.4017Yes
25PSMD2PSMD2
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 214368-0.271-0.3580Yes
26RPS27ARPS27A
StanfordSource,  GeneCards
ribosomal protein S27a14610-0.304-0.3148Yes
27PSMD1PSMD1
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 114698-0.323-0.2577Yes
28H2AFZH2AFZ
StanfordSource,  GeneCards
H2A histone family, member Z14734-0.330-0.1957Yes
29UBE1UBE1
StanfordSource,  GeneCards
ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing)14782-0.339-0.1328Yes
30PSMD3PSMD3
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, non-ATPase, 314877-0.367-0.0676Yes
31PSMC3PSMC3
StanfordSource,  GeneCards
proteasome (prosome, macropain) 26S subunit, ATPase, 314966-0.4080.0059Yes
Table: GSEA details [plain text format]



Fig 1: GSEA_Results   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List



Fig 2: Gender_collapsed.gct   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: Null Distribution for Proteasome_Degradation   
Histogram of random enrichment scores (real ES = -0.64275146 )