Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Gender_collapsed.gct |
| Phenotype | FEMALE |
| GeneSet | C2.symbols.gmt#SIG_Regulation_of_the_actin_cytoskeleton_by_Rho_GTPases |
| Enrichment Score (ES) | -0.3639784 |
| Normalized Enrichment Score (NES) | -1.3091232 |
| Nominal p-value | 0.10888889 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.903 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MYH2 | MYH2 StanfordSource, GeneCards | myosin, heavy polypeptide 2, skeletal muscle, adult | 405 | 0.354 | 0.0464 | No |
| 2 | PAK4 | PAK4 StanfordSource, GeneCards | p21(CDKN1A)-activated kinase 4 | 494 | 0.337 | 0.1104 | No |
| 3 | FSCN2 | FSCN2 StanfordSource, GeneCards | fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) | 1065 | 0.268 | 0.1282 | No |
| 4 | CDC42 | CDC42 StanfordSource, GeneCards | cell division cycle 42 (GTP binding protein, 25kDa) | 1498 | 0.233 | 0.1477 | No |
| 5 | PAK6 | PAK6 StanfordSource, GeneCards | p21(CDKN1A)-activated kinase 6 | 2314 | 0.189 | 0.1326 | No |
| 6 | ANGPTL2 | ANGPTL2 StanfordSource, GeneCards | angiopoietin-like 2 | 3300 | 0.145 | 0.0972 | No |
| 7 | WASL | WASL StanfordSource, GeneCards | Wiskott-Aldrich syndrome-like | 3813 | 0.125 | 0.0891 | No |
| 8 | GDI1 | GDI1 StanfordSource, GeneCards | GDP dissociation inhibitor 1 | 3906 | 0.121 | 0.1081 | No |
| 9 | FLNA | FLNA StanfordSource, GeneCards | filamin A, alpha (actin binding protein 280) | 4375 | 0.105 | 0.0988 | No |
| 10 | PAK3 | PAK3 StanfordSource, GeneCards | p21 (CDKN1A)-activated kinase 3 | 5503 | 0.069 | 0.0381 | No |
| 11 | WASF1 | WASF1 StanfordSource, GeneCards | WAS protein family, member 1 | 5858 | 0.059 | 0.0268 | No |
| 12 | VASP | VASP StanfordSource, GeneCards | vasodilator-stimulated phosphoprotein | 6397 | 0.044 | 0.0000 | No |
| 13 | ACTG2 | ACTG2 StanfordSource, GeneCards | actin, gamma 2, smooth muscle, enteric | 6493 | 0.041 | 0.0022 | No |
| 14 | ROCK2 | ROCK2 StanfordSource, GeneCards | Rho-associated, coiled-coil containing protein kinase 2 | 6585 | 0.038 | 0.0040 | No |
| 15 | RHO | RHO StanfordSource, GeneCards | rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant) | 6642 | 0.037 | 0.0079 | No |
| 16 | ROCK1 | ROCK1 StanfordSource, GeneCards | Rho-associated, coiled-coil containing protein kinase 1 | 6698 | 0.035 | 0.0114 | No |
| 17 | LIMK1 | LIMK1 StanfordSource, GeneCards | LIM domain kinase 1 | 6994 | 0.027 | -0.0027 | No |
| 18 | MYLK | MYLK StanfordSource, GeneCards | myosin, light polypeptide kinase | 7607 | 0.008 | -0.0417 | No |
| 19 | PAK7 | PAK7 StanfordSource, GeneCards | p21(CDKN1A)-activated kinase 7 | 8225 | -0.010 | -0.0808 | No |
| 20 | ACTR2 | ACTR2 StanfordSource, GeneCards | ARP2 actin-related protein 2 homolog (yeast) | 8767 | -0.024 | -0.1118 | No |
| 21 | FLNC | FLNC StanfordSource, GeneCards | filamin C, gamma (actin binding protein 280) | 8804 | -0.025 | -0.1090 | No |
| 22 | FSCN1 | FSCN1 StanfordSource, GeneCards | fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) | 8996 | -0.030 | -0.1154 | No |
| 23 | GDI2 | GDI2 StanfordSource, GeneCards | GDP dissociation inhibitor 2 | 9044 | -0.032 | -0.1119 | No |
| 24 | PFN2 | PFN2 StanfordSource, GeneCards | profilin 2 | 9237 | -0.038 | -0.1168 | No |
| 25 | PAK1 | PAK1 StanfordSource, GeneCards | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 9468 | -0.045 | -0.1228 | No |
| 26 | FSCN3 | FSCN3 StanfordSource, GeneCards | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus) | 9505 | -0.046 | -0.1157 | No |
| 27 | PAK2 | PAK2 StanfordSource, GeneCards | p21 (CDKN1A)-activated kinase 2 | 11832 | -0.123 | -0.2451 | No |
| 28 | AKT1 | AKT1 StanfordSource, GeneCards | v-akt murine thymoma viral oncogene homolog 1 | 13061 | -0.175 | -0.2905 | No |
| 29 | ACTG1 | ACTG1 StanfordSource, GeneCards | actin, gamma 1 | 13873 | -0.227 | -0.2974 | No |
| 30 | ACTR3 | ACTR3 StanfordSource, GeneCards | ARP3 actin-related protein 3 homolog (yeast) | 14874 | -0.366 | -0.2881 | Yes |
| 31 | CFL1 | CFL1 StanfordSource, GeneCards | cofilin 1 (non-muscle) | 14884 | -0.368 | -0.2123 | Yes |
| 32 | PFN1 | PFN1 StanfordSource, GeneCards | profilin 1 | 14999 | -0.439 | -0.1289 | Yes |
| 33 | RPS4X | RPS4X StanfordSource, GeneCards | ribosomal protein S4, X-linked | 15048 | -0.639 | 0.0005 | Yes |
