Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Gender_collapsed.gct |
| Phenotype | FEMALE |
| GeneSet | C2.symbols.gmt#mRNA_processing |
| Enrichment Score (ES) | -0.5497124 |
| Normalized Enrichment Score (NES) | -1.4077495 |
| Nominal p-value | 0.16082475 |
| FDR q-value | 0.8413046 |
| FWER p-Value | 0.841 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SFRS5 | SFRS5 StanfordSource, GeneCards | splicing factor, arginine/serine-rich 5 | 3762 | 0.127 | -0.2266 | No |
| 2 | SIP1 | SIP1 StanfordSource, GeneCards | survival of motor neuron protein interacting protein 1 | 4148 | 0.112 | -0.2310 | No |
| 3 | SFRS11 | SFRS11 StanfordSource, GeneCards | splicing factor, arginine/serine-rich 11 | 4249 | 0.109 | -0.2171 | No |
| 4 | SFRS8 | SFRS8 StanfordSource, GeneCards | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 5789 | 0.061 | -0.3081 | No |
| 5 | SF3A3 | SF3A3 StanfordSource, GeneCards | splicing factor 3a, subunit 3, 60kDa | 5803 | 0.060 | -0.2976 | No |
| 6 | SNRP70 | SNRP70 StanfordSource, GeneCards | small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen) | 5924 | 0.057 | -0.2948 | No |
| 7 | SMNDC1 | SMNDC1 StanfordSource, GeneCards | survival motor neuron domain containing 1 | 5945 | 0.057 | -0.2854 | No |
| 8 | SF3B4 | SF3B4 StanfordSource, GeneCards | splicing factor 3b, subunit 4, 49kDa | 6002 | 0.055 | -0.2788 | No |
| 9 | PRPF18 | PRPF18 StanfordSource, GeneCards | PRP18 pre-mRNA processing factor 18 homolog (yeast) | 6182 | 0.050 | -0.2813 | No |
| 10 | PRPF8 | PRPF8 StanfordSource, GeneCards | PRP8 pre-mRNA processing factor 8 homolog (yeast) | 6393 | 0.044 | -0.2870 | No |
| 11 | NONO | NONO StanfordSource, GeneCards | non-POU domain containing, octamer-binding | 7804 | 0.001 | -0.3807 | No |
| 12 | SFRS7 | SFRS7 StanfordSource, GeneCards | splicing factor, arginine/serine-rich 7, 35kDa | 7841 | 0.000 | -0.3831 | No |
| 13 | SFRS2 | SFRS2 StanfordSource, GeneCards | splicing factor, arginine/serine-rich 2 | 8158 | -0.008 | -0.4026 | No |
| 14 | ELAVL4 | ELAVL4 StanfordSource, GeneCards | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) | 8777 | -0.024 | -0.4392 | No |
| 15 | KHDRBS1 | KHDRBS1 StanfordSource, GeneCards | KH domain containing, RNA binding, signal transduction associated 1 | 8876 | -0.027 | -0.4406 | No |
| 16 | CPSF5 | CPSF5 StanfordSource, GeneCards | cleavage and polyadenylation specific factor 5, 25 kDa | 9445 | -0.044 | -0.4701 | No |
| 17 | PRPF3 | PRPF3 StanfordSource, GeneCards | PRP3 pre-mRNA processing factor 3 homolog (yeast) | 9973 | -0.060 | -0.4939 | No |
| 18 | SNRPB2 | SNRPB2 StanfordSource, GeneCards | small nuclear ribonucleoprotein polypeptide B'' | 10812 | -0.087 | -0.5333 | Yes |
| 19 | LSM1 | LSM1 StanfordSource, GeneCards | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 10813 | -0.087 | -0.5169 | Yes |
| 20 | DHX15 | DHX15 StanfordSource, GeneCards | DEAH (Asp-Glu-Ala-His) box polypeptide 15 | 11155 | -0.099 | -0.5209 | Yes |
| 21 | CPSF6 | CPSF6 StanfordSource, GeneCards | cleavage and polyadenylation specific factor 6, 68kDa | 11385 | -0.107 | -0.5160 | Yes |
| 22 | FUSIP1 | FUSIP1 StanfordSource, GeneCards | FUS interacting protein (serine-arginine rich) 1 | 11419 | -0.108 | -0.4978 | Yes |
| 23 | SFRS4 | SFRS4 StanfordSource, GeneCards | splicing factor, arginine/serine-rich 4 | 11441 | -0.109 | -0.4786 | Yes |
| 24 | SF3B3 | SF3B3 StanfordSource, GeneCards | splicing factor 3b, subunit 3, 130kDa | 11529 | -0.112 | -0.4632 | Yes |
| 25 | U2AF1 | U2AF1 StanfordSource, GeneCards | U2(RNU2) small nuclear RNA auxiliary factor 1 | 11954 | -0.128 | -0.4674 | Yes |
| 26 | CUGBP1 | CUGBP1 StanfordSource, GeneCards | CUG triplet repeat, RNA binding protein 1 | 11998 | -0.129 | -0.4459 | Yes |
| 27 | SFRS2IP | SFRS2IP StanfordSource, GeneCards | splicing factor, arginine/serine-rich 2, interacting protein | 12062 | -0.132 | -0.4252 | Yes |
| 28 | HNRPA0 | HNRPA0 StanfordSource, GeneCards | heterogeneous nuclear ribonucleoprotein A0 | 12337 | -0.143 | -0.4165 | Yes |
| 29 | USP39 | USP39 StanfordSource, GeneCards | ubiquitin specific protease 39 | 12426 | -0.146 | -0.3948 | Yes |
| 30 | LSM3 | LSM3 StanfordSource, GeneCards | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 12555 | -0.152 | -0.3746 | Yes |
| 31 | KHSRP | KHSRP StanfordSource, GeneCards | KH-type splicing regulatory protein (FUSE binding protein 2) | 12726 | -0.159 | -0.3559 | Yes |
| 32 | HNRPR | HNRPR StanfordSource, GeneCards | heterogeneous nuclear ribonucleoprotein R | 12748 | -0.160 | -0.3270 | Yes |
| 33 | LSM5 | LSM5 StanfordSource, GeneCards | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 12896 | -0.168 | -0.3052 | Yes |
| 34 | HNRPA1 | HNRPA1 StanfordSource, GeneCards | heterogeneous nuclear ribonucleoprotein A1 | 12970 | -0.171 | -0.2778 | Yes |
| 35 | SLBP | SLBP StanfordSource, GeneCards | stem-loop (histone) binding protein | 13035 | -0.174 | -0.2493 | Yes |
| 36 | SFPQ | SFPQ StanfordSource, GeneCards | splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) | 13200 | -0.182 | -0.2259 | Yes |
| 37 | PTBP1 | PTBP1 StanfordSource, GeneCards | polypyrimidine tract binding protein 1 | 13295 | -0.188 | -0.1967 | Yes |
| 38 | SFRS10 | SFRS10 StanfordSource, GeneCards | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 13463 | -0.198 | -0.1704 | Yes |
| 39 | SFRS1 | SFRS1 StanfordSource, GeneCards | splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) | 13806 | -0.220 | -0.1516 | Yes |
| 40 | SPOP | SPOP StanfordSource, GeneCards | speckle-type POZ protein | 14451 | -0.282 | -0.1413 | Yes |
| 41 | SF3A1 | SF3A1 StanfordSource, GeneCards | splicing factor 3a, subunit 1, 120kDa | 14454 | -0.282 | -0.0882 | Yes |
| 42 | U2AF2 | U2AF2 StanfordSource, GeneCards | U2 (RNU2) small nuclear RNA auxiliary factor 2 | 14663 | -0.317 | -0.0424 | Yes |
| 43 | SFRS9 | SFRS9 StanfordSource, GeneCards | splicing factor, arginine/serine-rich 9 | 14864 | -0.363 | 0.0127 | Yes |
