DatasetGender_collapsed.gct
PhenotypeFEMALE
GeneSetC2.symbols.gmt#mRNA_splicing
Enrichment Score (ES)-0.5970093
Normalized Enrichment Score (NES)-1.6376957
Nominal p-value0.033707865
FDR q-value0.53688675
FWER p-Value0.505
Table: GSEA Results Summary

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERESCORE_ENRICHMENT
1SFRS11SFRS11
StanfordSource,  GeneCards
splicing factor, arginine/serine-rich 1142490.109-0.2666No
2IVNS1ABPIVNS1ABP
StanfordSource,  GeneCards
influenza virus NS1A binding protein44140.104-0.2617No
3SF3A3SF3A3
StanfordSource,  GeneCards
splicing factor 3a, subunit 3, 60kDa58030.060-0.3450No
4SNRP70SNRP70
StanfordSource,  GeneCards
small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)59240.057-0.3443No
5SMNDC1SMNDC1
StanfordSource,  GeneCards
survival motor neuron domain containing 159450.057-0.3371No
6SF3B4SF3B4
StanfordSource,  GeneCards
splicing factor 3b, subunit 4, 49kDa60020.055-0.3325No
7PRPF18PRPF18
StanfordSource,  GeneCards
PRP18 pre-mRNA processing factor 18 homolog (yeast)61820.050-0.3368No
8NOL3NOL3
StanfordSource,  GeneCards
nucleolar protein 3 (apoptosis repressor with CARD domain)61910.050-0.3297No
9PRPF8PRPF8
StanfordSource,  GeneCards
PRP8 pre-mRNA processing factor 8 homolog (yeast)63930.044-0.3364No
10SNRPNSNRPN
StanfordSource,  GeneCards
small nuclear ribonucleoprotein polypeptide N71610.022-0.3842No
11NONONONO
StanfordSource,  GeneCards
non-POU domain containing, octamer-binding78040.001-0.4268No
12DDX23DDX23
StanfordSource,  GeneCards
DEAD (Asp-Glu-Ala-Asp) box polypeptide 2378130.001-0.4272No
13SFRS7SFRS7
StanfordSource,  GeneCards
splicing factor, arginine/serine-rich 7, 35kDa78410.000-0.4290No
14PPIGPPIG
StanfordSource,  GeneCards
peptidyl-prolyl isomerase G (cyclophilin G)7936-0.002-0.4349No
15SRRM1SRRM1
StanfordSource,  GeneCards
serine/arginine repetitive matrix 18063-0.006-0.4424No
16SNRPBSNRPB
StanfordSource,  GeneCards
small nuclear ribonucleoprotein polypeptides B and B18122-0.007-0.4453No
17SFRS2SFRS2
StanfordSource,  GeneCards
splicing factor, arginine/serine-rich 28158-0.008-0.4464No
18PPANPPAN
StanfordSource,  GeneCards
peter pan homolog (Drosophila)8439-0.016-0.4626No
19HNRPCHNRPC
StanfordSource,  GeneCards
heterogeneous nuclear ribonucleoprotein C (C1/C2)8679-0.022-0.4752No
20PRPF3PRPF3
StanfordSource,  GeneCards
PRP3 pre-mRNA processing factor 3 homolog (yeast)9973-0.060-0.5523No
21SNRPD3SNRPD3
StanfordSource,  GeneCards
small nuclear ribonucleoprotein D3 polypeptide 18kDa10382-0.073-0.5684No
22SNRPB2SNRPB2
StanfordSource,  GeneCards
small nuclear ribonucleoprotein polypeptide B''10812-0.087-0.5838Yes
23LSM1LSM1
StanfordSource,  GeneCards
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)10813-0.087-0.5706Yes
24SNRPD1SNRPD1
StanfordSource,  GeneCards
small nuclear ribonucleoprotein D1 polypeptide 16kDa10901-0.090-0.5627Yes
25PRPF4PRPF4
StanfordSource,  GeneCards
PRP4 pre-mRNA processing factor 4 homolog (yeast)11268-0.103-0.5714Yes
26SFRS4SFRS4
StanfordSource,  GeneCards
splicing factor, arginine/serine-rich 411441-0.109-0.5663Yes
27SF3B3SF3B3
StanfordSource,  GeneCards
splicing factor 3b, subunit 3, 130kDa11529-0.112-0.5550Yes
28SRP19SRP19
StanfordSource,  GeneCards
signal recognition particle 19kDa11542-0.112-0.5388Yes
29CDC40CDC40
StanfordSource,  GeneCards
cell division cycle 40 homolog (yeast)11617-0.115-0.5263Yes
30MPHOSPH10MPHOSPH10
StanfordSource,  GeneCards
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)11646-0.116-0.5105Yes
31SNRPGSNRPG
StanfordSource,  GeneCards
small nuclear ribonucleoprotein polypeptide G11874-0.124-0.5068Yes
32U2AF1U2AF1
StanfordSource,  GeneCards
U2(RNU2) small nuclear RNA auxiliary factor 111954-0.128-0.4927Yes
33SFRS2IPSFRS2IP
StanfordSource,  GeneCards
splicing factor, arginine/serine-rich 2, interacting protein12062-0.132-0.4798Yes
34LSM4LSM4
StanfordSource,  GeneCards
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)12169-0.136-0.4662Yes
35NCBP1NCBP1
StanfordSource,  GeneCards
nuclear cap binding protein subunit 1, 80kDa12199-0.137-0.4472Yes
36USP39USP39
StanfordSource,  GeneCards
ubiquitin specific protease 3912426-0.146-0.4400Yes
37SNRPD2SNRPD2
StanfordSource,  GeneCards
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa12477-0.149-0.4208Yes
38KHSRPKHSRP
StanfordSource,  GeneCards
KH-type splicing regulatory protein (FUSE binding protein 2)12726-0.159-0.4131Yes
39SFPQSFPQ
StanfordSource,  GeneCards
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)13200-0.182-0.4169Yes
40PTBP1PTBP1
StanfordSource,  GeneCards
polypyrimidine tract binding protein 113295-0.188-0.3946Yes
41SNRPFSNRPF
StanfordSource,  GeneCards
small nuclear ribonucleoprotein polypeptide F13348-0.191-0.3691Yes
42SFRS10SFRS10
StanfordSource,  GeneCards
splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila)13463-0.198-0.3466Yes
43SNRPA1SNRPA1
StanfordSource,  GeneCards
small nuclear ribonucleoprotein polypeptide A'13499-0.200-0.3185Yes
44SNRPCSNRPC
StanfordSource,  GeneCards
small nuclear ribonucleoprotein polypeptide C14052-0.240-0.3187Yes
45SF3A1SF3A1
StanfordSource,  GeneCards
splicing factor 3a, subunit 1, 120kDa14454-0.282-0.3025Yes
46FNBP3FNBP3
StanfordSource,  GeneCards
formin binding protein 314762-0.337-0.2718Yes
47SF3A2SF3A2
StanfordSource,  GeneCards
splicing factor 3a, subunit 2, 66kDa14805-0.344-0.2223Yes
48HPRP8BPHPRP8BP
StanfordSource,  GeneCards
U5 snRNP-specific 40 kDa protein (hPrp8-binding)15017-0.473-0.1644Yes
49LSM6LSM6
StanfordSource,  GeneCards
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)15023-0.481-0.0915Yes
50U2AF1L2U2AF1L2
StanfordSource,  GeneCards
U2(RNU2) small nuclear RNA auxiliary factor 1-like 215046-0.6160.0006Yes
Table: GSEA details [plain text format]



Fig 1: GSEA_Results   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List



Fig 2: Gender_collapsed.gct   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: Null Distribution for mRNA_splicing   
Histogram of random enrichment scores (real ES = -0.5970093 )