Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Gender_collapsed.gct |
| Phenotype | FEMALE |
| GeneSet | C2.symbols.gmt#mtorPathway |
| Enrichment Score (ES) | -0.5170458 |
| Normalized Enrichment Score (NES) | -1.370591 |
| Nominal p-value | 0.16788322 |
| FDR q-value | 0.9005321 |
| FWER p-Value | 0.87 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PDK2 | PDK2 StanfordSource, GeneCards | pyruvate dehydrogenase kinase, isoenzyme 2 | 752 | 0.300 | 0.0529 | No |
| 2 | FRAP1 | FRAP1 StanfordSource, GeneCards | FK506 binding protein 12-rapamycin associated protein 1 | 4841 | 0.091 | -0.1880 | No |
| 3 | PIK3R1 | PIK3R1 StanfordSource, GeneCards | phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 6094 | 0.052 | -0.2533 | No |
| 4 | EIF4EBP1 | EIF4EBP1 StanfordSource, GeneCards | eukaryotic translation initiation factor 4E binding protein 1 | 7488 | 0.011 | -0.3421 | No |
| 5 | MKNK1 | MKNK1 StanfordSource, GeneCards | MAP kinase-interacting serine/threonine kinase 1 | 7900 | -0.002 | -0.3689 | No |
| 6 | EIF4A1 | EIF4A1 StanfordSource, GeneCards | eukaryotic translation initiation factor 4A, isoform 1 | 8373 | -0.014 | -0.3954 | No |
| 7 | PIK3CA | PIK3CA StanfordSource, GeneCards | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 8760 | -0.024 | -0.4128 | No |
| 8 | EIF4G3 | EIF4G3 StanfordSource, GeneCards | eukaryotic translation initiation factor 4 gamma, 3 | 9174 | -0.036 | -0.4281 | No |
| 9 | EIF3S10 | EIF3S10 StanfordSource, GeneCards | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa | 9469 | -0.045 | -0.4322 | No |
| 10 | PDPK1 | PDPK1 StanfordSource, GeneCards | 3-phosphoinositide dependent protein kinase-1 | 10667 | -0.082 | -0.4837 | No |
| 11 | EIF4G1 | EIF4G1 StanfordSource, GeneCards | eukaryotic translation initiation factor 4 gamma, 1 | 11170 | -0.100 | -0.4828 | Yes |
| 12 | EIF4A2 | EIF4A2 StanfordSource, GeneCards | eukaryotic translation initiation factor 4A, isoform 2 | 11196 | -0.101 | -0.4499 | Yes |
| 13 | EIF4B | EIF4B StanfordSource, GeneCards | eukaryotic translation initiation factor 4B | 11316 | -0.105 | -0.4219 | Yes |
| 14 | RPS6 | RPS6 StanfordSource, GeneCards | ribosomal protein S6 | 11496 | -0.111 | -0.3957 | Yes |
| 15 | PTEN | PTEN StanfordSource, GeneCards | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | 12952 | -0.170 | -0.4342 | Yes |
| 16 | EIF4E | EIF4E StanfordSource, GeneCards | eukaryotic translation initiation factor 4E | 13011 | -0.173 | -0.3789 | Yes |
| 17 | TSC2 | TSC2 StanfordSource, GeneCards | tuberous sclerosis 2 | 13050 | -0.175 | -0.3215 | Yes |
| 18 | AKT1 | AKT1 StanfordSource, GeneCards | v-akt murine thymoma viral oncogene homolog 1 | 13061 | -0.175 | -0.2621 | Yes |
| 19 | RPS6KB1 | RPS6KB1 StanfordSource, GeneCards | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 13156 | -0.180 | -0.2068 | Yes |
| 20 | EIF4G2 | EIF4G2 StanfordSource, GeneCards | eukaryotic translation initiation factor 4 gamma, 2 | 13385 | -0.193 | -0.1557 | Yes |
| 21 | FKBP1A | FKBP1A StanfordSource, GeneCards | FK506 binding protein 1A, 12kDa | 14183 | -0.251 | -0.1227 | Yes |
| 22 | TSC1 | TSC1 StanfordSource, GeneCards | tuberous sclerosis 1 | 14212 | -0.254 | -0.0376 | Yes |
| 23 | PPP2CA | PPP2CA StanfordSource, GeneCards | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 14388 | -0.273 | 0.0444 | Yes |
