Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | p53_full_useme_maxed_cs.gct |
| Phenotype | MUT |
| GeneSet | s2.symbols.gmt#BRCA_UP |
| Enrichment Score (ES) | -0.4606577 |
| Normalized Enrichment Score (NES) | -1.5834424 |
| Nominal p-value | 0.025408348 |
| FDR q-value | 0.5200231 |
| FWER p-Value | 0.891 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PBP | PBP StanfordSource, GeneCards | prostatic binding protein | 510 | 0.296 | 0.0048 | No |
| 2 | IL16 | IL16 StanfordSource, GeneCards | interleukin 16 (lymphocyte chemoattractant factor) | 2015 | 0.174 | -0.1121 | No |
| 3 | STAT1 | STAT1 StanfordSource, GeneCards | signal transducer and activator of transcription 1, 91kDa | 2296 | 0.157 | -0.1104 | No |
| 4 | TSNAX | TSNAX StanfordSource, GeneCards | translin-associated factor X | 2551 | 0.144 | -0.1087 | No |
| 5 | IDH1 | IDH1 StanfordSource, GeneCards | isocitrate dehydrogenase 1 (NADP+), soluble | 3080 | 0.117 | -0.1391 | No |
| 6 | TFPI2 | TFPI2 StanfordSource, GeneCards | tissue factor pathway inhibitor 2 | 3616 | 0.092 | -0.1751 | No |
| 7 | LAMA3 | LAMA3 StanfordSource, GeneCards | laminin, alpha 3 | 3705 | 0.088 | -0.1673 | No |
| 8 | ADD1 | ADD1 StanfordSource, GeneCards | adducin 1 (alpha) | 4030 | 0.073 | -0.1858 | No |
| 9 | PPP1R1A | PPP1R1A StanfordSource, GeneCards | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 4086 | 0.071 | -0.1781 | No |
| 10 | MGAT2 | MGAT2 StanfordSource, GeneCards | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 4322 | 0.060 | -0.1902 | No |
| 11 | P2RX1 | P2RX1 StanfordSource, GeneCards | purinergic receptor P2X, ligand-gated ion channel, 1 | 4810 | 0.039 | -0.2313 | No |
| 12 | GALNT3 | GALNT3 StanfordSource, GeneCards | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) | 5526 | 0.009 | -0.3008 | No |
| 13 | JAK1 | JAK1 StanfordSource, GeneCards | Janus kinase 1 (a protein tyrosine kinase) | 5657 | 0.002 | -0.3133 | No |
| 14 | KCNK1 | KCNK1 StanfordSource, GeneCards | potassium channel, subfamily K, member 1 | 5908 | -0.009 | -0.3364 | No |
| 15 | LIMS1 | LIMS1 StanfordSource, GeneCards | LIM and senescent cell antigen-like domains 1 | 6212 | -0.023 | -0.3622 | No |
| 16 | CITED2 | CITED2 StanfordSource, GeneCards | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 6304 | -0.028 | -0.3660 | No |
| 17 | NFYC | NFYC StanfordSource, GeneCards | nuclear transcription factor Y, gamma | 6348 | -0.030 | -0.3648 | No |
| 18 | RRM2 | RRM2 StanfordSource, GeneCards | ribonucleotide reductase M2 polypeptide | 6968 | -0.060 | -0.4151 | No |
| 19 | SERPINB1 | SERPINB1 StanfordSource, GeneCards | serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 | 7046 | -0.064 | -0.4107 | No |
| 20 | ID4 | ID4 StanfordSource, GeneCards | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 7231 | -0.072 | -0.4154 | No |
| 21 | APP | APP StanfordSource, GeneCards | amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) | 7368 | -0.080 | -0.4139 | No |
| 22 | CALD1 | CALD1 StanfordSource, GeneCards | caldesmon 1 | 7396 | -0.082 | -0.4013 | No |
| 23 | SEPP1 | SEPP1 StanfordSource, GeneCards | selenoprotein P, plasma, 1 | 7994 | -0.114 | -0.4393 | Yes |
| 24 | ZNF148 | ZNF148 StanfordSource, GeneCards | zinc finger protein 148 (pHZ-52) | 8060 | -0.117 | -0.4238 | Yes |
| 25 | WRB | WRB StanfordSource, GeneCards | tryptophan rich basic protein | 8096 | -0.120 | -0.4048 | Yes |
| 26 | STC1 | STC1 StanfordSource, GeneCards | stanniocalcin 1 | 8109 | -0.120 | -0.3834 | Yes |
| 27 | ENPP2 | ENPP2 StanfordSource, GeneCards | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 8112 | -0.121 | -0.3610 | Yes |
| 28 | SEC23A | SEC23A StanfordSource, GeneCards | Sec23 homolog A (S. cerevisiae) | 8162 | -0.125 | -0.3424 | Yes |
| 29 | KIF2 | KIF2 StanfordSource, GeneCards | kinesin heavy chain member 2 | 8335 | -0.137 | -0.3338 | Yes |
| 30 | CLTB | CLTB StanfordSource, GeneCards | clathrin, light polypeptide (Lcb) | 8572 | -0.153 | -0.3285 | Yes |
| 31 | EXTL2 | EXTL2 StanfordSource, GeneCards | exostoses (multiple)-like 2 | 8609 | -0.156 | -0.3028 | Yes |
| 32 | H1F0 | H1F0 StanfordSource, GeneCards | H1 histone family, member 0 | 8914 | -0.177 | -0.2998 | Yes |
| 33 | LIPA | LIPA StanfordSource, GeneCards | lipase A, lysosomal acid, cholesterol esterase (Wolman disease) | 9317 | -0.211 | -0.3001 | Yes |
| 34 | CCNG2 | CCNG2 StanfordSource, GeneCards | cyclin G2 | 9354 | -0.216 | -0.2632 | Yes |
| 35 | RDX | RDX StanfordSource, GeneCards | radixin | 9664 | -0.258 | -0.2454 | Yes |
| 36 | TITF1 | TITF1 StanfordSource, GeneCards | thyroid transcription factor 1 | 9986 | -0.347 | -0.2123 | Yes |
| 37 | HTATIP | HTATIP StanfordSource, GeneCards | HIV-1 Tat interactive protein, 60kDa | 10002 | -0.356 | -0.1471 | Yes |
| 38 | MAP2K1 | MAP2K1 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 1 | 10067 | -0.410 | -0.0766 | Yes |
| 39 | VAMP3 | VAMP3 StanfordSource, GeneCards | vesicle-associated membrane protein 3 (cellubrevin) | 10073 | -0.425 | 0.0026 | Yes |
