Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | p53_full_useme_maxed_cs.gct |
| Phenotype | WT |
| GeneSet | s2.symbols.gmt#HTERT_DOWN |
| Enrichment Score (ES) | 0.3427992 |
| Normalized Enrichment Score (NES) | 1.3177729 |
| Nominal p-value | 0.110526316 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | STAT4 | STAT4 StanfordSource, GeneCards | signal transducer and activator of transcription 4 | 31 | 0.480 | 0.0500 | Yes |
| 2 | PML | PML StanfordSource, GeneCards | promyelocytic leukemia | 73 | 0.420 | 0.0923 | Yes |
| 3 | CALML3 | CALML3 StanfordSource, GeneCards | calmodulin-like 3 | 119 | 0.392 | 0.1313 | Yes |
| 4 | TNFSF9 | TNFSF9 StanfordSource, GeneCards | tumor necrosis factor (ligand) superfamily, member 9 | 169 | 0.372 | 0.1675 | Yes |
| 5 | KYNU | KYNU StanfordSource, GeneCards | kynureninase (L-kynurenine hydrolase) | 395 | 0.315 | 0.1799 | Yes |
| 6 | ACLY | ACLY StanfordSource, GeneCards | ATP citrate lyase | 676 | 0.274 | 0.1823 | Yes |
| 7 | RAB40B | RAB40B StanfordSource, GeneCards | RAB40B, member RAS oncogene family | 857 | 0.253 | 0.1923 | Yes |
| 8 | PTPNS1 | PTPNS1 StanfordSource, GeneCards | protein tyrosine phosphatase, non-receptor type substrate 1 | 1008 | 0.241 | 0.2040 | Yes |
| 9 | GSTO1 | GSTO1 StanfordSource, GeneCards | glutathione S-transferase omega 1 | 1117 | 0.232 | 0.2189 | Yes |
| 10 | UNC119 | UNC119 StanfordSource, GeneCards | unc-119 homolog (C. elegans) | 1185 | 0.227 | 0.2374 | Yes |
| 11 | NME4 | NME4 StanfordSource, GeneCards | non-metastatic cells 4, protein expressed in | 1201 | 0.226 | 0.2609 | Yes |
| 12 | AKR1C3 | AKR1C3 StanfordSource, GeneCards | aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) | 1215 | 0.226 | 0.2846 | Yes |
| 13 | PON2 | PON2 StanfordSource, GeneCards | paraoxonase 2 | 1432 | 0.212 | 0.2865 | Yes |
| 14 | GAMT | GAMT StanfordSource, GeneCards | guanidinoacetate N-methyltransferase | 1585 | 0.200 | 0.2935 | Yes |
| 15 | VAV2 | VAV2 StanfordSource, GeneCards | vav 2 oncogene | 1595 | 0.200 | 0.3147 | Yes |
| 16 | APEG1 | APEG1 StanfordSource, GeneCards | aortic preferentially expressed protein 1 | 2143 | 0.166 | 0.2785 | Yes |
| 17 | GM2A | GM2A StanfordSource, GeneCards | GM2 ganglioside activator protein | 2250 | 0.159 | 0.2856 | Yes |
| 18 | AHCY | AHCY StanfordSource, GeneCards | S-adenosylhomocysteine hydrolase | 2355 | 0.154 | 0.2923 | Yes |
| 19 | KIAA0140 | KIAA0140 StanfordSource, GeneCards | KIAA0140 gene product | 2436 | 0.150 | 0.3009 | Yes |
| 20 | ANXA4 | ANXA4 StanfordSource, GeneCards | annexin A4 | 2481 | 0.147 | 0.3128 | Yes |
| 21 | PIK3R3 | PIK3R3 StanfordSource, GeneCards | phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma) | 2509 | 0.146 | 0.3263 | Yes |
| 22 | FAH | FAH StanfordSource, GeneCards | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 2646 | 0.138 | 0.3280 | Yes |
| 23 | ASAH1 | ASAH1 StanfordSource, GeneCards | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 2657 | 0.138 | 0.3423 | Yes |
| 24 | ANKRD15 | ANKRD15 StanfordSource, GeneCards | ankyrin repeat domain 15 | 2958 | 0.123 | 0.3261 | Yes |
| 25 | XRCC5 | XRCC5 StanfordSource, GeneCards | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 2971 | 0.123 | 0.3384 | Yes |
| 26 | PCNA | PCNA StanfordSource, GeneCards | proliferating cell nuclear antigen | 3090 | 0.117 | 0.3396 | Yes |
| 27 | AKT1 | AKT1 StanfordSource, GeneCards | v-akt murine thymoma viral oncogene homolog 1 | 3184 | 0.112 | 0.3428 | Yes |
| 28 | SAA1 | SAA1 StanfordSource, GeneCards | serum amyloid A1 | 3404 | 0.102 | 0.3323 | No |
| 29 | PCOLN3 | PCOLN3 StanfordSource, GeneCards | procollagen (type III) N-endopeptidase | 3609 | 0.092 | 0.3221 | No |
| 30 | PPP1R7 | PPP1R7 StanfordSource, GeneCards | protein phosphatase 1, regulatory subunit 7 | 3760 | 0.085 | 0.3166 | No |
| 31 | TRADD | TRADD StanfordSource, GeneCards | TNFRSF1A-associated via death domain | 3802 | 0.084 | 0.3218 | No |
| 32 | GSN | GSN StanfordSource, GeneCards | gelsolin (amyloidosis, Finnish type) | 3962 | 0.076 | 0.3143 | No |
| 33 | FOSB | FOSB StanfordSource, GeneCards | FBJ murine osteosarcoma viral oncogene homolog B | 3975 | 0.075 | 0.3214 | No |
| 34 | DHCR24 | DHCR24 StanfordSource, GeneCards | 24-dehydrocholesterol reductase | 4658 | 0.046 | 0.2585 | No |
| 35 | ARHGDIB | ARHGDIB StanfordSource, GeneCards | Rho GDP dissociation inhibitor (GDI) beta | 4964 | 0.032 | 0.2317 | No |
| 36 | RRAGA | RRAGA StanfordSource, GeneCards | Ras-related GTP binding A | 5183 | 0.023 | 0.2125 | No |
| 37 | ABR | ABR StanfordSource, GeneCards | active BCR-related gene | 5226 | 0.021 | 0.2107 | No |
| 38 | PAM | PAM StanfordSource, GeneCards | peptidylglycine alpha-amidating monooxygenase | 5241 | 0.021 | 0.2116 | No |
| 39 | TUBB4 | TUBB4 StanfordSource, GeneCards | tubulin, beta, 4 | 5453 | 0.012 | 0.1918 | No |
| 40 | PGF | PGF StanfordSource, GeneCards | placental growth factor, vascular endothelial growth factor-related protein | 5635 | 0.003 | 0.1742 | No |
| 41 | IDI1 | IDI1 StanfordSource, GeneCards | isopentenyl-diphosphate delta isomerase | 5641 | 0.003 | 0.1740 | No |
| 42 | CCNG1 | CCNG1 StanfordSource, GeneCards | cyclin G1 | 5829 | -0.005 | 0.1559 | No |
| 43 | NID2 | NID2 StanfordSource, GeneCards | nidogen 2 (osteonidogen) | 6343 | -0.029 | 0.1080 | No |
| 44 | DNA2L | DNA2L StanfordSource, GeneCards | DNA2 DNA replication helicase 2-like (yeast) | 6346 | -0.029 | 0.1111 | No |
| 45 | POU5F1 | POU5F1 StanfordSource, GeneCards | POU domain, class 5, transcription factor 1 | 6432 | -0.034 | 0.1063 | No |
| 46 | UGP2 | UGP2 StanfordSource, GeneCards | UDP-glucose pyrophosphorylase 2 | 6499 | -0.037 | 0.1038 | No |
| 47 | SORD | SORD StanfordSource, GeneCards | sorbitol dehydrogenase | 6836 | -0.053 | 0.0762 | No |
| 48 | DUSP6 | DUSP6 StanfordSource, GeneCards | dual specificity phosphatase 6 | 6981 | -0.060 | 0.0685 | No |
| 49 | ATP5O | ATP5O StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 7079 | -0.065 | 0.0661 | No |
| 50 | ALDH3A2 | ALDH3A2 StanfordSource, GeneCards | aldehyde dehydrogenase 3 family, member A2 | 7163 | -0.069 | 0.0654 | No |
| 51 | TAGLN | TAGLN StanfordSource, GeneCards | transgelin | 7167 | -0.069 | 0.0728 | No |
| 52 | TCF4 | TCF4 StanfordSource, GeneCards | transcription factor 4 | 7222 | -0.072 | 0.0754 | No |
| 53 | CD47 | CD47 StanfordSource, GeneCards | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | 7831 | -0.106 | 0.0265 | No |
| 54 | SERPING1 | SERPING1 StanfordSource, GeneCards | serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | 7856 | -0.107 | 0.0359 | No |
| 55 | HEAB | HEAB StanfordSource, GeneCards | ATP/GTP-binding protein | 8141 | -0.123 | 0.0212 | No |
| 56 | IL1RN | IL1RN StanfordSource, GeneCards | interleukin 1 receptor antagonist | 8247 | -0.132 | 0.0253 | No |
| 57 | CBR1 | CBR1 StanfordSource, GeneCards | carbonyl reductase 1 | 8276 | -0.134 | 0.0373 | No |
| 58 | TNFSF10 | TNFSF10 StanfordSource, GeneCards | tumor necrosis factor (ligand) superfamily, member 10 | 8285 | -0.134 | 0.0514 | No |
| 59 | EHHADH | EHHADH StanfordSource, GeneCards | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 8622 | -0.157 | 0.0353 | No |
| 60 | ALDH7A1 | ALDH7A1 StanfordSource, GeneCards | aldehyde dehydrogenase 7 family, member A1 | 8637 | -0.158 | 0.0514 | No |
| 61 | TST | TST StanfordSource, GeneCards | thiosulfate sulfurtransferase (rhodanese) | 8934 | -0.178 | 0.0417 | No |
| 62 | SRD5A1 | SRD5A1 StanfordSource, GeneCards | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 9145 | -0.196 | 0.0425 | No |
| 63 | RAB11A | RAB11A StanfordSource, GeneCards | RAB11A, member RAS oncogene family | 9339 | -0.214 | 0.0469 | No |
| 64 | VSNL1 | VSNL1 StanfordSource, GeneCards | visinin-like 1 | 9671 | -0.260 | 0.0426 | No |
