Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | p53_full_useme_maxed_cs.gct |
| Phenotype | MUT |
| GeneSet | s2.symbols.gmt#SA_B_CELL_RECEPTOR_COMPLEXES |
| Enrichment Score (ES) | -0.4482273 |
| Normalized Enrichment Score (NES) | -1.5750818 |
| Nominal p-value | 0.018823529 |
| FDR q-value | 0.49631584 |
| FWER p-Value | 0.904 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PAPPA | PAPPA StanfordSource, GeneCards | pregnancy-associated plasma protein A | 856 | 0.253 | -0.0093 | No |
| 2 | VAV2 | VAV2 StanfordSource, GeneCards | vav 2 oncogene | 1595 | 0.200 | -0.0227 | No |
| 3 | VAV1 | VAV1 StanfordSource, GeneCards | vav 1 oncogene | 1817 | 0.185 | 0.0110 | No |
| 4 | MAPK3 | MAPK3 StanfordSource, GeneCards | mitogen-activated protein kinase 3 | 2905 | 0.125 | -0.0594 | No |
| 5 | MAPK8IP3 | MAPK8IP3 StanfordSource, GeneCards | mitogen-activated protein kinase 8 interacting protein 3 | 3128 | 0.115 | -0.0469 | No |
| 6 | GRB2 | GRB2 StanfordSource, GeneCards | growth factor receptor-bound protein 2 | 4102 | 0.070 | -0.1226 | No |
| 7 | LYN | LYN StanfordSource, GeneCards | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 4984 | 0.031 | -0.2007 | No |
| 8 | JUN | JUN StanfordSource, GeneCards | v-jun sarcoma virus 17 oncogene homolog (avian) | 5283 | 0.019 | -0.2244 | No |
| 9 | BLNK | BLNK StanfordSource, GeneCards | B-cell linker | 5456 | 0.012 | -0.2380 | No |
| 10 | RPS6KA1 | RPS6KA1 StanfordSource, GeneCards | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 5571 | 0.006 | -0.2474 | No |
| 11 | SHC1 | SHC1 StanfordSource, GeneCards | SHC (Src homology 2 domain containing) transforming protein 1 | 6401 | -0.032 | -0.3201 | No |
| 12 | HRAS | HRAS StanfordSource, GeneCards | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 7563 | -0.090 | -0.4082 | No |
| 13 | ATF2 | ATF2 StanfordSource, GeneCards | activating transcription factor 2 | 7967 | -0.112 | -0.4146 | Yes |
| 14 | SOS1 | SOS1 StanfordSource, GeneCards | son of sevenless homolog 1 (Drosophila) | 8043 | -0.116 | -0.3871 | Yes |
| 15 | MAPK1 | MAPK1 StanfordSource, GeneCards | mitogen-activated protein kinase 1 | 8361 | -0.139 | -0.3770 | Yes |
| 16 | RPS6KA3 | RPS6KA3 StanfordSource, GeneCards | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 8418 | -0.143 | -0.3397 | Yes |
| 17 | BCR | BCR StanfordSource, GeneCards | breakpoint cluster region | 8525 | -0.150 | -0.3052 | Yes |
| 18 | FOS | FOS StanfordSource, GeneCards | v-fos FBJ murine osteosarcoma viral oncogene homolog | 8716 | -0.163 | -0.2752 | Yes |
| 19 | MAP3K1 | MAP3K1 StanfordSource, GeneCards | mitogen-activated protein kinase kinase kinase 1 | 8906 | -0.177 | -0.2410 | Yes |
| 20 | ELK1 | ELK1 StanfordSource, GeneCards | ELK1, member of ETS oncogene family | 9250 | -0.205 | -0.2136 | Yes |
| 21 | RAC1 | RAC1 StanfordSource, GeneCards | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 9657 | -0.258 | -0.1767 | Yes |
| 22 | SYK | SYK StanfordSource, GeneCards | spleen tyrosine kinase | 9936 | -0.325 | -0.1067 | Yes |
| 23 | MAP2K1 | MAP2K1 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 1 | 10067 | -0.410 | 0.0032 | Yes |
