Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | p53_full_useme_maxed_cs.gct |
| Phenotype | WT |
| GeneSet | s2.symbols.gmt#ca_nf_at_signalling |
| Enrichment Score (ES) | 0.32990462 |
| Normalized Enrichment Score (NES) | 1.2849063 |
| Nominal p-value | 0.13381556 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDKN1A | CDKN1A StanfordSource, GeneCards | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0 | 0.843 | 0.0541 | Yes |
| 2 | IFNA1 | IFNA1 StanfordSource, GeneCards | interferon, alpha 1 | 48 | 0.451 | 0.0784 | Yes |
| 3 | BCL2 | BCL2 StanfordSource, GeneCards | B-cell CLL/lymphoma 2 | 71 | 0.420 | 0.1031 | Yes |
| 4 | NFATC1 | NFATC1 StanfordSource, GeneCards | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | 103 | 0.400 | 0.1257 | Yes |
| 5 | P2RX7 | P2RX7 StanfordSource, GeneCards | purinergic receptor P2X, ligand-gated ion channel, 7 | 129 | 0.389 | 0.1482 | Yes |
| 6 | IL4 | IL4 StanfordSource, GeneCards | interleukin 4 | 206 | 0.354 | 0.1633 | Yes |
| 7 | TNF | TNF StanfordSource, GeneCards | tumor necrosis factor (TNF superfamily, member 2) | 264 | 0.340 | 0.1794 | Yes |
| 8 | MAP2K7 | MAP2K7 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 7 | 465 | 0.304 | 0.1790 | Yes |
| 9 | MEF2D | MEF2D StanfordSource, GeneCards | MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) | 472 | 0.303 | 0.1978 | Yes |
| 10 | CAMK2B | CAMK2B StanfordSource, GeneCards | calcium/calmodulin-dependent protein kinase (CaM kinase) II beta | 514 | 0.295 | 0.2127 | Yes |
| 11 | OPRD1 | OPRD1 StanfordSource, GeneCards | opioid receptor, delta 1 | 689 | 0.272 | 0.2127 | Yes |
| 12 | TNFSF5 | TNFSF5 StanfordSource, GeneCards | tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome) | 703 | 0.270 | 0.2288 | Yes |
| 13 | ICOS | ICOS StanfordSource, GeneCards | inducible T-cell co-stimulator | 818 | 0.257 | 0.2339 | Yes |
| 14 | GAPD | GAPD StanfordSource, GeneCards | glyceraldehyde-3-phosphate dehydrogenase | 823 | 0.257 | 0.2499 | Yes |
| 15 | IFNB1 | IFNB1 StanfordSource, GeneCards | interferon, beta 1, fibroblast | 905 | 0.249 | 0.2578 | Yes |
| 16 | CD3Z | CD3Z StanfordSource, GeneCards | CD3Z antigen, zeta polypeptide (TiT3 complex) | 1238 | 0.224 | 0.2390 | Yes |
| 17 | EGR3 | EGR3 StanfordSource, GeneCards | early growth response 3 | 1366 | 0.216 | 0.2402 | Yes |
| 18 | IL1B | IL1B StanfordSource, GeneCards | interleukin 1, beta | 1396 | 0.214 | 0.2510 | Yes |
| 19 | NCK2 | NCK2 StanfordSource, GeneCards | NCK adaptor protein 2 | 1427 | 0.212 | 0.2616 | Yes |
| 20 | CABIN1 | CABIN1 StanfordSource, GeneCards | calcineurin binding protein 1 | 1514 | 0.205 | 0.2662 | Yes |
| 21 | VAV2 | VAV2 StanfordSource, GeneCards | vav 2 oncogene | 1595 | 0.200 | 0.2710 | Yes |
| 22 | GATA4 | GATA4 StanfordSource, GeneCards | GATA binding protein 4 | 1682 | 0.194 | 0.2749 | Yes |
| 23 | IFNG | IFNG StanfordSource, GeneCards | interferon, gamma | 1741 | 0.191 | 0.2813 | Yes |
| 24 | IL2 | IL2 StanfordSource, GeneCards | interleukin 2 | 1791 | 0.187 | 0.2885 | Yes |
| 25 | VAV1 | VAV1 StanfordSource, GeneCards | vav 1 oncogene | 1817 | 0.185 | 0.2979 | Yes |
| 26 | PPIA | PPIA StanfordSource, GeneCards | peptidylprolyl isomerase A (cyclophilin A) | 1881 | 0.182 | 0.3033 | Yes |
| 27 | PPP3R1 | PPP3R1 StanfordSource, GeneCards | protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I) | 1898 | 0.181 | 0.3133 | Yes |
| 28 | SLA | SLA StanfordSource, GeneCards | Src-like-adaptor | 1916 | 0.180 | 0.3231 | Yes |
| 29 | CAMK4 | CAMK4 StanfordSource, GeneCards | calcium/calmodulin-dependent protein kinase IV | 1963 | 0.177 | 0.3299 | Yes |
| 30 | ITK | ITK StanfordSource, GeneCards | IL2-inducible T-cell kinase | 2226 | 0.161 | 0.3141 | No |
| 31 | CD3E | CD3E StanfordSource, GeneCards | CD3E antigen, epsilon polypeptide (TiT3 complex) | 2294 | 0.157 | 0.3175 | No |
| 32 | MEF2B | MEF2B StanfordSource, GeneCards | MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B) | 2505 | 0.146 | 0.3059 | No |
| 33 | JUNB | JUNB StanfordSource, GeneCards | jun B proto-oncogene | 2527 | 0.145 | 0.3131 | No |
| 34 | IL3 | IL3 StanfordSource, GeneCards | interleukin 3 (colony-stimulating factor, multiple) | 2651 | 0.138 | 0.3097 | No |
| 35 | RPL13A | RPL13A StanfordSource, GeneCards | ribosomal protein L13a | 2766 | 0.132 | 0.3068 | No |
| 36 | PTPRC | PTPRC StanfordSource, GeneCards | protein tyrosine phosphatase, receptor type, C | 2885 | 0.126 | 0.3031 | No |
| 37 | IL10 | IL10 StanfordSource, GeneCards | interleukin 10 | 3211 | 0.111 | 0.2777 | No |
| 38 | GSK3B | GSK3B StanfordSource, GeneCards | glycogen synthase kinase 3 beta | 3246 | 0.109 | 0.2813 | No |
| 39 | MEF2A | MEF2A StanfordSource, GeneCards | MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) | 3392 | 0.103 | 0.2734 | No |
| 40 | IL2RA | IL2RA StanfordSource, GeneCards | interleukin 2 receptor, alpha | 3563 | 0.095 | 0.2625 | No |
| 41 | GSK3A | GSK3A StanfordSource, GeneCards | glycogen synthase kinase 3 alpha | 3725 | 0.087 | 0.2520 | No |
| 42 | FLJ14639 | FLJ14639 StanfordSource, GeneCards | hypothetical protein FLJ14639 | 3759 | 0.085 | 0.2542 | No |
| 43 | CD3G | CD3G StanfordSource, GeneCards | CD3G antigen, gamma polypeptide (TiT3 complex) | 4050 | 0.072 | 0.2298 | No |
| 44 | FCER1A | FCER1A StanfordSource, GeneCards | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 4077 | 0.071 | 0.2318 | No |
| 45 | GATA3 | GATA3 StanfordSource, GeneCards | GATA binding protein 3 | 4103 | 0.070 | 0.2337 | No |
| 46 | CREBBP | CREBBP StanfordSource, GeneCards | CREB binding protein (Rubinstein-Taybi syndrome) | 4356 | 0.059 | 0.2123 | No |
| 47 | IL8 | IL8 StanfordSource, GeneCards | interleukin 8 | 4421 | 0.056 | 0.2095 | No |
| 48 | PIN1 | PIN1 StanfordSource, GeneCards | protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 | 4532 | 0.052 | 0.2019 | No |
| 49 | CD69 | CD69 StanfordSource, GeneCards | CD69 antigen (p60, early T-cell activation antigen) | 4544 | 0.051 | 0.2040 | No |
| 50 | NFKBIB | NFKBIB StanfordSource, GeneCards | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 4651 | 0.046 | 0.1964 | No |
| 51 | NFKBIE | NFKBIE StanfordSource, GeneCards | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 5018 | 0.030 | 0.1617 | No |
| 52 | KPNA5 | KPNA5 StanfordSource, GeneCards | karyopherin alpha 5 (importin alpha 6) | 5154 | 0.024 | 0.1498 | No |
| 53 | IL8RA | IL8RA StanfordSource, GeneCards | interleukin 8 receptor, alpha | 5239 | 0.021 | 0.1427 | No |
| 54 | FCGR3A | FCGR3A StanfordSource, GeneCards | Fc fragment of IgG, low affinity IIIa, receptor for (CD16) | 5492 | 0.010 | 0.1182 | No |
| 55 | IL13 | IL13 StanfordSource, GeneCards | interleukin 13 | 5738 | -0.001 | 0.0938 | No |
| 56 | SP3 | SP3 StanfordSource, GeneCards | Sp3 transcription factor | 5757 | -0.002 | 0.0921 | No |
| 57 | MYF5 | MYF5 StanfordSource, GeneCards | myogenic factor 5 | 5941 | -0.010 | 0.0745 | No |
| 58 | NFATC4 | NFATC4 StanfordSource, GeneCards | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 6114 | -0.019 | 0.0585 | No |
| 59 | TNFSF6 | TNFSF6 StanfordSource, GeneCards | tumor necrosis factor (ligand) superfamily, member 6 | 6238 | -0.024 | 0.0478 | No |
| 60 | CEBPB | CEBPB StanfordSource, GeneCards | CCAAT/enhancer binding protein (C/EBP), beta | 6519 | -0.037 | 0.0222 | No |
| 61 | NPPB | NPPB StanfordSource, GeneCards | natriuretic peptide precursor B | 6875 | -0.055 | -0.0097 | No |
| 62 | NUP214 | NUP214 StanfordSource, GeneCards | nucleoporin 214kDa | 6882 | -0.055 | -0.0068 | No |
| 63 | CALM1 | CALM1 StanfordSource, GeneCards | calmodulin 1 (phosphorylase kinase, delta) | 6929 | -0.058 | -0.0077 | No |
| 64 | NFAT5 | NFAT5 StanfordSource, GeneCards | nuclear factor of activated T-cells 5, tonicity-responsive | 7071 | -0.065 | -0.0176 | No |
| 65 | TRAF2 | TRAF2 StanfordSource, GeneCards | TNF receptor-associated factor 2 | 7348 | -0.079 | -0.0401 | No |
| 66 | FKBP1B | FKBP1B StanfordSource, GeneCards | FK506 binding protein 1B, 12.6 kDa | 7379 | -0.081 | -0.0379 | No |
| 67 | HRAS | HRAS StanfordSource, GeneCards | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 7563 | -0.090 | -0.0504 | No |
| 68 | BAD | BAD StanfordSource, GeneCards | BCL2-antagonist of cell death | 7728 | -0.099 | -0.0604 | No |
| 69 | SP1 | SP1 StanfordSource, GeneCards | Sp1 transcription factor | 7738 | -0.100 | -0.0549 | No |
| 70 | TGFB1 | TGFB1 StanfordSource, GeneCards | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 7814 | -0.105 | -0.0557 | No |
| 71 | PPP3CC | PPP3CC StanfordSource, GeneCards | protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) | 7825 | -0.105 | -0.0499 | No |
| 72 | GRLF1 | GRLF1 StanfordSource, GeneCards | glucocorticoid receptor DNA binding factor 1 | 7874 | -0.108 | -0.0478 | No |
| 73 | MAPK8 | MAPK8 StanfordSource, GeneCards | mitogen-activated protein kinase 8 | 7956 | -0.112 | -0.0487 | No |
| 74 | ACTB | ACTB StanfordSource, GeneCards | actin, beta | 7993 | -0.114 | -0.0450 | No |
| 75 | CSF2 | CSF2 StanfordSource, GeneCards | colony stimulating factor 2 (granulocyte-macrophage) | 8002 | -0.114 | -0.0385 | No |
| 76 | IL6 | IL6 StanfordSource, GeneCards | interleukin 6 (interferon, beta 2) | 8024 | -0.115 | -0.0332 | No |
| 77 | EGR2 | EGR2 StanfordSource, GeneCards | early growth response 2 (Krox-20 homolog, Drosophila) | 8042 | -0.116 | -0.0274 | No |
| 78 | CALM3 | CALM3 StanfordSource, GeneCards | calmodulin 3 (phosphorylase kinase, delta) | 8068 | -0.118 | -0.0223 | No |
| 79 | TRPV6 | TRPV6 StanfordSource, GeneCards | transient receptor potential cation channel, subfamily V, member 6 | 8125 | -0.122 | -0.0201 | No |
| 80 | CSNK2A1 | CSNK2A1 StanfordSource, GeneCards | casein kinase 2, alpha 1 polypeptide | 8167 | -0.125 | -0.0162 | No |
| 81 | FOSL1 | FOSL1 StanfordSource, GeneCards | FOS-like antigen 1 | 8223 | -0.129 | -0.0134 | No |
| 82 | MAPK14 | MAPK14 StanfordSource, GeneCards | mitogen-activated protein kinase 14 | 8605 | -0.156 | -0.0414 | No |
| 83 | FOS | FOS StanfordSource, GeneCards | v-fos FBJ murine osteosarcoma viral oncogene homolog | 8716 | -0.163 | -0.0420 | No |
| 84 | CSNK2B | CSNK2B StanfordSource, GeneCards | casein kinase 2, beta polypeptide | 8855 | -0.173 | -0.0447 | No |
| 85 | MAPK9 | MAPK9 StanfordSource, GeneCards | mitogen-activated protein kinase 9 | 8908 | -0.177 | -0.0385 | No |
| 86 | SFN | SFN StanfordSource, GeneCards | stratifin | 9070 | -0.190 | -0.0424 | No |
| 87 | NFATC3 | NFATC3 StanfordSource, GeneCards | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 9112 | -0.193 | -0.0341 | No |
| 88 | CALM2 | CALM2 StanfordSource, GeneCards | calmodulin 2 (phosphorylase kinase, delta) | 9251 | -0.205 | -0.0347 | No |
| 89 | PAK1 | PAK1 StanfordSource, GeneCards | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 9376 | -0.218 | -0.0331 | No |
| 90 | NFKB2 | NFKB2 StanfordSource, GeneCards | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 9443 | -0.226 | -0.0252 | No |
| 91 | CNR1 | CNR1 StanfordSource, GeneCards | cannabinoid receptor 1 (brain) | 9496 | -0.233 | -0.0154 | No |
| 92 | VEGF | VEGF StanfordSource, GeneCards | vascular endothelial growth factor | 9617 | -0.251 | -0.0112 | No |
| 93 | PPP3CB | PPP3CB StanfordSource, GeneCards | protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) | 9639 | -0.254 | 0.0030 | No |
| 94 | RELA | RELA StanfordSource, GeneCards | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 9904 | -0.317 | -0.0030 | No |
| 95 | EP300 | EP300 StanfordSource, GeneCards | E1A binding protein p300 | 9993 | -0.349 | 0.0106 | No |
