Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | p53_full_useme_maxed_cs.gct |
| Phenotype | MUT |
| GeneSet | s2.symbols.gmt#pdgfPathway |
| Enrichment Score (ES) | -0.45095885 |
| Normalized Enrichment Score (NES) | -1.5190197 |
| Nominal p-value | 0.038793102 |
| FDR q-value | 0.5189599 |
| FWER p-Value | 0.956 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | STAT1 | STAT1 StanfordSource, GeneCards | signal transducer and activator of transcription 1, 91kDa | 2296 | 0.157 | -0.1798 | No |
| 2 | PDGFA | PDGFA StanfordSource, GeneCards | platelet-derived growth factor alpha polypeptide | 2795 | 0.131 | -0.1891 | No |
| 3 | MAPK3 | MAPK3 StanfordSource, GeneCards | mitogen-activated protein kinase 3 | 2905 | 0.125 | -0.1616 | No |
| 4 | STAT5A | STAT5A StanfordSource, GeneCards | signal transducer and activator of transcription 5A | 3259 | 0.109 | -0.1634 | No |
| 5 | PLCG1 | PLCG1 StanfordSource, GeneCards | phospholipase C, gamma 1 (formerly subtype 148) | 3357 | 0.105 | -0.1409 | No |
| 6 | PIK3R1 | PIK3R1 StanfordSource, GeneCards | phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 3882 | 0.080 | -0.1685 | No |
| 7 | GRB2 | GRB2 StanfordSource, GeneCards | growth factor receptor-bound protein 2 | 4102 | 0.070 | -0.1689 | No |
| 8 | MAP2K4 | MAP2K4 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 4 | 4310 | 0.060 | -0.1709 | No |
| 9 | PRKCA | PRKCA StanfordSource, GeneCards | protein kinase C, alpha | 5086 | 0.027 | -0.2397 | No |
| 10 | JUN | JUN StanfordSource, GeneCards | v-jun sarcoma virus 17 oncogene homolog (avian) | 5283 | 0.019 | -0.2532 | No |
| 11 | JAK1 | JAK1 StanfordSource, GeneCards | Janus kinase 1 (a protein tyrosine kinase) | 5657 | 0.002 | -0.2895 | No |
| 12 | PRKCB1 | PRKCB1 StanfordSource, GeneCards | protein kinase C, beta 1 | 6340 | -0.029 | -0.3483 | No |
| 13 | SHC1 | SHC1 StanfordSource, GeneCards | SHC (Src homology 2 domain containing) transforming protein 1 | 6401 | -0.032 | -0.3444 | No |
| 14 | PDGFRA | PDGFRA StanfordSource, GeneCards | platelet-derived growth factor receptor, alpha polypeptide | 7475 | -0.086 | -0.4245 | Yes |
| 15 | RASA1 | RASA1 StanfordSource, GeneCards | RAS p21 protein activator (GTPase activating protein) 1 | 7533 | -0.089 | -0.4030 | Yes |
| 16 | HRAS | HRAS StanfordSource, GeneCards | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 7563 | -0.090 | -0.3781 | Yes |
| 17 | STAT3 | STAT3 StanfordSource, GeneCards | signal transducer and activator of transcription 3 (acute-phase response factor) | 7827 | -0.105 | -0.3720 | Yes |
| 18 | SRF | SRF StanfordSource, GeneCards | serum response factor (c-fos serum response element-binding transcription factor) | 7906 | -0.109 | -0.3463 | Yes |
| 19 | MAPK8 | MAPK8 StanfordSource, GeneCards | mitogen-activated protein kinase 8 | 7956 | -0.112 | -0.3168 | Yes |
| 20 | SOS1 | SOS1 StanfordSource, GeneCards | son of sevenless homolog 1 (Drosophila) | 8043 | -0.116 | -0.2898 | Yes |
| 21 | CSNK2A1 | CSNK2A1 StanfordSource, GeneCards | casein kinase 2, alpha 1 polypeptide | 8167 | -0.125 | -0.2636 | Yes |
| 22 | FOS | FOS StanfordSource, GeneCards | v-fos FBJ murine osteosarcoma viral oncogene homolog | 8716 | -0.163 | -0.2681 | Yes |
| 23 | RAF1 | RAF1 StanfordSource, GeneCards | v-raf-1 murine leukemia viral oncogene homolog 1 | 8728 | -0.164 | -0.2190 | Yes |
| 24 | MAP3K1 | MAP3K1 StanfordSource, GeneCards | mitogen-activated protein kinase kinase kinase 1 | 8906 | -0.177 | -0.1824 | Yes |
| 25 | ELK1 | ELK1 StanfordSource, GeneCards | ELK1, member of ETS oncogene family | 9250 | -0.205 | -0.1537 | Yes |
| 26 | PIK3CA | PIK3CA StanfordSource, GeneCards | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 10023 | -0.366 | -0.1181 | Yes |
| 27 | MAP2K1 | MAP2K1 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 1 | 10067 | -0.410 | 0.0032 | Yes |
