Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | p53_full_useme_maxed_cs.gct |
| Phenotype | MUT |
| GeneSet | s2.symbols.gmt#proteasomePathway |
| Enrichment Score (ES) | -0.5456378 |
| Normalized Enrichment Score (NES) | -1.4237051 |
| Nominal p-value | 0.12456141 |
| FDR q-value | 0.677416 |
| FWER p-Value | 0.994 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PSMB4 | PSMB4 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, beta type, 4 | 1418 | 0.212 | -0.0634 | No |
| 2 | PSMA7 | PSMA7 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, alpha type, 7 | 2945 | 0.124 | -0.1697 | No |
| 3 | PSMB6 | PSMB6 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, beta type, 6 | 3916 | 0.078 | -0.2376 | No |
| 4 | RPN1 | RPN1 StanfordSource, GeneCards | ribophorin I | 5047 | 0.028 | -0.3394 | No |
| 5 | PSMB3 | PSMB3 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, beta type, 3 | 5356 | 0.016 | -0.3640 | No |
| 6 | UBE3A | UBE3A StanfordSource, GeneCards | ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) | 5621 | 0.004 | -0.3888 | No |
| 7 | UBE2A | UBE2A StanfordSource, GeneCards | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 5851 | -0.006 | -0.4093 | No |
| 8 | PSMA3 | PSMA3 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, alpha type, 3 | 6520 | -0.038 | -0.4620 | No |
| 9 | PSMA1 | PSMA1 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, alpha type, 1 | 7264 | -0.074 | -0.5086 | No |
| 10 | PSMB5 | PSMB5 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, beta type, 5 | 7638 | -0.094 | -0.5113 | Yes |
| 11 | PSMA6 | PSMA6 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, alpha type, 6 | 7762 | -0.102 | -0.4865 | Yes |
| 12 | PSMD14 | PSMD14 StanfordSource, GeneCards | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 7964 | -0.112 | -0.4656 | Yes |
| 13 | RPN2 | RPN2 StanfordSource, GeneCards | ribophorin II | 8383 | -0.140 | -0.4560 | Yes |
| 14 | UBE1 | UBE1 StanfordSource, GeneCards | ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) | 8643 | -0.159 | -0.4239 | Yes |
| 15 | PSMB2 | PSMB2 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, beta type, 2 | 8694 | -0.162 | -0.3700 | Yes |
| 16 | PSMA4 | PSMA4 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, alpha type, 4 | 8817 | -0.171 | -0.3200 | Yes |
| 17 | PSMB7 | PSMB7 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, beta type, 7 | 9104 | -0.193 | -0.2784 | Yes |
| 18 | PSMA2 | PSMA2 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, alpha type, 2 | 9303 | -0.210 | -0.2216 | Yes |
| 19 | PSMA5 | PSMA5 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, alpha type, 5 | 9656 | -0.257 | -0.1629 | Yes |
| 20 | PSMC3 | PSMC3 StanfordSource, GeneCards | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 9680 | -0.260 | -0.0704 | Yes |
| 21 | PSMB1 | PSMB1 StanfordSource, GeneCards | proteasome (prosome, macropain) subunit, beta type, 1 | 9877 | -0.308 | 0.0220 | Yes |
