Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | p53_full_useme_maxed_cs.gct |
| Phenotype | MUT |
| GeneSet | s2.symbols.gmt#rasPathway |
| Enrichment Score (ES) | -0.6030778 |
| Normalized Enrichment Score (NES) | -1.8941661 |
| Nominal p-value | 0.0017605633 |
| FDR q-value | 0.28430656 |
| FWER p-Value | 0.176 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAPK3 | MAPK3 StanfordSource, GeneCards | mitogen-activated protein kinase 3 | 2905 | 0.125 | -0.2524 | No |
| 2 | AKT1 | AKT1 StanfordSource, GeneCards | v-akt murine thymoma viral oncogene homolog 1 | 3184 | 0.112 | -0.2479 | No |
| 3 | PIK3R1 | PIK3R1 StanfordSource, GeneCards | phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 3882 | 0.080 | -0.2943 | No |
| 4 | RALGDS | RALGDS StanfordSource, GeneCards | ral guanine nucleotide dissociation stimulator | 4232 | 0.064 | -0.3107 | No |
| 5 | CHUK | CHUK StanfordSource, GeneCards | conserved helix-loop-helix ubiquitous kinase | 4288 | 0.062 | -0.2985 | No |
| 6 | NFKB1 | NFKB1 StanfordSource, GeneCards | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 5616 | 0.004 | -0.4290 | No |
| 7 | BCL2L1 | BCL2L1 StanfordSource, GeneCards | BCL2-like 1 | 7371 | -0.080 | -0.5801 | Yes |
| 8 | RALA | RALA StanfordSource, GeneCards | v-ral simian leukemia viral oncogene homolog A (ras related) | 7447 | -0.084 | -0.5635 | Yes |
| 9 | HRAS | HRAS StanfordSource, GeneCards | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 7563 | -0.090 | -0.5491 | Yes |
| 10 | CDC42 | CDC42 StanfordSource, GeneCards | cell division cycle 42 (GTP binding protein, 25kDa) | 7665 | -0.096 | -0.5316 | Yes |
| 11 | BAD | BAD StanfordSource, GeneCards | BCL2-antagonist of cell death | 7728 | -0.099 | -0.5093 | Yes |
| 12 | RALBP1 | RALBP1 StanfordSource, GeneCards | ralA binding protein 1 | 8515 | -0.150 | -0.5445 | Yes |
| 13 | CASP9 | CASP9 StanfordSource, GeneCards | caspase 9, apoptosis-related cysteine protease | 8578 | -0.154 | -0.5067 | Yes |
| 14 | RAF1 | RAF1 StanfordSource, GeneCards | v-raf-1 murine leukemia viral oncogene homolog 1 | 8728 | -0.164 | -0.4747 | Yes |
| 15 | RHOA | RHOA StanfordSource, GeneCards | ras homolog gene family, member A | 9025 | -0.187 | -0.4506 | Yes |
| 16 | MLLT7 | MLLT7 StanfordSource, GeneCards | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7 | 9047 | -0.188 | -0.3990 | Yes |
| 17 | H2AFX | H2AFX StanfordSource, GeneCards | H2A histone family, member X | 9226 | -0.203 | -0.3586 | Yes |
| 18 | ELK1 | ELK1 StanfordSource, GeneCards | ELK1, member of ETS oncogene family | 9250 | -0.205 | -0.3023 | Yes |
| 19 | RAC1 | RAC1 StanfordSource, GeneCards | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 9657 | -0.258 | -0.2689 | Yes |
| 20 | RELA | RELA StanfordSource, GeneCards | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 9904 | -0.317 | -0.2027 | Yes |
| 21 | PIK3CA | PIK3CA StanfordSource, GeneCards | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 10023 | -0.366 | -0.1097 | Yes |
| 22 | MAP2K1 | MAP2K1 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 1 | 10067 | -0.410 | 0.0032 | Yes |
