Gene Set: ANDERSEN_LIVER_CANCER_KRT19_UP

Standard name ANDERSEN_LIVER_CANCER_KRT19_UP
Systematic name M416
Brief description Genes over-expressed in KRT19-positive [GeneID=3880] hepatocellular carcinoma.
Full description or abstract In approximately 70% of patients with hepatocellular carcinoma (HCC) treated by resection or ablation, disease recurs within 5 years. Although gene expression signatures have been associated with outcome, there is no method to predict recurrence based on combined clinical, pathology, and genomic data (from tumor and cirrhotic tissue). We evaluated gene expression signatures associated with outcome in a large cohort of patients with early stage (Barcelona-Clinic Liver Cancer 0/A), single-nodule HCC and heterogeneity of signatures within tumor tissues.
Collection C2: curated gene sets
      CGP: chemical and genetic perturbations
Source publication Pubmed 21320499   Authors: Villanueva A,Hoshida Y,Battiston C,Tovar V,Sia D,Alsinet C,Cornella H,Liberzon A,Kobayashi M,Kumada H,Thung SN,Bruix J,Newell P,April C,Fan JB,Roayaie S,Mazzaferro V,Schwartz ME,Llovet JM
Exact source Table S3: Fold-change > 1
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(show 25 gene sets from the same authors)
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Organism Homo sapiens
Contributed by Yujin Hoshida (Broad Institute)
Source platform Human_NCBI_Gene_ID
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Version history 6.2: First introduced

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