Overview
The Molecular Signatures Database (MSigDB) is a collection of annotated gene sets for use with GSEA software. From this
web site, you can
- Search for gene sets by keyword.
- Browse gene sets by name or collection.
- Examine a gene set and
its annotations. See, for example, the
HALLMARK_APOPTOSIS gene set page.
- Download gene sets.
- Investigate gene sets:
- Compute overlaps between your gene set and gene sets in MSigDB.
- Categorize members of a gene set by gene families.
- View the expression profile of a gene set in a provided public expression compendia.
- Investigate the gene set in the online biological network repository NDEx
License Terms
GSEA and MSigDB are available for use under these license terms.
Please register to download the GSEA software and the MSigDB gene sets,
and to use our web tools. After registering, you can log in at any time using your email address. Registration is free.
Its only purpose is to help us track usage for reports to our funding agencies.
Current Version
MSigDB database v7.5.1 updated January 2022.
Release notes.
Citing the MSigDB
To cite your use of the Molecular Signatures Database (MSigDB), a joint project of UC San Diego and Broad Institute,
please reference Subramanian, Tamayo, et al.
(2005, PNAS) and
one or more of the following as appropriate:
Liberzon, et al. (2011, Bioinformatics),
Liberzon, et al. (2015, Cell Systems),
and also the source for the gene set as listed on the gene set page.
Funding
GSEA and MSigDB are currently funded by a grant from NCI's
Informatics Technology for Cancer Research (ITCR)
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