Human Gene Set: DANG_REGULATED_BY_MYC_UP


Standard name DANG_REGULATED_BY_MYC_UP
Systematic name M18501
Brief description Genes up-regulated by MYC [GeneID=4609], according to the MYC Target Gene Database.
Full description or abstract We report a database of genes responsive to the Myc oncogenic transcription factor. The database Myc Target Gene prioritizes candidate target genes according to experimental evidence and clusters responsive genes into functional groups. We coupled the prioritization of target genes with phylogenetic sequence comparisons to predict c-Myc target binding sites, which are in turn validated by chromatin immunoprecipitation assays. This database is essential for the understanding of the genetic regulatory networks underlying the genesis of cancers.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 14519204   Authors: Zeller KI,Jegga AG,Aronow BJ,O'Donnell KA,Dang CV
Exact source http://www.myccancergene.org/site/mycTargetDB.asp
Related gene sets (show 4 additional gene sets from the source publication)

(show 15 gene sets from any of these authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Chi Dang (Johns Hopkins University)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 68 genes
Gene families ? Categorize these 68 genes by gene family
Show members (show 72 source identifiers mapped to 68 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.