Human Gene Set: EIF4E_UP


Standard name EIF4E_UP
Systematic name M2791
Brief description Genes up-regulated in HMEC cells (primary mammary epithelium) upon over-expression of EIF4E [GeneID=1977] gene.
Full description or abstract Translation initiation factor 4E confers primary human cells with neoplastic properties. A comparison of HMEC/hTERT and HMEC/hTERT/eIF4E cells using both total and polyribosoaml associated RNA.
Collection C6: Oncogenic Signature
Source publication Pubmed 17638893   Authors: Larsson O,Li S,Issaenko OA,Avdulov S,Peterson M,Smith K,Bitterman PB,Polunovsky VA
Exact source overexpression of eIFGI vs control; top 100 genes (diff. of means)
Related gene sets (show 1 additional gene sets from the source publication)

(show 135 gene sets from any of these authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 100 genes
Gene families ? Categorize these 100 genes by gene family
Show members (show 100 source identifiers mapped to 100 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.