Gene Set: FAN_OVARY_CL16_LYMPHATIC_ENDOTHELIAL_CELL

Standard name FAN_OVARY_CL16_LYMPHATIC_ENDOTHELIAL_CELL
Systematic name M41718
Brief description We identified three separate clusters (CL) of endothelial cells (CL7, CL9, CL16) expressing markers associated with lymph and blood vascular system (such as PECAM1, CD34, CTGF), but also associated with remodeling and inflammatory response (such as TXNIP, ANGPT2) (Fig. 3a-d). The DEGs of CL7 (such as CCL14, SOCS3, EGFL7) and CL16 (such as CCL21, TFF3) are linked to angiogenesis and lymphatics, respectively, while DEGs of CL9 (TM4SF1, NMMT) were more related to regulation of apoptosis (Fig. 3c, d).
Full description or abstract  
Collection C8: cell type signature gene sets
Source publication Pubmed 31320652   Authors: Fan X,Bialecka M,Moustakas I,Lam E,Torrens-Juaneda V,Borggreven NV,Trouw L,Louwe LA,Pilgram GSK,Mei H,van der Westerlaken L,Chuva de Sousa Lopes SM
Exact source Supplementary Data 2 (complete underlying data received from authors), avg_logFC > 0.25, p_val_adj <0.05
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External links https://doi.org/10.1038/s41467-019-11036-9
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Organism Homo sapiens
Contributed by Anthony Castanza (MSigDB Team)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: First Introduced.

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