Gene Set: GSE12839_CTRL_VS_IL12_TREATED_PBMC_DN

Standard name GSE12839_CTRL_VS_IL12_TREATED_PBMC_DN
Systematic name M441
Brief description Genes down-regulated in peripheral blood monocytes (PBMC): control versus IL-12 stimulation.
Full description or abstract The cytokine interleukin-12 (IL-12) is known to play a central role in adaptive and innate immunity. We employed microarray analysis of IL-12 induced gene expression to provide further insights into its effects on immune response.
Collection C7: immunologic signature gene sets
      IMMUNESIGDB: ImmuneSigDB gene sets
Source publication Pubmed 19001140   Authors: Watford WT,Hissong BD,Durant LR,Yamane H,Muul LM,Kanno Y,Tato CM,Ramos HL,Berger AE,Mielke L,Pesu M,Solomon B,Frucht DM,Paul WE,Sher A,Jankovic D,Tsichlis PN,O'Shea JJ
Exact source GSE12839_2401_200_DN
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Organism Homo sapiens
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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