Gene Set: GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_DN

Standard name GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_DN
Systematic name M8106
Brief description Genes down-regulated in IL10 [GeneID=3586] knockout macrophages: unstimulated versus LPS.
Full description or abstract Bone marrow-derived macrophages were produced from mice lacking IL-10 alone (IL10-def) or mice lacking both IL-10 and the p50/p105 subunit of NF-kB (p50/IL10), and left unstimulated, stimulated with LPS (1 ng/ml) or stimulated with LPS and IL-10 (0.3 ng/ml).
Collection C7: immunologic signature gene sets
      IMMUNESIGDB: ImmuneSigDB gene sets
Source publication Pubmed 21217011   Authors: Yang HT,Wang Y,Zhao X,Demissie E,Papoutsopoulou S,Mambole A,O'Garra A,Tomczak MF,Erdman SE,Fox JG,Ley SC,Horwitz BH
Exact source GSE19941_3666_200_DN
Related gene sets (show 17 additional gene sets from the source publication)

(show 64 gene sets from the same authors)
External links  
Filtered by similarity
Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | text | gmt | gmx | xml
Compute overlaps (show collections to investigate for overlap with this gene set)
Compendia expression profiles GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 200 genes
Gene families Categorize these 200 genes by gene family
Show members (show 200 members mapped to 200 genes)
Version history 7.3: Moved to ImmuneSigDB sub-collection.

See MSigDB license terms here. Please note that certain gene sets have special access terms.