Gene Set: GSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_DN

Standard name GSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_DN
Systematic name M9385
Brief description Genes down-regulated in follicular B lymphocytes with BCL6 [GeneID=604] knockout: heterozygotic versus homozygotic strains.
Full description or abstract Bcl6 germline deletion causes a prominent inflammatory disease, owing to over-expression of Th2 cytokines, and affects the properties of B cells prior to immunization. Therefore we established the B cell-specific Bcl6 deletion mice and analyze the gene expression of naive B cells under physiological conditions.
Collection C7: immunologic signature gene sets
      IMMUNESIGDB: ImmuneSigDB gene sets
Source publication Pubmed 23027924   Authors: Kaji T,Ishige A,Hikida M,Taka J,Hijikata A,Kubo M,Nagashima T,Takahashi Y,Kurosaki T,Okada M,Ohara O,Rajewsky K,Takemori T
Exact source GSE28737_2489_200_DN
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(show 64 gene sets from the same authors)
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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