Human Gene Set: GSE29614_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_DN
Standard name
GSE29614_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_DN
Systematic name
M4907
Brief description
Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those from day 3 post-vaccination.
Full description or abstract
Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling applied to vaccinology. Here we used the systems vaccinology approach to study the molecular mechanisms underlying the innate responses to the trivalent inactivated influenza (TIV) and live attenuated influenza (LAIV) vaccination in humans, and to identify early gene signatures that predict the magnitude of the antibody responses to influenza vaccination.
We need your help: Update on GSEA/MSigDB funding support
Last November we submitted a proposal to NCI's Information Technology for Cancer Research (ITCR) program for the continued
funding of GSEA and MSigDB. Unfortunately, our proposal was not funded in this round, but we were encouraged to resubmit
for the next one. This funding is critical for our continuing support and enhancement of the GSEA-MSigDB resource.
For our original submission many of you sent us emails of support, an important requirement for these grants. We
now ask for your help again. We would greatly appreciate a short email message from you describing how the resource
has been of value to your work and any concerns you may have about its continued availability.
