Gene Set: GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_UP

Standard name GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_UP
Systematic name M8396
Brief description Genes up-regulated in brain microglia versus spleen CD8+ dendritic cells.
Full description or abstract To understand the functional relationship between brain dendritic cells (brain DCs) and other myeloid cells, we compared the gene expression profile of m/chDCs to that of bone marrow monocytes, brain microglia and classical spleen CD8+ and CD8- DCs. In order to obtain enough brain DCs for mRNA extraction, we expanded brain DCs with in vivo Flt3L treatment before purification.
Collection C7: immunologic signature gene sets
      IMMUNESIGDB: ImmuneSigDB gene sets
Source publication Pubmed 21788405   Authors: Anandasabapathy N,Victora GD,Meredith M,Feder R,Dong B,Kluger C,Yao K,Dustin ML,Nussenzweig MC,Steinman RM,Liu K
Exact source GSE29949_3445_200_UP
Related gene sets (show 19 additional gene sets from the source publication)

(show 73 gene sets from the same authors)
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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