Gene Set: GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_DN

Standard name GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_DN
Systematic name M8389
Brief description Genes down-regulated in brain microglia versus bone marrow monocytes.
Full description or abstract To understand the functional relationship between brain dendritic cells (brain DCs) and other myeloid cells, we compared the gene expression profile of m/chDCs to that of bone marrow monocytes, brain microglia and classical spleen CD8+ and CD8- DCs. In order to obtain enough brain DCs for mRNA extraction, we expanded brain DCs with in vivo Flt3L treatment before purification.
Collection C7: immunologic signature gene sets
      IMMUNESIGDB: ImmuneSigDB gene sets
Source publication Pubmed 21788405   Authors: Anandasabapathy N,Victora GD,Meredith M,Feder R,Dong B,Kluger C,Yao K,Dustin ML,Nussenzweig MC,Steinman RM,Liu K
Exact source GSE29949_3447_200_DN
Related gene sets (show 19 additional gene sets from the source publication)

(show 73 gene sets from the same authors)
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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