Standard name GSE31622_WT_VS_KLF3_KO_BCELL_DN
Systematic name M8471
Brief description Genes down-regulated in splenic B lymphocytes: wildtype versus KLF3 [GeneID=51274] knockout.
Full description or abstract To investigate the roles of Klf3 in B lymphopoiesis, CD19+ B cells were sorted from the spleens of WT and Klf3 KO mice (Molecular and Cellular Biology (2008); 28:3967?3978). Following RNA extraction, gene expression was compared in WT and Klf3 KO CD19+splenic B cells using Affymetrix microarrays.
Collection C7: immunologic signature gene sets
      IMMUNESIGDB: ImmuneSigDB gene sets
Source publication Pubmed 22003205   Authors: Vu TT,Gatto D,Turner V,Funnell AP,Mak KS,Norton LJ,Kaplan W,Cowley MJ,Agenès F,Kirberg J,Brink R,Pearson RC,Crossley M
Exact source GSE31622_2717_200_DN
Related gene sets (show 1 additional gene sets from the source publication)

(show 44 gene sets from the same authors)
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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