Systematic name M9543
Brief description Genes down-regulated in macrophages: resting versus stimulated by IL4 [GeneID=3565].
Full description or abstract Analysis of alternative activation of macrophages at gene expression level. The study forms part of a wider study where we compare the effects of IL-4 in different human and mouse macrophages. Our results support the notion that in vitro culture conditions greatly affect the macrophage response to IL-4. Total RNA obtained from bone marrow derived macrophages upon exposure to 20 ng/ml of IL-4 for 18 hours.
Collection C7: immunologic signature gene sets
      IMMUNESIGDB: ImmuneSigDB gene sets
Source publication Pubmed 23293084   Authors: Martinez FO,Helming L,Milde R,Varin A,Melgert BN,Draijer C,Thomas B,Fabbri M,Crawshaw A,Ho LP,Hacken Ten NH,Jiménez Cobos V,Kootstra NA,Hamann J,Greaves DR,Locati M,Mantovani A,Gordon S
Exact source GSE35435_3809_200_DN
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(show 28 gene sets from the same authors)
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Compendia expression profiles GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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