Human Gene Set: GSE37532_WT_VS_PPARG_KO_LN_TREG_DN


Standard name GSE37532_WT_VS_PPARG_KO_LN_TREG_DN
Systematic name M8953
Brief description Genes down-regulated in T reg from lypmh nodes of elderly (retired breeder) mice: wildtype versus PPARG [GeneID=5468] knockout.
Full description or abstract We identified Pparg as a major orchestrator of the phenotype of adipose-tissue resident regulatory T cells (VAT Tregs). To establish the role of Pparg in shaping the VAT Tregs gene profile and cell dynamics, Tregs from lymph nodes and visceral adipose tissue of mice sufficient and deficient of Pparg expression in Tregs were double sorted for microarray analysis.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 22722857   Authors: Cipolletta D,Feuerer M,Li A,Kamei N,Lee J,Shoelson SE,Benoist C,Mathis D
Exact source GSE37532_2853_200_DN
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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