Gene Set: GSE4811_CLASSSICALY_ACTIVATED_VS_TYPE_2_ACTIVATED_MACROPHAGE_DN

Standard name GSE4811_CLASSSICALY_ACTIVATED_VS_TYPE_2_ACTIVATED_MACROPHAGE_DN
Systematic name M6548
Brief description Genes down-regulated in activated macrophages: classically (M1) versus alternative (M2).
Full description or abstract The purpose of this study is to identify novel markers for the type II activated macrophage, which is generated by classical stimulation in the presence if IgG immune complexes. These cells gererally produce high levels of IL-10 and low levels of IL-12, in comparison to classically activated macrophages. We wish to identify gene expression which is enriched in Type II activated macrophages in comparison to classically activated macrophages.
Collection C7: immunologic signatures
Source publication Pubmed 16905575   Authors: Edwards JP,Zhang X,Frauwirth KA,Mosser DM
Exact source GSE4811_3341_200_DN
Related gene sets (show 1 additional gene sets from the source publication)

(show 372 gene sets from the same authors)
External links  
Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | text | gmt | gmx | xml
Compute overlaps (show collections to investigate for overlap with this gene set)
Compendia expression profiles GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 200 genes
Gene families Categorize these 200 genes by gene family
Show members (show 200 members mapped to 200 genes)
Version history 5.1: First introduced

See MSigDB license terms here. Please note that certain gene sets have special access terms.