Human Gene Set: MINGUEZ_LIVER_CANCER_VASCULAR_INVASION_DN


Standard name MINGUEZ_LIVER_CANCER_VASCULAR_INVASION_DN
Systematic name M398
Brief description Genes under-expressed in hepatocellular carcinoma (HCC) with vascular invasion.
Full description or abstract In approximately 70% of patients with hepatocellular carcinoma (HCC) treated by resection or ablation, disease recurs within 5 years. Although gene expression signatures have been associated with outcome, there is no method to predict recurrence based on combined clinical, pathology, and genomic data (from tumor and cirrhotic tissue). We evaluated gene expression signatures associated with outcome in a large cohort of patients with early stage (Barcelona-Clinic Liver Cancer 0/A), single-nodule HCC and heterogeneity of signatures within tumor tissues.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 21320499   Authors: Villanueva A,Hoshida Y,Battiston C,Tovar V,Sia D,Alsinet C,Cornella H,Liberzon A,Kobayashi M,Kumada H,Thung SN,Bruix J,Newell P,April C,Fan JB,Roayaie S,Mazzaferro V,Schwartz ME,Llovet JM
Exact source Table 2: Signal-to-noise ratio < 0
Related gene sets (show 11 additional gene sets from the source publication)

(show 82 gene sets from any of these authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Yujin Hoshida (Broad Institute)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 21 genes
Gene families ? Categorize these 21 genes by gene family
Show members (show 21 source identifiers mapped to 21 genes)
Version history 6.2: First introduced

See MSigDB license terms here. Please note that certain gene sets have special access terms.