Browse Gene Sets

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[about the MSigDB collections]

  • H (hallmark gene sets, 50 gene sets)
  • C1 (positional gene sets, 278 gene sets)
  • C2 (curated gene sets, 6290 gene sets)
    • CGP (chemical and genetic perturbations, 3368 gene sets)
    • CP (canonical pathways, 2922 gene sets)
  • C3 (regulatory target gene sets, 3731 gene sets)
    • MIR (microRNA targets, 2598 gene sets)
    • TFT (all transcription factor targets, 1133 gene sets)
      • TFT:GTRD (GTRD transcription factor targets, 523 gene sets)
      • TFT:TFT_Legacy (legacy transcription factor targets, 610 gene sets)
  • C4 (computational gene sets, 858 gene sets)
    • CGN (cancer gene neighborhoods, 427 gene sets)
    • CM (cancer modules, 431 gene sets)
  • C5 (ontology gene sets, 14998 gene sets)
    • GO (Gene Ontology, 10185 gene sets)
      • GO:BP (GO biological process, 7481 gene sets)
      • GO:CC (GO cellular component, 996 gene sets)
      • GO:MF (GO molecular function, 1708 gene sets)
    • HPO (Human Phenotye Ontology, 4813 gene sets)
  • C6 (oncogenic signature gene sets, 189 gene sets)
  • C7 (immunologic signature gene sets, 5219 gene sets)
    • IMMUNESIGDB (ImmuneSigDB gene sets, 4872 gene sets)
    • VAX (vaccine response gene sets, 347 gene sets)
  • C8 (cell type signature gene sets, 671 gene sets)

Gene sets starting with L

Click on a gene set name to view its gene set page.

LA_MEN1_TARGETS
LAIHO_COLORECTAL_CANCER_SERRATED_DN
LAIHO_COLORECTAL_CANCER_SERRATED_UP
LAKE_ADULT_KIDNEY_C10_THIN_ASCENDIN
G_LIMB

LAKE_ADULT_KIDNEY_C11_THIN_ASCENDIN
G_LIMB

LAKE_ADULT_KIDNEY_C12_THICK_ASCENDI
NG_LIMB

LAKE_ADULT_KIDNEY_C13_THICK_ASCENDI
NG_LIMB

LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOL
UTED_TUBULE

LAKE_ADULT_KIDNEY_C15_CONNECTING_TU
BULE

LAKE_ADULT_KIDNEY_C16_COLLECTING_SY
STEM_PRINCIPAL_CELLS_CORTEX

LAKE_ADULT_KIDNEY_C17_COLLECTING_SY
STEM_PCS_STRESSED_DISSOC_SUBSET

LAKE_ADULT_KIDNEY_C18_COLLECTING_DU
CT_PRINCIPAL_CELLS_MEDULLA

LAKE_ADULT_KIDNEY_C19_COLLECTING_DU
CT_INTERCALATED_CELLS_TYPE_A_MEDULL
A

LAKE_ADULT_KIDNEY_C1_EPITHELIAL_CEL
LS_UNASSIGNED

LAKE_ADULT_KIDNEY_C20_COLLECTING_DU
CT_INTERCALATED_CELLS_TYPE_A_CORTEX

LAKE_ADULT_KIDNEY_C21_COLLECTING_DU
CT_INTERCALATED_CELLS_TYPE_B

LAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_C
ELLS_GLOMERULAR_CAPILLARIES

LAKE_ADULT_KIDNEY_C23_ENDOTHELIAL_C
ELLS_AVR

LAKE_ADULT_KIDNEY_C24_ENDOTHELIAL_C
ELLS_AEA_AND_DVR

LAKE_ADULT_KIDNEY_C25_ENDOTHELIAL_C
ELLS_UNASSIGNED

LAKE_ADULT_KIDNEY_C26_MESANGIAL_CEL
LS

LAKE_ADULT_KIDNEY_C27_VASCULAR_SMOO
TH_MUSCLE_CELLS_AND_PERICYTES

LAKE_ADULT_KIDNEY_C28_INTERSTITIUM
LAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL
_PT_CFH_POS_SUBPOPULATION_S2

LAKE_ADULT_KIDNEY_C2_PODOCYTES
LAKE_ADULT_KIDNEY_C30_IMMUNE_CELLS_
MACROPHAGES

LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBUL
E_EPITHELIAL_CELLS_S1_S2

LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBUL
E_EPITHELIAL_CELLS_S2

LAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBUL
E_EPITHELIAL_CELLS_STRESS_INFLAM

LAKE_ADULT_KIDNEY_C6_PROXIMAL_TUBUL
E_EPITHELIAL_CELLS_FIBRINOGEN_POS_S
3

LAKE_ADULT_KIDNEY_C7_PROXIMAL_TUBUL
E_EPITHELIAL_CELLS_S3

LAKE_ADULT_KIDNEY_C8_DECENDING_THIN
_LIMB

LAKE_ADULT_KIDNEY_C9_THIN_ASCENDING
_LIMB

LAMB3_TARGET_GENES
LAMB_CCND1_TARGETS
LAMTOR5_TARGET_GENES
LANDEMAINE_LUNG_METASTASIS
LANDIS_BREAST_CANCER_PROGRESSION_DN
LANDIS_BREAST_CANCER_PROGRESSION_UP
LANDIS_ERBB2_BREAST_PRENEOPLASTIC_D
N

LANDIS_ERBB2_BREAST_PRENEOPLASTIC_U
P

LANDIS_ERBB2_BREAST_TUMORS_324_DN
LANDIS_ERBB2_BREAST_TUMORS_324_UP
LANDIS_ERBB2_BREAST_TUMORS_65_DN
LANDIS_ERBB2_BREAST_TUMORS_65_UP
LANG_MYB_FAMILY_TARGETS
LASTOWSKA_COAMPLIFIED_WITH_MYCN
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER
_DN

LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER
_UP

LAU_APOPTOSIS_CDKN2A_DN
LAU_APOPTOSIS_CDKN2A_UP
LBP1_Q6
LCORL_TARGET_GENES
LE_EGR2_TARGETS_DN
LE_EGR2_TARGETS_UP
LE_NEURONAL_DIFFERENTIATION_DN
LE_NEURONAL_DIFFERENTIATION_UP
LE_SKI_TARGETS_DN
LE_SKI_TARGETS_UP
LEE_AGING_CEREBELLUM_DN
LEE_AGING_CEREBELLUM_UP
LEE_AGING_MUSCLE_DN
LEE_AGING_MUSCLE_UP
LEE_AGING_NEOCORTEX_DN
LEE_AGING_NEOCORTEX_UP
LEE_BMP2_TARGETS_DN
LEE_BMP2_TARGETS_UP
LEE_CALORIE_RESTRICTION_MUSCLE_DN
LEE_CALORIE_RESTRICTION_MUSCLE_UP
LEE_CALORIE_RESTRICTION_NEOCORTEX_D
N

LEE_CALORIE_RESTRICTION_NEOCORTEX_U
P

LEE_DIFFERENTIATING_T_LYMPHOCYTE
LEE_DOUBLE_POLAR_THYMOCYTE
LEE_EARLY_T_LYMPHOCYTE_DN
LEE_EARLY_T_LYMPHOCYTE_UP
LEE_INTRATHYMIC_T_PROGENITOR
LEE_LIVER_CANCER
LEE_LIVER_CANCER_ACOX1_DN
LEE_LIVER_CANCER_ACOX1_UP
LEE_LIVER_CANCER_CIPROFIBRATE_DN
LEE_LIVER_CANCER_CIPROFIBRATE_UP
LEE_LIVER_CANCER_DENA_DN
LEE_LIVER_CANCER_DENA_UP
LEE_LIVER_CANCER_E2F1_DN
LEE_LIVER_CANCER_E2F1_UP
LEE_LIVER_CANCER_HEPATOBLAST
LEE_LIVER_CANCER_MYC_DN
LEE_LIVER_CANCER_MYC_E2F1_DN
LEE_LIVER_CANCER_MYC_E2F1_UP
LEE_LIVER_CANCER_MYC_TGFA_DN
LEE_LIVER_CANCER_MYC_TGFA_UP
LEE_LIVER_CANCER_MYC_UP
LEE_LIVER_CANCER_SURVIVAL_DN
LEE_LIVER_CANCER_SURVIVAL_UP
LEE_METASTASIS_AND_ALTERNATIVE_SPLI
CING_DN

LEE_METASTASIS_AND_ALTERNATIVE_SPLI
CING_UP

LEE_METASTASIS_AND_RNA_PROCESSING_U
P

LEE_NAIVE_T_LYMPHOCYTE
LEE_NEURAL_CREST_STEM_CELL_DN
LEE_NEURAL_CREST_STEM_CELL_UP
LEE_RECENT_THYMIC_EMIGRANT
LEE_SP4_THYMOCYTE
LEE_TARGETS_OF_PTCH1_AND_SUFU_DN
LEE_TARGETS_OF_PTCH1_AND_SUFU_UP
LEF1_Q2
LEF1_Q6
LEF1_UP.V1_DN
LEF1_UP.V1_UP
LEI_HOXC8_TARGETS_DN
LEI_HOXC8_TARGETS_UP
LEI_MYB_TARGETS
LEIN_ASTROCYTE_MARKERS
LEIN_CEREBELLUM_MARKERS
LEIN_CHOROID_PLEXUS_MARKERS
LEIN_LOCALIZED_TO_DISTAL_AND_PROXIM
AL_DENDRITES

LEIN_LOCALIZED_TO_PROXIMAL_DENDRITE
S

LEIN_MEDULLA_MARKERS
LEIN_MIDBRAIN_MARKERS
LEIN_NEURON_MARKERS
LEIN_OLIGODENDROCYTE_MARKERS
LEIN_PONS_MARKERS
LENAOUR_DENDRITIC_CELL_MATURATION_D
N

LENAOUR_DENDRITIC_CELL_MATURATION_U
P

LEONARD_HYPOXIA
LET_7A_2_3P
LET_7A_3P
LET_7A_5P_LET_7C_5P_LET_7E_5P
LET_7B_3P
LET_7B_5P
LET_7C_3P
LET_7D_3P
LET_7D_5P
LET_7E_3P
LET_7F_1_3P
LET_7F_2_3P
LET_7F_5P
LET_7G_3P
LET_7G_5P
LET_7I_3P
LET_7I_5P
LEUKOCYTE_ACTIVATION
LFA1_Q6
LHX2_TARGET_GENES
LHX3_01
LHX3_TARGET_GENES
LHX9_TARGET_GENES
LI_ADIPOGENESIS_BY_ACTIVATED_PPARG
LI_AMPLIFIED_IN_LUNG_CANCER
LI_CISPLATIN_RESISTANCE_DN
LI_CISPLATIN_RESISTANCE_UP
LI_CYTIDINE_ANALOG_PATHWAY
LI_CYTIDINE_ANALOGS_CYCTOTOXICITY
LI_DCP2_BOUND_MRNA
LI_INDUCED_T_TO_NATURAL_KILLER_DN
LI_INDUCED_T_TO_NATURAL_KILLER_UP
LI_LUNG_CANCER
LI_PBMC_MENACTRA_AGE_18_45YO_7DY_UP
LI_PBMC_MENACTRA_AGE_18_45YO_ANTI_D
T_ANTIBODY_CORRELATION_PROFILE_3DY_
DN

LI_PBMC_MENACTRA_AGE_18_45YO_ANTI_D
T_ANTIBODY_CORRELATION_PROFILE_3DY_
UP

LI_PBMC_MENACTRA_AGE_18_45YO_ANTI_P
OLYSACCHARIDE_ANTIBODY_CORRELATION_
PROFILE_3DY_DN

LI_PBMC_MENACTRA_AGE_18_45YO_ANTI_P
OLYSACCHARIDE_ANTIBODY_CORRELATION_
PROFILE_3DY_UP

LI_PBMC_MENACTRA_AGE_18_45YO_CORREL
ATED_WITH_ANTI_DT_ANTIBODY_3DY_NEGA
TIVE

LI_PBMC_MENACTRA_AGE_18_45YO_CORREL
ATED_WITH_ANTI_DT_ANTIBODY_3DY_POSI
TIVE

LI_PBMC_MENACTRA_AGE_18_45YO_CORREL
ATED_WITH_ANTI_POLYSACCHARIDE_ANTIB
ODY_3DY_NEGATIVE

LI_PBMC_MENACTRA_AGE_18_45YO_CORREL
ATED_WITH_ANTI_POLYSACCHARIDE_ANTIB
ODY_3DY_POSITIVE

LI_PBMC_MENOMUNE_A_C_Y_W_135_AGE_18
_45YO_3DY_DN

LI_PBMC_MENOMUNE_A_C_Y_W_135_AGE_18
_45YO_3DY_UP

LI_PBMC_MENOMUNE_A_C_Y_W_135_AGE_18
_45YO_CORRELATED_WITH_ANTIBODY_RESP
ONSE_3DY_NEGATIVE

LI_PBMC_MENOMUNE_A_C_Y_W_135_AGE_18
_45YO_CORRELATED_WITH_ANTIBODY_RESP
ONSE_3DY_POSITIVE

LI_PBMC_ZOSTAVAX_AGE_25_40_AND_60_7
9YO_1DY_UP

LI_PBMC_ZOSTAVAX_AGE_25_40_AND_60_7
9YO_3DY_UP

LI_PROSTATE_CANCER_EPIGENETIC
LI_WILMS_TUMOR
LI_WILMS_TUMOR_ANAPLASTIC_DN
LI_WILMS_TUMOR_ANAPLASTIC_UP
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_UP
LIAN_LIPA_TARGETS_3M
LIAN_LIPA_TARGETS_6M
LIAN_NEUTROPHIL_GRANULE_CONSTITUENT
S

LIANG_HEMATOPOIESIS_STEM_CELL_NUMBE
R_LARGE_VS_TINY_DN

LIANG_HEMATOPOIESIS_STEM_CELL_NUMBE
R_LARGE_VS_TINY_UP

LIANG_HEMATOPOIESIS_STEM_CELL_NUMBE
R_QTL

LIANG_HEMATOPOIESIS_STEM_CELL_NUMBE
R_SMALL_VS_HUGE_DN

LIANG_HEMATOPOIESIS_STEM_CELL_NUMBE
R_SMALL_VS_HUGE_UP

LIANG_SILENCED_BY_METHYLATION_2
LIANG_SILENCED_BY_METHYLATION_DN
LIANG_SILENCED_BY_METHYLATION_UP
LIAO_HAVE_SOX4_BINDING_SITES
LIAO_METASTASIS
LIEN_BREAST_CARCINOMA_METAPLASTIC
LIEN_BREAST_CARCINOMA_METAPLASTIC_V
S_DUCTAL_DN

LIEN_BREAST_CARCINOMA_METAPLASTIC_V
S_DUCTAL_UP

LIM_MAMMARY_LUMINAL_MATURE_DN
LIM_MAMMARY_LUMINAL_MATURE_UP
LIM_MAMMARY_LUMINAL_PROGENITOR_DN
LIM_MAMMARY_LUMINAL_PROGENITOR_UP
LIM_MAMMARY_STEM_CELL_DN
LIM_MAMMARY_STEM_CELL_UP
LIN_APC_TARGETS
LIN_MELANOMA_COPY_NUMBER_DN
LIN_MELANOMA_COPY_NUMBER_UP
LIN_NPAS4_TARGETS_DN
LIN_NPAS4_TARGETS_UP
LIN_SILENCED_BY_TUMOR_MICROENVIRONM
ENT

LIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK
LINDGREN_BLADDER_CANCER_CLUSTER_1_D
N

LINDGREN_BLADDER_CANCER_CLUSTER_1_U
P

LINDGREN_BLADDER_CANCER_CLUSTER_2A_
DN

LINDGREN_BLADDER_CANCER_CLUSTER_2A_
UP

LINDGREN_BLADDER_CANCER_CLUSTER_2B
LINDGREN_BLADDER_CANCER_CLUSTER_3_D
N

LINDGREN_BLADDER_CANCER_CLUSTER_3_U
P

LINDGREN_BLADDER_CANCER_HIGH_RECURR
ENCE

LINDGREN_BLADDER_CANCER_WITH_LOH_IN
_CHR9Q

LINDSTEDT_DENDRITIC_CELL_MATURATION
_A

LINDSTEDT_DENDRITIC_CELL_MATURATION
_B

LINDSTEDT_DENDRITIC_CELL_MATURATION
_C

LINDSTEDT_DENDRITIC_CELL_MATURATION
_D

LINDVALL_IMMORTALIZED_BY_TERT_DN
LINDVALL_IMMORTALIZED_BY_TERT_UP
LINSLEY_MIR16_TARGETS
LIPID_RAFT
LIU_BREAST_CANCER
LIU_CDX2_TARGETS_DN
LIU_CDX2_TARGETS_UP
LIU_CMYB_TARGETS_DN
LIU_CMYB_TARGETS_UP
LIU_COMMON_CANCER_GENES
LIU_IL13_MEMORY_MODEL_DN
LIU_IL13_MEMORY_MODEL_UP
LIU_IL13_PRIMING_MODEL
LIU_LIVER_CANCER
LIU_NASOPHARYNGEAL_CARCINOMA
LIU_PROSTATE_CANCER_DN
LIU_PROSTATE_CANCER_UP
LIU_SMARCA4_TARGETS
LIU_SOX4_TARGETS_DN
LIU_SOX4_TARGETS_UP
LIU_TARGETS_OF_VMYB_VS_CMYB_DN
LIU_TARGETS_OF_VMYB_VS_CMYB_UP
LIU_TOPBP1_TARGETS
LIU_VAV3_PROSTATE_CARCINOGENESIS_DN
LIU_VAV3_PROSTATE_CARCINOGENESIS_UP
LIU_VMYB_TARGETS_UP
LMNB2_TARGET_GENES
LMO2COM_01
LMO2COM_02
LMTK3_TARGET_GENES
LMX1B_TARGET_GENES
LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER
LOPES_METHYLATED_IN_COLON_CANCER_DN
LOPES_METHYLATED_IN_COLON_CANCER_UP
LOPEZ_EPITHELIOID_MESOTHELIOMA
LOPEZ_MBD_TARGETS
LOPEZ_MBD_TARGETS_IMPRINTED_AND_X_L
INKED

LOPEZ_MESOTELIOMA_SURVIVAL_TIME_DN
LOPEZ_MESOTELIOMA_SURVIVAL_TIME_UP
LOPEZ_MESOTHELIOMA_SURVIVAL_DN
LOPEZ_MESOTHELIOMA_SURVIVAL_OVERALL
_DN

LOPEZ_MESOTHELIOMA_SURVIVAL_OVERALL
_UP

LOPEZ_MESOTHELIOMA_SURVIVAL_UP
LOPEZ_MESOTHELIOMA_SURVIVAL_WORST_V
S_BEST_DN

LOPEZ_MESOTHELIOMA_SURVIVAL_WORST_V
S_BEST_UP

LOPEZ_TRANSLATION_VIA_FN1_SIGNALING
LTE2_UP.V1_DN
LTE2_UP.V1_UP
LU_AGING_BRAIN_DN
LU_AGING_BRAIN_UP
LU_EZH2_TARGETS_DN
LU_EZH2_TARGETS_UP
LU_IL4_SIGNALING
LU_TUMOR_ANGIOGENESIS_UP
LU_TUMOR_ENDOTHELIAL_MARKERS_DN
LU_TUMOR_ENDOTHELIAL_MARKERS_UP
LU_TUMOR_VASCULATURE_DN
LU_TUMOR_VASCULATURE_UP
LUCAS_HNF4A_TARGETS_DN
LUCAS_HNF4A_TARGETS_UP
LUDWICZEK_TREATING_IRON_OVERLOAD
LUI_TARGETS_OF_PAX8_PPARG_FUSION
LUI_THYROID_CANCER_CLUSTER_1
LUI_THYROID_CANCER_CLUSTER_2
LUI_THYROID_CANCER_CLUSTER_3
LUI_THYROID_CANCER_CLUSTER_4
LUI_THYROID_CANCER_CLUSTER_5
LUI_THYROID_CANCER_PAX8_PPARG_DN
LUI_THYROID_CANCER_PAX8_PPARG_UP
LUND_SILENCED_BY_METHYLATION
LXR_DR4_Q3
LXR_Q3
LY_AGING_MIDDLE_DN
LY_AGING_MIDDLE_UP
LY_AGING_OLD_DN
LY_AGING_OLD_UP
LY_AGING_PREMATURE_DN
LYF1_01
LYSOSOMAL_MEMBRANE
LYSOSOME
LYSOSOME_ORGANIZATION_AND_BIOGENESI
S

LYTIC_VACUOLE