Browse Gene Sets

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[about the MSigDB collections]

  • H (hallmark gene sets, 50 gene sets)
  • C1 (positional gene sets, 278 gene sets)
  • C2 (curated gene sets, 6290 gene sets)
    • CGP (chemical and genetic perturbations, 3368 gene sets)
    • CP (canonical pathways, 2922 gene sets)
  • C3 (regulatory target gene sets, 3731 gene sets)
    • MIR (microRNA targets, 2598 gene sets)
    • TFT (all transcription factor targets, 1133 gene sets)
      • TFT:GTRD (GTRD transcription factor targets, 523 gene sets)
      • TFT:TFT_Legacy (legacy transcription factor targets, 610 gene sets)
  • C4 (computational gene sets, 858 gene sets)
    • CGN (cancer gene neighborhoods, 427 gene sets)
    • CM (cancer modules, 431 gene sets)
  • C5 (ontology gene sets, 14998 gene sets)
    • GO (Gene Ontology, 10185 gene sets)
      • GO:BP (GO biological process, 7481 gene sets)
      • GO:CC (GO cellular component, 996 gene sets)
      • GO:MF (GO molecular function, 1708 gene sets)
    • HPO (Human Phenotye Ontology, 4813 gene sets)
  • C6 (oncogenic signature gene sets, 189 gene sets)
  • C7 (immunologic signature gene sets, 5219 gene sets)
    • IMMUNESIGDB (ImmuneSigDB gene sets, 4872 gene sets)
    • VAX (vaccine response gene sets, 347 gene sets)
  • C8 (cell type signature gene sets, 671 gene sets)

Gene sets starting with P

Click on a gene set name to view its gene set page.

P300_01
P53_02
P53_DECAMER_Q2
P53_DN.V1_DN
P53_DN.V1_UP
P53_DN.V2_DN
P53_DN.V2_UP
PACHER_TARGETS_OF_IGF1_AND_IGF2_UP
PAF1_TARGET_GENES
PAL_PRMT5_TARGETS_DN
PAL_PRMT5_TARGETS_UP
PALOMERO_GSI_SENSITIVITY_DN
PALOMERO_GSI_SENSITIVITY_UP
PANAPASA_BLOOD_FLUENZ_AGE_03_17YO_3
DY_4DY_DN

PANAPASA_BLOOD_FLUENZ_AGE_03_17YO_6
DY_7DY_UP

PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_A
ND_SMAD5_DN

PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_A
ND_SMAD5_UP

PAPASPYRIDONOS_UNSTABLE_ATEROSCLERO
TIC_PLAQUE_DN

PAPASPYRIDONOS_UNSTABLE_ATEROSCLERO
TIC_PLAQUE_UP

PARENT_MTOR_SIGNALING_DN
PARENT_MTOR_SIGNALING_UP
PARK_APL_PATHOGENESIS_DN
PARK_APL_PATHOGENESIS_UP
PARK_HSC_AND_MULTIPOTENT_PROGENITOR
S

PARK_HSC_MARKERS
PARK_HSC_VS_MULTIPOTENT_PROGENITORS
_DN

PARK_HSC_VS_MULTIPOTENT_PROGENITORS
_UP

PARK_OSTEOBLAST_DIFFERENTIATION_BY_
PHENYLAMIL_DN

PARK_OSTEOBLAST_DIFFERENTIATION_BY_
PHENYLAMIL_UP

PARK_TRETINOIN_RESPONSE
PARK_TRETINOIN_RESPONSE_AND_PML_RAR
A_FUSION

PARK_TRETINOIN_RESPONSE_AND_RARA_PL
ZF_FUSION

PASINI_SUZ12_TARGETS_DN
PASINI_SUZ12_TARGETS_UP
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP
PASTURAL_RIZ1_TARGETS_DN
PASTURAL_RIZ1_TARGETS_UP
PATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_
93YO_VZV_CHALLENGE_3DY_DN

PATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_
93YO_VZV_CHALLENGE_3DY_UP

PATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_
93YO_VZV_CHALLENGE_6HR_DN

PATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_
93YO_VZV_CHALLENGE_6HR_TOP_30_DEG_U
P

PATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_
93YO_VZV_CHALLENGE_6HR_UP

PATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_
93YO_VZV_CHALLENGED_POST_VACCINATIO
N_VS_UNCHALLENGED_72HR_TOP_30_DEG_U
P

PATIL_LIVER_CANCER
PATTERN_BINDING
PATTERN_RECOGNITION_RECEPTOR_ACTIVI
TY

PAX2_01
PAX2_02
PAX3_01
PAX3_B
PAX3_TARGET_GENES
PAX4_01
PAX4_02
PAX4_03
PAX4_04
PAX5_01
PAX5_02
PAX6_01
PAX6_TARGET_GENES
PAX7_TARGET_GENES
PAX8_01
PAX8_B
PAX8_TARGET_GENES
PAX_Q6
PBRM1_TARGET_GENES
PBX1_01
PBX1_02
PBXIP1_TARGET_GENES
PCGF1_TARGET_GENES
PCGF2_TARGET_GENES
PCGF6_TARGET_GENES
PDGF_ERK_DN.V1_DN
PDGF_ERK_DN.V1_UP
PDGF_UP.V1_DN
PDGF_UP.V1_UP
PEA3_Q6
PEART_HDAC_PROLIFERATION_CLUSTER_DN
PEART_HDAC_PROLIFERATION_CLUSTER_UP
PECE_MAMMARY_STEM_CELL_DN
PECE_MAMMARY_STEM_CELL_UP
PEDERSEN_METASTASIS_BY_ERBB2_ISOFOR
M_1

PEDERSEN_METASTASIS_BY_ERBB2_ISOFOR
M_3

PEDERSEN_METASTASIS_BY_ERBB2_ISOFOR
M_4

PEDERSEN_METASTASIS_BY_ERBB2_ISOFOR
M_5

PEDERSEN_METASTASIS_BY_ERBB2_ISOFOR
M_6

PEDERSEN_METASTASIS_BY_ERBB2_ISOFOR
M_7

PEDERSEN_TARGETS_OF_611CTF_ISOFORM_
OF_ERBB2

PEDRIOLI_MIR31_TARGETS_DN
PEDRIOLI_MIR31_TARGETS_UP
PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESEN
TATION_DN

PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESEN
TATION_UP

PENG_GLUCOSE_DEPRIVATION_DN
PENG_GLUTAMINE_DEPRIVATION_DN
PENG_GLUTAMINE_DEPRIVATION_UP
PENG_LEUCINE_DEPRIVATION_DN
PENG_RAPAMYCIN_RESPONSE_DN
PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA
_DN

PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA
_UP

PEPTIDYL_TYROSINE_PHOSPHORYLATION
PER1_TARGET_GENES
PEREZ_TP53_AND_TP63_TARGETS
PEREZ_TP53_TARGETS
PEREZ_TP63_TARGETS
PEROXISOMAL_MEMBRANE
PEROXISOMAL_PART
PEROXISOME
PETRETTO_BLOOD_PRESSURE_DN
PETRETTO_BLOOD_PRESSURE_UP
PETRETTO_CARDIAC_HYPERTROPHY
PETRETTO_HEART_MASS_QTL_CIS_DN
PETRETTO_HEART_MASS_QTL_CIS_UP
PETRETTO_LEFT_VENTRICLE_MASS_QTL_CI
S_DN

PETRETTO_LEFT_VENTRICLE_MASS_QTL_CI
S_UP

PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BL
OOD_DN

PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BL
OOD_UP

PETROVA_PROX1_TARGETS_DN
PETROVA_PROX1_TARGETS_UP
PGBD5_TARGET_GENES
PGF_UP.V1_DN
PGF_UP.V1_UP
PGM3_TARGET_GENES
PHB2_TARGET_GENES
PHESSE_TARGETS_OF_APC_AND_MBD2_DN
PHESSE_TARGETS_OF_APC_AND_MBD2_UP
PHF21A_TARGET_GENES
PHF2_TARGET_GENES
PHONG_TNF_RESPONSE_NOT_VIA_P38
PHONG_TNF_RESPONSE_VIA_P38_COMPLETE
PHONG_TNF_RESPONSE_VIA_P38_PARTIAL
PHONG_TNF_TARGETS_DN
PHONG_TNF_TARGETS_UP
PHOSPHOINOSITIDE_MEDIATED_SIGNALING
PIAS4_TARGET_GENES
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHO
MA_DN

PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHO
MA_UP

PID_A6B1_A6B4_INTEGRIN_PATHWAY
PID_AJDISS_2PATHWAY
PID_ALK1_PATHWAY
PID_ALK2_PATHWAY
PID_ALPHA_SYNUCLEIN_PATHWAY
PID_AMB2_NEUTROPHILS_PATHWAY
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY
PID_ANTHRAX_PATHWAY
PID_AP1_PATHWAY
PID_AR_NONGENOMIC_PATHWAY
PID_AR_PATHWAY
PID_AR_TF_PATHWAY
PID_ARF6_DOWNSTREAM_PATHWAY
PID_ARF6_PATHWAY
PID_ARF6_TRAFFICKING_PATHWAY
PID_ARF_3PATHWAY
PID_ATF2_PATHWAY
PID_ATM_PATHWAY
PID_ATR_PATHWAY
PID_AURORA_A_PATHWAY
PID_AURORA_B_PATHWAY
PID_AVB3_INTEGRIN_PATHWAY
PID_AVB3_OPN_PATHWAY
PID_BARD1_PATHWAY
PID_BCR_5PATHWAY
PID_BETA_CATENIN_DEG_PATHWAY
PID_BETA_CATENIN_NUC_PATHWAY
PID_BMP_PATHWAY
PID_CASPASE_PATHWAY
PID_CD40_PATHWAY
PID_CD8_TCR_DOWNSTREAM_PATHWAY
PID_CD8_TCR_PATHWAY
PID_CDC42_PATHWAY
PID_CDC42_REG_PATHWAY
PID_CERAMIDE_PATHWAY
PID_CIRCADIAN_PATHWAY
PID_CMYB_PATHWAY
PID_CONE_PATHWAY
PID_CXCR3_PATHWAY
PID_CXCR4_PATHWAY
PID_DELTA_NP63_PATHWAY
PID_DNA_PK_PATHWAY
PID_E2F_PATHWAY
PID_ECADHERIN_KERATINOCYTE_PATHWAY
PID_ECADHERIN_NASCENT_AJ_PATHWAY
PID_ECADHERIN_STABILIZATION_PATHWAY
PID_ENDOTHELIN_PATHWAY
PID_EPHA2_FWD_PATHWAY
PID_EPHA_FWDPATHWAY
PID_EPHB_FWD_PATHWAY
PID_EPHRINB_REV_PATHWAY
PID_EPO_PATHWAY
PID_ER_NONGENOMIC_PATHWAY
PID_ERA_GENOMIC_PATHWAY
PID_ERB_GENOMIC_PATHWAY
PID_ERBB1_DOWNSTREAM_PATHWAY
PID_ERBB1_INTERNALIZATION_PATHWAY
PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY
PID_ERBB2_ERBB3_PATHWAY
PID_ERBB4_PATHWAY
PID_ERBB_NETWORK_PATHWAY
PID_FAK_PATHWAY
PID_FANCONI_PATHWAY
PID_FAS_PATHWAY
PID_FCER1_PATHWAY
PID_FGF_PATHWAY
PID_FOXM1_PATHWAY
PID_FOXO_PATHWAY
PID_FRA_PATHWAY
PID_GLYPICAN_1PATHWAY
PID_GMCSF_PATHWAY
PID_HDAC_CLASSI_PATHWAY
PID_HDAC_CLASSII_PATHWAY
PID_HDAC_CLASSIII_PATHWAY
PID_HEDGEHOG_2PATHWAY
PID_HEDGEHOG_GLI_PATHWAY
PID_HES_HEY_PATHWAY
PID_HIF1_TFPATHWAY
PID_HIF1A_PATHWAY
PID_HIF2PATHWAY
PID_HIV_NEF_PATHWAY
PID_HNF3A_PATHWAY
PID_HNF3B_PATHWAY
PID_IFNG_PATHWAY
PID_IGF1_PATHWAY
PID_IL12_2PATHWAY
PID_IL12_STAT4_PATHWAY
PID_IL1_PATHWAY
PID_IL23_PATHWAY
PID_IL27_PATHWAY
PID_IL2_1PATHWAY
PID_IL2_PI3K_PATHWAY
PID_IL2_STAT5_PATHWAY
PID_IL3_PATHWAY
PID_IL4_2PATHWAY
PID_IL5_PATHWAY
PID_IL6_7_PATHWAY
PID_IL8_CXCR1_PATHWAY
PID_IL8_CXCR2_PATHWAY
PID_ILK_PATHWAY
PID_INSULIN_GLUCOSE_PATHWAY
PID_INSULIN_PATHWAY
PID_INTEGRIN1_PATHWAY
PID_INTEGRIN2_PATHWAY
PID_INTEGRIN3_PATHWAY
PID_INTEGRIN4_PATHWAY
PID_INTEGRIN5_PATHWAY
PID_INTEGRIN_A4B1_PATHWAY
PID_INTEGRIN_A9B1_PATHWAY
PID_INTEGRIN_CS_PATHWAY
PID_KIT_PATHWAY
PID_LIS1_PATHWAY
PID_LKB1_PATHWAY
PID_LPA4_PATHWAY
PID_LYMPH_ANGIOGENESIS_PATHWAY
PID_LYSOPHOSPHOLIPID_PATHWAY
PID_MAPK_TRK_PATHWAY
PID_MET_PATHWAY
PID_MTOR_4PATHWAY
PID_MYC_ACTIV_PATHWAY
PID_MYC_PATHWAY
PID_MYC_REPRESS_PATHWAY
PID_NCADHERIN_PATHWAY
PID_NECTIN_PATHWAY
PID_NEPHRIN_NEPH1_PATHWAY
PID_NETRIN_PATHWAY
PID_NFAT_3PATHWAY
PID_NFAT_TFPATHWAY
PID_NFKAPPAB_ATYPICAL_PATHWAY
PID_NFKAPPAB_CANONICAL_PATHWAY
PID_NOTCH_PATHWAY
PID_P38_ALPHA_BETA_DOWNSTREAM_PATHW
AY

PID_P38_ALPHA_BETA_PATHWAY
PID_P38_GAMMA_DELTA_PATHWAY
PID_P38_MK2_PATHWAY
PID_P38_MKK3_6PATHWAY
PID_P53_DOWNSTREAM_PATHWAY
PID_P53_REGULATION_PATHWAY
PID_P73PATHWAY
PID_P75_NTR_PATHWAY
PID_PDGFRA_PATHWAY
PID_PDGFRB_PATHWAY
PID_PI3K_PLC_TRK_PATHWAY
PID_PI3KCI_AKT_PATHWAY
PID_PI3KCI_PATHWAY
PID_PLK1_PATHWAY
PID_PRL_SIGNALING_EVENTS_PATHWAY
PID_PS1_PATHWAY
PID_PTP1B_PATHWAY
PID_RAC1_PATHWAY
PID_RAC1_REG_PATHWAY
PID_RANBP2_PATHWAY
PID_RAS_PATHWAY
PID_RB_1PATHWAY
PID_REELIN_PATHWAY
PID_REG_GR_PATHWAY
PID_RET_PATHWAY
PID_RETINOIC_ACID_PATHWAY
PID_RHOA_PATHWAY
PID_RHOA_REG_PATHWAY
PID_RHODOPSIN_PATHWAY
PID_RXR_VDR_PATHWAY
PID_S1P_META_PATHWAY
PID_S1P_S1P1_PATHWAY
PID_S1P_S1P2_PATHWAY
PID_S1P_S1P3_PATHWAY
PID_S1P_S1P4_PATHWAY
PID_SHP2_PATHWAY
PID_SMAD2_3NUCLEAR_PATHWAY
PID_SMAD2_3PATHWAY
PID_SYNDECAN_1_PATHWAY
PID_SYNDECAN_2_PATHWAY
PID_SYNDECAN_3_PATHWAY
PID_SYNDECAN_4_PATHWAY
PID_TAP63_PATHWAY
PID_TCPTP_PATHWAY
PID_TCR_CALCIUM_PATHWAY
PID_TCR_JNK_PATHWAY
PID_TCR_PATHWAY
PID_TCR_RAS_PATHWAY
PID_TELOMERASE_PATHWAY
PID_TGFBR_PATHWAY
PID_THROMBIN_PAR1_PATHWAY
PID_THROMBIN_PAR4_PATHWAY
PID_TNF_PATHWAY
PID_TOLL_ENDOGENOUS_PATHWAY
PID_TRAIL_PATHWAY
PID_TRKR_PATHWAY
PID_TXA2PATHWAY
PID_UPA_UPAR_PATHWAY
PID_VEGF_VEGFR_PATHWAY
PID_VEGFR1_2_PATHWAY
PID_VEGFR1_PATHWAY
PID_WNT_CANONICAL_PATHWAY
PID_WNT_NONCANONICAL_PATHWAY
PID_WNT_SIGNALING_PATHWAY
PIEPOLI_LGI1_TARGETS_DN
PIEPOLI_LGI1_TARGETS_UP
PILON_KLF1_TARGETS_DN
PILON_KLF1_TARGETS_UP
PIONTEK_PKD1_TARGETS_DN
PIONTEK_PKD1_TARGETS_UP
PIT1_Q6
PITX1_TARGET_GENES
PITX2_Q2
PKCA_DN.V1_DN
PKCA_DN.V1_UP
PLASARI_NFIC_TARGETS_BASAL_DN
PLASARI_NFIC_TARGETS_BASAL_UP
PLASARI_TGFB1_SIGNALING_VIA_NFIC_10
HR_DN

PLASARI_TGFB1_SIGNALING_VIA_NFIC_10
HR_UP

PLASARI_TGFB1_SIGNALING_VIA_NFIC_1H
R_DN

PLASARI_TGFB1_SIGNALING_VIA_NFIC_1H
R_UP

PLASARI_TGFB1_TARGETS_10HR_DN
PLASARI_TGFB1_TARGETS_10HR_UP
PLASARI_TGFB1_TARGETS_1HR_DN
PLASARI_TGFB1_TARGETS_1HR_UP
PLASMA_MEMBRANE
PLASMA_MEMBRANE_PART
PODAR_RESPONSE_TO_ADAPHOSTIN_DN
PODAR_RESPONSE_TO_ADAPHOSTIN_UP
POMEROY_MEDULLOBLASTOMA_DESMOPLASIC
_VS_CLASSIC_DN

POMEROY_MEDULLOBLASTOMA_DESMOPLASIC
_VS_CLASSIC_UP

POMEROY_MEDULLOBLASTOMA_PROGNOSIS_D
N

POMEROY_MEDULLOBLASTOMA_PROGNOSIS_U
P

POOLA_INVASIVE_BREAST_CANCER_DN
POOLA_INVASIVE_BREAST_CANCER_UP
POS_HISTAMINE_RESPONSE_NETWORK
POS_RESPONSE_TO_HISTAMINE_DN
POS_RESPONSE_TO_HISTAMINE_UP
POSITIVE_REGULATION_OF_ANGIOGENESIS
POSITIVE_REGULATION_OF_CASPASE_ACTI
VITY

POSITIVE_REGULATION_OF_CELL_MIGRATI
ON

POSITIVE_REGULATION_OF_CELLULAR_PRO
TEIN_METABOLIC_PROCESS

POSITIVE_REGULATION_OF_PHOSPHATE_ME
TABOLIC_PROCESS

POSITIVE_REGULATION_OF_PHOSPHORYLAT
ION

POSITIVE_REGULATION_OF_PROTEIN_AMIN
O_ACID_PHOSPHORYLATION

POSITIVE_REGULATION_OF_PROTEIN_SECR
ETION

POSITIVE_REGULATION_OF_RESPONSE_TO_
STIMULUS

POSITIVE_REGULATION_OF_T_CELL_ACTIV
ATION

POU1F1_Q6
POU2AF1_TARGET_GENES
POU3F2_01
POU3F2_02
POU6F1_01
PPAR_DR1_Q2
PPARA_01
PPARA_02
PPARA_TARGET_GENES
PPARG_01
PPARGC1A_TARGET_GENES
PR_01
PR_02
PR_Q2
PRAMOONJAGO_SOX4_TARGETS_DN
PRAMOONJAGO_SOX4_TARGETS_UP
PRC1_BMI_UP.V1_DN
PRC1_BMI_UP.V1_UP
PRC2_EED_UP.V1_DN
PRC2_EED_UP.V1_UP
PRC2_EZH2_UP.V1_DN
PRC2_EZH2_UP.V1_UP
PRC2_SUZ12_UP.V1_DN
PRC2_SUZ12_UP.V1_UP
PRDM12_TARGET_GENES
PRDM4_TARGET_GENES
PRDM5_TARGET_GENES
PRKDC_TARGET_GENES
PRMT5_TARGET_GENES
PROTEASOME_COMPLEX
PROTEIN_COMPLEX_BINDING
PROTEIN_KINASE_BINDING
PROTEIN_KINASE_INHIBITOR_ACTIVITY
PROTEIN_KINASE_REGULATOR_ACTIVITY
PROTEIN_RNA_COMPLEX_ASSEMBLY
PROTEIN_SECRETION
PROTEIN_UBIQUITINATION
PROTEINACEOUS_EXTRACELLULAR_MATRIX
PROVENZANI_METASTASIS_DN
PROVENZANI_METASTASIS_UP
PSIP1_TARGET_GENES
PSMB5_TARGET_GENES
PTEN_DN.V1_DN
PTEN_DN.V1_UP
PTEN_DN.V2_DN
PTEN_DN.V2_UP
PTF1BETA_Q6
PTPRA_TARGET_GENES
PTTG1_TARGET_GENES
PU1_Q6
PUIFFE_INVASION_INHIBITED_BY_ASCITE
S_DN

PUIFFE_INVASION_INHIBITED_BY_ASCITE
S_UP

PUJANA_ATM_PCC_NETWORK
PUJANA_BRCA1_PCC_NETWORK
PUJANA_BRCA2_PCC_NETWORK
PUJANA_BRCA_CENTERED_NETWORK
PUJANA_BREAST_CANCER_LIT_INT_NETWOR
K

PUJANA_BREAST_CANCER_WITH_BRCA1_MUT
ATED_DN

PUJANA_BREAST_CANCER_WITH_BRCA1_MUT
ATED_UP

PUJANA_CHEK2_PCC_NETWORK
PUJANA_XPRSS_INT_NETWORK
PURBEY_TARGETS_OF_CTBP1_AND_SATB1_D
N

PURBEY_TARGETS_OF_CTBP1_AND_SATB1_U
P

PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_D
N

PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_U
P

PXR_Q2
PYEON_CANCER_HEAD_AND_NECK_VS_CERVI
CAL_DN

PYEON_CANCER_HEAD_AND_NECK_VS_CERVI
CAL_UP

PYEON_HPV_POSITIVE_TUMORS_DN
PYEON_HPV_POSITIVE_TUMORS_UP