Table: Gene sets enriched in phenotype MUT (33 samples) [plain text format]

	GS	GS DESC	SIZE	ES	NES	NOM p-val	FDR q-val	FWER p-val
1	rasPathway	Details ...	22	-0.60	-1.89	0.002	0.284	0.176
2	ngfPathway	Details ...	19	-0.59	-1.86	0.002	0.206	0.240
3	igf1Pathway	Details ...	20	-0.56	-1.82	0.000	0.206	0.325
4	UPREG_BY_HOXA9	Details ...	29	-0.58	-1.73	0.007	0.364	0.582
5	egfPathway	Details ...	27	-0.48	-1.67	0.011	0.488	0.734
6	insulinPathway	Details ...	21	-0.49	-1.64	0.015	0.513	0.795
7	XINACT_MERGED	Details ...	16	-0.61	-1.64	0.015	0.450	0.800
8	MAPK_Cascade	Details ...	21	-0.49	-1.61	0.021	0.494	0.862
9	BRCA_UP	Details ...	39	-0.46	-1.58	0.025	0.520	0.891
10	SA_B_CELL_RECEPTOR_COMPLEXES	Details ...	23	-0.45	-1.58	0.019	0.496	0.904
11	pitx2Pathway	Details ...	16	-0.52	-1.55	0.025	0.533	0.930
12	bcrPathway	Details ...	34	-0.43	-1.55	0.013	0.492	0.931
13	NFKB_REDUCED	Details ...	21	-0.58	-1.54	0.049	0.480	0.936
14	pdgfPathway	Details ...	27	-0.45	-1.52	0.039	0.519	0.956
15	ST_ERK1_ERK2_MAPK_Pathway	Details ...	28	-0.44	-1.50	0.023	0.531	0.966
16	erkPathway	Details ...	29	-0.44	-1.50	0.033	0.523	0.970
17	gcrPathway	Details ...	18	-0.50	-1.48	0.050	0.532	0.978
18	ST_Phosphoinositide_3_Kinase_Pathway	Details ...	32	-0.40	-1.47	0.025	0.534	0.982
19	proteasomePathway	Details ...	21	-0.55	-1.42	0.125	0.677	0.994
20	pyk2Pathway	Details ...	28	-0.40	-1.42	0.057	0.649	0.994
21	at1rPathway		34	-0.38	-1.42	0.038	0.631	0.995
22	cdmacPathway		15	-0.47	-1.41	0.075	0.633	0.996
23	fmlppathway		36	-0.38	-1.39	0.064	0.657	0.996
24	hcmvPathway		16	-0.47	-1.38	0.112	0.674	0.997
25	metPathway		35	-0.37	-1.38	0.071	0.657	0.998
26	Glycogen_Metabolism		34	-0.37	-1.37	0.080	0.679	0.999
27	nkcellsPathway		18	-0.46	-1.35	0.135	0.710	1.000
28	spryPathway		16	-0.45	-1.34	0.146	0.712	1.000
29	igf1rPathway		15	-0.46	-1.34	0.123	0.705	1.000
30	aktPathway		19	-0.43	-1.33	0.114	0.689	1.000
31	fcer1Pathway		37	-0.36	-1.33	0.072	0.667	1.000
32	HTERT_UP		109	-0.37	-1.32	0.152	0.684	1.000
33	ndkDynaminPathway		17	-0.47	-1.31	0.167	0.685	1.000
34	ST_Gaq_Pathway		27	-0.38	-1.31	0.128	0.680	1.000
35	ST_Ga13_Pathway		36	-0.36	-1.29	0.126	0.727	1.000
36	ecmPathway		22	-0.40	-1.29	0.124	0.709	1.000
37	ST_B_Cell_Antigen_Receptor		38	-0.34	-1.28	0.118	0.703	1.000
38	il6Pathway		21	-0.39	-1.28	0.166	0.687	1.000
39	GLYCOGEN		20	-0.39	-1.28	0.148	0.682	1.000
40	carm-erPathway		26	-0.41	-1.26	0.202	0.716	1.000
41	cxcr4Pathway		23	-0.38	-1.24	0.168	0.747	1.000
42	tnfr2Pathway		18	-0.41	-1.23	0.199	0.769	1.000
43	ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway		31	-0.35	-1.23	0.169	0.759	1.000
44	SIG_PIP3_signaling_in_B_lymphocytes		32	-0.36	-1.23	0.193	0.752	1.000
45	eif4Pathway		24	-0.37	-1.22	0.206	0.763	1.000
46	relaPathway		16	-0.43	-1.22	0.241	0.748	1.000
47	SIG_Regulation_of_the_actin_cytoskeleton_by_Rho_GTPases		31	-0.38	-1.21	0.216	0.747	1.000
48	mapkPathway		82	-0.28	-1.20	0.164	0.752	1.000
49	gsk3Pathway		24	-0.37	-1.20	0.212	0.749	1.000
50	ANDROGEN_UP_GENES		57	-0.30	-1.20	0.181	0.746	1.000
51	P53_DOWN		17	-0.40	-1.19	0.242	0.746	1.000
52	SIG_PIP3SIGINCARDIACMYOCTES		61	-0.28	-1.19	0.188	0.744	1.000
53	CR_PROTEIN_MOD		146	-0.25	-1.18	0.142	0.734	1.000
54	SIG_CHEMOTAXIS		40	-0.32	-1.18	0.234	0.735	1.000
55	GLUT_UP		269	-0.27	-1.18	0.235	0.723	1.000
56	tollPathway		29	-0.34	-1.16	0.255	0.763	1.000
57	integrinPathway		33	-0.34	-1.16	0.253	0.752	1.000
58	ccr3Pathway		22	-0.35	-1.15	0.277	0.758	1.000
59	G13_Signaling_Pathway		28	-0.37	-1.15	0.291	0.745	1.000
60	gleevecPathway		22	-0.34	-1.15	0.263	0.735	1.000
61	rac1Pathway		22	-0.36	-1.15	0.268	0.727	1.000
62	vegfPathway		24	-0.34	-1.15	0.276	0.718	1.000
63	EMT_DOWN		39	-0.33	-1.15	0.254	0.708	1.000
64	deathPathway		31	-0.34	-1.15	0.273	0.705	1.000
65	MAP00510_N_Glycans_biosynthesis		15	-0.40	-1.15	0.272	0.694	1.000
66	SA_TRKA_RECEPTOR		16	-0.39	-1.14	0.282	0.684	1.000
67	epoPathway		19	-0.34	-1.13	0.282	0.701	1.000
68	ptenPathway		17	-0.37	-1.13	0.291	0.696	1.000
69	gpcrPathway		33	-0.30	-1.11	0.308	0.747	1.000
70	RAR_UP		31	-0.34	-1.10	0.326	0.745	1.000
71	HUMAN_CD34_ENRICHED_TF_JP		175	-0.26	-1.10	0.307	0.749	1.000
72	nfatPathway		47	-0.30	-1.10	0.311	0.748	1.000
73	cell_cycle_checkpoint		25	-0.40	-1.09	0.379	0.756	1.000
74	HOXA9_DOWN		31	-0.30	-1.06	0.369	0.833	1.000
75	tumor_supressor		22	-0.34	-1.05	0.383	0.829	1.000
76	sppaPathway		22	-0.33	-1.05	0.376	0.824	1.000
77	mef2dPathway		19	-0.36	-1.04	0.405	0.835	1.000
78	arapPathway		17	-0.32	-1.04	0.401	0.834	1.000
79	tnfr1Pathway		27	-0.31	-1.04	0.411	0.825	1.000
80	tpoPathway		23	-0.31	-1.03	0.410	0.828	1.000
81	RAP_UP		170	-0.23	-1.02	0.394	0.848	1.000
82	keratinocytePathway		45	-0.26	-1.02	0.422	0.850	1.000
83	il2Pathway		22	-0.32	-1.02	0.427	0.843	1.000
84	hivnefPathway		54	-0.27	-1.00	0.445	0.872	1.000
85	Proteasome_Degradation		31	-0.33	-1.00	0.461	0.866	1.000
86	cell_motility		99	-0.23	-1.00	0.455	0.861	1.000
87	FETAL_LIVER_HS_ENRICHED_TF_JP		68	-0.26	-1.00	0.455	0.855	1.000
88	cell_cycle_arrest		30	-0.30	-0.98	0.509	0.887	1.000
89	CR_SIGNALLING		182	-0.21	-0.97	0.497	0.910	1.000
90	ST_ADRENERGIC		35	-0.26	-0.97	0.538	0.901	1.000
91	tnf_and_fas_network		20	-0.33	-0.96	0.483	0.913	1.000
92	SIG_InsulinReceptorPathwayInCardiacMyocytes		48	-0.23	-0.96	0.544	0.904	1.000
93	ST_Integrin_Signaling_Pathway		74	-0.23	-0.94	0.548	0.933	1.000
94	CR_CELL_CYCLE		78	-0.30	-0.94	0.500	0.925	1.000
95	MAP03020_RNA_polymerase		15	-0.33	-0.94	0.533	0.921	1.000
96	insulin_signalling		97	-0.21	-0.93	0.592	0.925	1.000
97	Cell_Cycle		72	-0.32	-0.93	0.531	0.931	1.000
98	tcrPathway		45	-0.31	-0.93	0.557	0.922	1.000
99	nfkbPathway		22	-0.29	-0.93	0.548	0.915	1.000
100	ST_p38_MAPK_Pathway		34	-0.27	-0.92	0.566	0.912	1.000
101	INSULIN_2F_UP		169	-0.23	-0.91	0.567	0.928	1.000
102	alkPathway		31	-0.26	-0.91	0.615	0.923	1.000
103	GLUCOSE_DOWN		145	-0.22	-0.91	0.607	0.916	1.000
104	ST_JNK_MAPK_Pathway		37	-0.24	-0.90	0.636	0.946	1.000
105	SA_PTEN_PATHWAY		16	-0.31	-0.89	0.624	0.946	1.000
106	MAP00260_Glycine_serine_and_threonine_metabolism		22	-0.27	-0.88	0.621	0.958	1.000
107	mtorPathway		23	-0.29	-0.88	0.633	0.969	1.000
108	ccr5Pathway		17	-0.29	-0.87	0.629	0.968	1.000
109	DOWNREG_BY_HOXA9		28	-0.26	-0.87	0.661	0.965	1.000
110	il7Pathway		16	-0.33	-0.87	0.617	0.957	1.000
111	SIG_CD40PATHWAYMAP		34	-0.24	-0.86	0.676	0.965	1.000
112	LEU_DOWN		165	-0.25	-0.86	0.616	0.957	1.000
113	41bbPathway		18	-0.27	-0.86	0.643	0.952	1.000
114	fasPathway		28	-0.28	-0.86	0.634	0.944	1.000
115	pgc1aPathway		22	-0.25	-0.86	0.682	0.937	1.000
116	il3Pathway		15	-0.29	-0.86	0.669	0.929	1.000
117	mRNA_processing		40	-0.35	-0.86	0.605	0.923	1.000
118	hdacPathway		29	-0.24	-0.85	0.716	0.927	1.000
119	TESTIS_GENES_FROM_XHX_AND_NETAFFX		46	-0.23	-0.85	0.723	0.928	1.000
120	GLUCOSE_UP		38	-0.24	-0.85	0.669	0.920	1.000
121	biopeptidesPathway		37	-0.23	-0.85	0.724	0.914	1.000
122	MAP00480_Glutathione_metabolism		16	-0.28	-0.84	0.653	0.926	1.000
123	MAP00970_Aminoacyl_tRNA_biosynthesis		16	-0.37	-0.83	0.637	0.926	1.000
124	FRASOR_ER_DOWN		68	-0.23	-0.83	0.694	0.926	1.000
125	breast_cancer_estrogen_signalling		97	-0.20	-0.82	0.751	0.938	1.000
126	cd40Pathway		15	-0.28	-0.81	0.669	0.945	1.000
127	HEMO_TF_LIST_JP		77	-0.20	-0.81	0.794	0.945	1.000
128	ST_MONOCYTE_AD_PATHWAY		25	-0.23	-0.81	0.806	0.939	1.000
129	MAP00280_Valine_leucine_and_isoleucine_degradation		23	-0.29	-0.79	0.706	0.958	1.000
130	Wnt_Signaling		43	-0.20	-0.79	0.827	0.960	1.000
131	MAP00051_Fructose_and_mannose_metabolism		20	-0.26	-0.78	0.752	0.965	1.000
132	edg1Pathway		24	-0.24	-0.78	0.791	0.958	1.000
133	ST_Differentiation_Pathway_in_PC12_Cells		43	-0.20	-0.77	0.850	0.968	1.000
134	par1Pathway		20	-0.25	-0.77	0.787	0.968	1.000
135	MAP00252_Alanine_and_aspartate_metabolism		21	-0.23	-0.77	0.764	0.964	1.000
136	CR_CYTOSKELETON		23	-0.26	-0.76	0.782	0.961	1.000
137	caspasePathway		21	-0.29	-0.76	0.756	0.956	1.000
138	ghPathway		27	-0.22	-0.76	0.827	0.956	1.000
139	wntPathway		23	-0.23	-0.76	0.812	0.951	1.000
140	MAP00150_Androgen_and_estrogen_metabolism		17	-0.25	-0.73	0.841	0.983	1.000
141	erk5Pathway		17	-0.23	-0.73	0.854	0.978	1.000
142	MAP00361_gamma_Hexachlorocyclohexane_degradation		26	-0.22	-0.72	0.855	0.980	1.000
143	Fatty_Acid_Degradation		18	-0.26	-0.72	0.767	0.978	1.000
144	GLUT_DOWN		285	-0.19	-0.71	0.775	0.985	1.000
145	mRNA_splicing		47	-0.26	-0.69	0.782	0.997	1.000
146	atrbrcaPathway		19	-0.27	-0.68	0.802	1.000	1.000
147	PGC		315	-0.15	-0.68	0.965	0.998	1.000
148	MAP00310_Lysine_degradation		16	-0.24	-0.67	0.872	0.998	1.000
149	CR_TRANSPORT_OF_VESICLES		21	-0.22	-0.67	0.865	0.996	1.000
150	tRNA_Synthetases		17	-0.29	-0.66	0.787	0.994	1.000
151	MAP00410_beta_Alanine_metabolism		17	-0.21	-0.66	0.917	0.991	1.000
152	MAP00220_Urea_cycle_and_metabolism_of_amino_groups		18	-0.22	-0.65	0.919	0.992	1.000
153	p38mapkPathway		39	-0.16	-0.64	0.968	0.993	1.000
154	ST_Tumor_Necrosis_Factor_Pathway		28	-0.20	-0.63	0.910	0.994	1.000
155	NFKB_INDUCED		106	-0.18	-0.62	0.946	0.996	1.000
156	stressPathway		25	-0.18	-0.61	0.955	0.998	1.000
157	MAP00340_Histidine_metabolism		20	-0.21	-0.60	0.950	0.998	1.000
158	ST_Wnt_beta_catenin_Pathway		22	-0.20	-0.59	0.956	0.994	1.000
159	RAP_DOWN		211	-0.17	-0.59	0.921	0.988	1.000
160	GATA1_WEISS		20	-0.26	-0.59	0.951	0.983	1.000
161	MAP00240_Pyrimidine_metabolism		41	-0.18	-0.58	0.943	0.981	1.000
162	fatty_acid_metabolism		20	-0.17	-0.51	0.983	1.000	1.000
163	MAP00251_Glutamate_metabolism		19	-0.17	-0.48	0.984	1.000	1.000
164	CR_DNA_MET_AND_MOD		24	-0.16	-0.46	0.986	0.999	1.000
165	Electron_Transport_Chain		67	-0.17	-0.46	0.948	0.994	1.000